Kostas Alysandratos, MD, PHD

Assistant Professor, Medicine

Kostas Alysandratos
670 Albany Street

Biography

Dr. Konstantinos D. Alysandratos, MD, PhD is an Assistant Professor in the Department of Medicine at Boston University School of Medicine and is part of the team at the Center for Regenerative Medicine at Boston University as part of Dr. Darrell N. Kotton’s lab. He received his Doctorate of Medicine from the University of Athens and embarked on his research journey after winning a competitive 3-year scholarship from the Hellenic State Scholarships Foundation. As part of his doctoral work under the mentorship of Dr. Theoharides at Tufts University, he studied the interplay between neuropeptides and cytokines in the pathogenesis of atopic dermatitis and their role on mast cell activation. He has also contributed to translational discoveries relating to mast cell activation in neurodevelopmental disorders such as autism spectrum disorders that may inform novel therapeutic approaches. Dr. Alysandratos completed his internal medicine training at UT Southwestern Medical Center, during which time he developed his passion for intensive and pulmonary care.

Education

  • , MD/PhD

Publications

  • Published on 4/12/2018

    McCauley KB, Alysandratos KD, Jacob A, Hawkins F, Caballero IS, Vedaie M, Yang W, Slovik KJ, Morley M, Carraro G, Kook S, Guttentag SH, Stripp BR, Morrisey EE, Kotton DN. Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium. Stem Cell Reports. 2018 05 08; 10(5):1579-1595. PMID: 29657097.

    Read at: PubMed
  • Published on 9/25/2017

    Serra M, Alysandratos KD, Hawkins F, McCauley KB, Jacob A, Choi J, Caballero IS, Vedaie M, Kurmann AA, Ikonomou L, Hollenberg AN, Shannon JM, Kotton DN. Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification. Development. 2017 11 01; 144(21):3879-3893. PMID: 28947536.

    Read at: PubMed
  • Published on 1/1/2017

    Alysandratos KD, Serra M, Mulugeta S, Beers MF, Kotton DN. Am J Respi Crit Care Med. Deriving alveolar type 2 cells from pluripotent stem cells to model surfactant protein C (SP-C) mutations in vitro. 2017; 195:A4317.

  • Published on 11/2/2015

    Ceglia L, Nelson J, Ware J, Alysandratos KD, Bray GA, Garganta C, Nathan DM, Hu FB, Dawson-Hughes B, Pittas AG. Association between body weight and composition and plasma 25-hydroxyvitamin D level in the Diabetes Prevention Program. Eur J Nutr. 2017 Feb; 56(1):161-170. PMID: 26525562.

    Read at: PubMed
  • Published on 9/1/2013

    Vasiadi M, Mondolfi AP, Alysandratos KD, Therianou A, Katsarou-Katsari A, Petrakopoulou T, Theoharidis A, Miniati A, Theoharides TC. Neurotensin serum levels and skin gene expression are increased in atopic dermatitis. Br J Dermatol. 2013 Sep; 169(3):695-9. PMID: 24033157.

    Read at: PubMed
  • Published on 11/14/2012

    Alysandratos KD, Asadi S, Angelidou A, Zhang B, Sismanopoulos N, Yang H, Critchfield A, Theoharides TC. Neurotensin and CRH interactions augment human mast cell activation. PLoS One. 2012; 7(11):e48934. PMID: 23155429.

    Read at: PubMed
  • Published on 7/2/2012

    Angelidou A, Asadi S, Alysandratos KD, Karagkouni A, Kourembanas S, Theoharides TC. Perinatal stress, brain inflammation and risk of autism-review and proposal. BMC Pediatr. 2012 Jul 02; 12:89. PMID: 22747567.

    Read at: PubMed
  • Published on 5/14/2012

    Vasiadi M, Therianou A, Alysandratos KD, Katsarou-Katsari A, Petrakopoulou T, Theoharides A, Papadavid E, Stavrianeas N, Antoniou C, Kalogeromitros D, Theoharides TC. Serum neurotensin (NT) is increased in psoriasis and NT induces vascular endothelial growth factor release from human mast cells. Br J Dermatol. 2012 Jun; 166(6):1349-52. PMID: 22283733.

    Read at: PubMed
  • Published on 4/27/2012

    Zhang B, Weng Z, Sismanopoulos N, Asadi S, Therianou A, Alysandratos KD, Angelidou A, Shirihai O, Theoharides TC. Mitochondria distinguish granule-stored from de novo synthesized tumor necrosis factor secretion in human mast cells. Int Arch Allergy Immunol. 2012; 159(1):23-32. PMID: 22555146.

    Read at: PubMed
  • Published on 3/22/2012

    Theoharides TC, Enakuaa S, Sismanopoulos N, Asadi S, Papadimas EC, Angelidou A, Alysandratos KD. Contribution of stress to asthma worsening through mast cell activation. Ann Allergy Asthma Immunol. 2012 Jul; 109(1):14-9. PMID: 22727152.

    Read at: PubMed

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