Dr. Steiling is a Pulmonary/Critical Care Physician-Scientist with a longstanding interest in improving the ability to effectively detect, treat, and cure smoking-induced lung diseases such as lung cancer and chronic obstructive pulmonary disease (COPD). She completed her fellowship training in Pulmonary and Critical Care Medicine at Boston University Medical Center, and concurrently completed a Master of Science in Bioinformatics through the Boston University College of Engineering.
Dr. Steiling’s research centers on improving the diagnosis, treatment and prevention of lung cancer and COPD. Using the airway field of injury hypothesis, which posits that cigarette smoking induces molecular changes throughout the respiratory tract, she has studied alterations in the airway transcriptome that reflect the presence, susceptibility, and progression of smoking-induced lung diseases. She has used whole-genome expression profiling of the bronchial airway epithelium to describe the relationship between upper and lower airway gene expression, and leveraged this information to develop clinically-relevant biomarkers of lung cancer, COPD, and other diseases that affect the lung.
In addition to her translational research, Dr. Steiling has led the implementation of two important clinical programs focused on improving the early detection of lung cancer in at-risk individuals. She founded the Boston Medical Center Lung Nodule Clinic, a sub-specialty referral resource that supports the evidence-based evaluation of incidental pulmonary nodules detected by diagnostic and screening CT scans. She also led the implementation of a multi-disciplinary Lung Cancer Screening Program at Boston Medical Center. Her team was recognized with a 2016 Clinical Quality Improvement Award from the Boston University Medical Center Evans Foundation. She currently co-chairs the Boston Medical Center Lung Cancer Screening Steering Committee.
Dr. Steiling sees patients in the Lung Nodule Clinic, multi-disciplinary Thoracic Oncology Clinic and attends in the Medical Intensive Care Unit at Boston Medical Center.
- Member, BU-BMC Cancer Center, Boston University
- Member, Pulmonary Center, Boston University
- Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
- Member, Bioinformatics Graduate Program, Boston University
- Member, Genome Science Institute, Boston University
- Boston University School of Medicine, MD
- Boston University, MSc
- Boston College, BS
- Published on 12/2/2020
Crable EL, Feeney T, Harvey J, Grim V, Drainoni ML, Walkey AJ, Steiling K, Drake FT. Management Strategies to Promote Follow-Up Care for Incidental Findings: A Scoping Review. J Am Coll Radiol. 2021 Apr; 18(4):566-579. PMID: 33278340.
- Published on 10/15/2020
Faiz A, Imkamp K, van der Wiel E, Boudewijn IM, Koppelman GH, Brandsma CA, Kerstjens HAM, Timens W, Vroegop S, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Steiling K, Spira A, Lenburg ME, Heijink IH, Postma DS, van den Berge M. Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD. Sci Rep. 2020 10 15; 10(1):17415. PMID: 33060632.
- Published on 6/30/2020
Iaccarino JM, Steiling K, Slatore CG, Drainoni ML, Wiener RS. Patient characteristics associated with adherence to pulmonary nodule guidelines. Respir Med. 2020 09; 171:106075. PMID: 32658836.
- Published on 1/22/2020
Steiling K, Loui T, Asokan S, Nims S, Moreira P, Rebello A, Litle VR, Suzuki K. Age, Race, and Income Are Associated With Lower Screening Rates at a Safety Net Hospital. Ann Thorac Surg. 2020 05; 109(5):1544-1550. PMID: 31981498.
- Published on 5/6/2019
Hijazi K, Malyszko B, Steiling K, Xiao X, Liu G, Alekseyev YO, Dumas YM, Hertsgaard L, Jensen J, Hatsukami D, Brooks DR, O'Connor G, Beane J, Lenburg ME, Spira A. Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation. Sci Rep. 2019 05 06; 9(1):6978. PMID: 31061400.
- Published on 4/25/2019
Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, Borggrewe M, Eijgenraam TR, Jonker MR, Koppelman GH, Pouwels SD, Liu G, Alekseyev YO, Lam S, Hiemstra PS, Sterk PJ, Timens W, Brandsma CA, Heijink IH, van den Berge M. Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD. Eur Respir J. 2019 04; 53(4). PMID: 30846474.
- Published on 1/1/2019
Hersh CP, Adcock IM, Celedón JC, Cho MH, Christiani DC, Himes BE, Kaminski N, Mathias RA, Meyers DA, Quackenbush J, Redline S, Steiling KA, Tabor HK, Tobin MD, Wurfel MM, Yang IV, Koppelman GH. High-Throughput Sequencing in Respiratory, Critical Care, and Sleep Medicine Research. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2019 01; 16(1):1-16. PMID: 30592451.
- Published on 12/1/2018
Iaccarino JM, Steiling KA, Wiener RS. Lung Cancer Screening in a Safety-Net Hospital: Implications of Screening a Real-World Population versus the National Lung Screening Trial. Ann Am Thorac Soc. 2018 12; 15(12):1493-1495. PMID: 30199643.
- Published on 4/6/2018
Abston E, Novaco R, Hon S, Scalera J, Steiling K. Breath of relief: apparent pulmonary nodule due to heterotopic ossification. Clin Case Rep. 2018 Jun; 6(6):1174-1175. PMID: 29881589.
- Published on 2/9/2018
Muñoz-Largacha JA, Steiling KA, Kathuria H, Charlot M, Fitzgerald C, Suzuki K, Litle VR. Initial surgical experience following implementation of lung cancer screening at an urban safety net hospital. J Thorac Cardiovasc Surg. 2018 06; 155(6):2674-2681. PMID: 29534906.
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