Dr. Steiling is an Assistant Professor of Medicine. She sees patients in the multidisciplinary Thoracic Oncology Clinic and attends in the Medical Intensive Care Unit at Boston Medical Center.
Dr. Steiling’s research focuses on applying high-throughput genomic tools and emerging computational methods to develop improved diagnostics, prognostics, and risk stratification tools for phenotypically complex lung diseases such as chronic obstructive pulmonary disease (COPD) and lung cancer. Dr. Steiling’s primary research involves gene expression profiling of the airway epithelium from individuals with COPD in order to understand the molecular mechanisms of this disease and its relationship to lung cancer. She has also worked to apply airway gene expression profiling to the diagnosis of lung cancer, to understand the relationship between smoking-induced changes in gene expression in the bronchial airway and the upper airway, and to elucidate the relationship between smoking-induced changes in airway gene and protein expression.
Research interests include:
-Airway gene expression
-Chronic Obstructive Pulmonary Disease (COPD)
Clinical interests include:
-Critical Care Medicine
- Member, Bioinformatics Graduate Program, Boston University
- Boston University School of Medicine, MD
- Boston University, MSc
- Boston College, BS
- Published on 12/21/2017
Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Spira A, Lenburg ME, Guryev V, Postma DS, van den Berge M. Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression. Respir Res. 2017 Dec 21; 18(1):213. PMID: 29268739.
- Published on 1/1/2017
Christenson SA, Steiling K. Shifting from Correlation to Causation: Challenges for the Future of Unbiased Molecular Studies in Inflammatory Lung Disease. Am J Respir Crit Care Med. 2017 01 01; 195(1):5-7. PMID: 28035851.
- Published on 11/1/2016
Bhatt N, Sloan JM, O'Hara CJ, Oommen R, Steiling K, Litle VR. Extranodal Marginal Zone Endobronchial Lymphoma Associated With Hepatitis C. Ann Thorac Surg. 2016 Nov; 102(5):e407-e408. PMID: 27772593.
- Published on 10/14/2015
Wang TW, Vermeulen RC, Hu W, Liu G, Xiao X, Alekseyev Y, Xu J, Reiss B, Steiling K, Downward GS, Silverman DT, Wei F, Wu G, Li J, Lenburg ME, Rothman N, Spira A, Lan Q. Gene-expression profiling of buccal epithelium among non-smoking women exposed to household air pollution from smoky coal. Carcinogenesis. 2015 Dec; 36(12):1494-501. PMID: 26468118.
- Published on 5/15/2015
Steiling K, Christenson SA. Targeting 'types: Precision Medicine in Pulmonary Disease. Am J Respir Crit Care Med. 2015 May 15; 191(10):1093-4. PMID: 25978565.
- Published on 5/1/2015
Grayson PC, Steiling K, Platt M, Berman JS, Zhang X, Xiao J, Alekseyev YO, Liu G, Monach PA, Kaplan MJ, Spira A, Merkel PA. Defining the nasal transcriptome in granulomatosis with polyangiitis (Wegener's). Arthritis Rheumatol. 2015 May; 67(8):2233-9. PMID: 25939343.
- Published on 4/1/2015
Christenson SA, Steiling K, van den Berge M, Hijazi K, Hiemstra PS, Postma DS, Lenburg ME, Spira A, Woodruff PG. Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2015 Apr 1; 191(7):758-66. PMID: 25611785.
- Published on 1/27/2015
Gesthalter YB, Vick J, Steiling K, Spira A. Translating the transcriptome into tools for the early detection and prevention of lung cancer. Thorax. 2015 May; 70(5):476-81. PMID: 25628310.
- Published on 12/15/2014
Stevenson EK, Sloan KA, Narsule CK, Kretschman DM, Sarita-Reyes CD, Steiling K, Ebright MI. Catamenial hemothorax in a patient with multiple sclerosis. Am J Respir Crit Care Med. 2014 Dec 15; 190(12):e69-70. PMID: 25496111.
- Published on 9/2/2014
Lamontagne M, Timens W, Hao K, Bossé Y, Laviolette M, Steiling K, Campbell JD, Couture C, Conti M, Sherwood K, Hogg JC, Brandsma CA, van den Berge M, Sandford A, Lam S, Lenburg ME, Spira A, Paré PD, Nickle D, Sin DD, Postma DS. Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction. Thorax. 2014 Nov; 69(11):997-1004. PMID: 25182044.
View 13 more publications: View full profile at BUMC