Matthew G. Nayor, MD, MPH

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women's Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.

Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.

Publications

  • Published 5/15/2025

    El-Sabawi B, Tanriverdi K, Gajjar P, Nayor M, Landman JM, Below JE, Haff M, Long M, Ezpeleta M, Freedman JE, Varady K, Shah R, Perry AS. Circulating Proteomics Identifies a Dynamic Profile of Hepatic Steatosis During Metabolic Intervention. J Am Heart Assoc. 2025 May 15; e037100. PMID: 40371575.

    Read at: PubMed

  • Published 3/7/2025

    El-Sabawi B, Betti M, Lin P, Huang X, Kim N, Yaser Anwar M, Perry AS, Perera BLA, Gajjar P, Colangelo LA, Amancherla K, Sheng Q, Zhao S, Stolze L, Farber-Eger E, Landman JM, Miller PE, Liu GY, Das S, Wells QS, Terry JG, Lloyd-Jones D, Das S, Khan SS, North KE, Below J, Nayor M, Kalhan R, Carr JJ, Gamazon ER, Shah RV. Molecular architecture of human atherosclerosis revealed through integrative human genetics. medRxiv. 2025 Mar 07. PMID: 40093223.

    Read at: PubMed

  • Published 2/14/2025

    Iyer KR, Clarke SL, Guarischi-Sousa R, Gjoni K, Heath AS, Young EP, Stitziel NO, Laurie C, Broome JG, Khan AT, Lewis JP, Xu H, Montasser ME, Ashley KE, Hasbani NR, Boerwinkle E, Morrison AC, Chami N, Do R, Rocheleau G, Lloyd-Jones DM, Lemaitre RN, Bis JC, Floyd JS, Kinney GL, Bowden DW, Palmer ND, Benjamin EJ, Nayor M, Yanek LR, Kral BG, Becker LC, Kardia SLR, Smith JA, Bielak LF, Norwood AF, Min YI, Carson AP, Post WS, Rich SS, Herrington D, Guo X, Taylor KD, Manson JE, Franceschini N, Pollard KS, Mitchell BD, Loos RJF, Fornage M, Hou L, Psaty BM, Young KA, Regan EA, Freedman BI, Vasan RS, Levy D, Mathias RA, Peyser PA, Raffield LM, Kooperberg C, Reiner AP, Rotter JI, Jun G, de Vries PS, Assimes TL. Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants. J Am Heart Assoc. 2025 Feb 18; 14(4):e036499. PMID: 39950338.

    Read at: PubMed

  • Published 1/7/2025

    Rade JJ, Kronsberg SS, Kickler TS, Vasan RS, Xanthakis V, Nayor MG, Barton BA. Association of Systemic Thromboxane Generation With Risk of Developing Heart Failure. J Am Coll Cardiol. 2025 Jan 07; 85(1):58-70. PMID: 39779056.

    Read at: PubMed

  • Published 1/1/2025

    Florea VV, Gajjar P, Huang S, Tang J, Zhao S, Davenport M, Mi MY, Haff M, Zhang X, Miller PE, Vasan RS, Liu CT, Lewis GD, Shah RV, Long MT, Nayor M. Hepatic Steatosis and Fibrosis, Cardiorespiratory Fitness, and Metabolic Mediators in the Community. Liver Int. 2025 Jan; 45(1):e16147. PMID: 39673712.

    Read at: PubMed

Other Positions

  • Assistant Professor, Medicine
    Boston University Chobanian & Avedisian School of Medicine

Education

  • New York University School of Medicine, MD
  • Harvard School of Public Health, MPH
  • University of Michigan at Ann Arbor, BA