Matthew G. Nayor, MD, MPH

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women's Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.

Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.

Publications

  • Published 8/23/2025

    Jha M, Dong Z, Ruda MM, Prescott B, Xanthakis V, Nayor M, Gajjar P, Larson MG, Benjamin EJ, Vasan RS, Mitchell GF, Tsao CW. Associations of cardiovascular health with arterial health in adults free of cardiovascular disease. Am J Prev Cardiol. 2025 Sep; 23:101083. PMID: 40918934.

    Read at: PubMed

  • Published 7/26/2025

    Lindman BR, Perry AS, Lance ML, Amancherla K, Kim N, Sheng Q, Lin P, Pfeiffer RD, Farber-Eger E, Fearon WF, Kapadia S, Kumbhani DJ, Gillam L, Mallugari RR, Gupta DK, Miller FJ, Vatterott A, Jackson N, Su YR, Tomasek K, Absi T, Freedman JE, Nayor M, Das S, Wells QS, Dweck MR, Gerszten RE, Gamazon ER, Tucker NR, Shah R, Elmariah S. Integrated multiomics of pressure overload in the human heart prioritizes targets relevant to heart failure. Nat Commun. 2025 Jul 26; 16(1):6889. PMID: 40715126.

    Read at: PubMed

  • Published 7/3/2025

    Mi MY, Perry AS, Krishnan V, Nayor M. Epidemiology and Cardiovascular Benefits of Physical Activity and Exercise. Circ Res. 2025 Jul 07; 137(2):120-138. PMID: 40608856.

    Read at: PubMed

  • Published 6/3/2025

    Wang X, Zhang Y, Pathiravasan CH, Spartano NL, Benjamin EJ, McManus DD, Lewis GD, Larson MG, Vasan RS, Murabito JM, Liu C, Nayor M. Blood Pressure Responses During Exercise Were Associated With Average Home Blood Pressure and Home Blood Pressure Variability: The Electronic Framingham Heart Study. J Am Heart Assoc. 2025 Jun 03; 14(11):e039457. PMID: 40459124.

    Read at: PubMed

  • Published 5/31/2025

    Toro C, Daniels AS, Prescott B, Xanthakis V, Nayor M, Gajjar P, Benjamin EJ, Preis SR. Association of life's essential 8 score with incidence of atrial fibrillation: The Framingham heart study. Am J Prev Cardiol. 2025 Sep; 23:101018. PMID: 40585337.

    Read at: PubMed

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Other Positions

  • Assistant Professor, Medicine
    Boston University Chobanian & Avedisian School of Medicine

Websites

Education

  • New York University School of Medicine, MD
  • Harvard School of Public Health, MPH
  • University of Michigan at Ann Arbor, BA

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