Jonathan D Cherry, PhD
Assistant Professor, Pathology & Laboratory Medicine
Biography
Background
Dr. Cherry is an Assistant Professor of Pathology and Laboratory Medicine. He completed his undergraduate studies with a BS in biology at Ursinus College in 2008. He earned his doctoral degree in Pathology from the University of Rochester in 2015. Dr. Cherry joined the McKee laboratory as a postdoctoral researcher the same year. He was appointed as an assistant professor at Chobanian and Avedisian School of Medicine in 2019. Dr. Cherry also holds a research health scientist position within the VA Boston Healthcare System. His laboratory space is located at the Jamaica Plain VA hospital where he performs his research and helps support the VA-BU-CLF brain bank.
Research Interests
Dr. Cherry’s research interests focus on understanding how neuroinflammation after repetitive traumatic brain injury contributes to CTE pathogenesis. Specifically, Dr. Cherry seeks to identify what role microglia and inflammatory cytokines play in the early onset of hyperphosphorylated tau accumulation and spread.
Dr. Cherry’s research also extend to histology analysis. He is the director of the digital pathology hub present within the BU CTE center. This research entails exploring novel ways to analyze human postmortem tissue for neuropathologic targets and better characterize pathology across a spectrum of neurodegenerative disease including Alzheimer’s disease, chronic traumatic encephalopathy, frontotemporal lobar degeneration, motor neuron diseases, and others.
Other Positions
- Assistant Professor, Neurology, Boston University Chobanian & Avedisian School of Medicine
Education
- University of Rochester, PhD
- Ursinus College, BS
Publications
- Published on 2/9/2024
van Amerongen S, Pulukuri SV, Tuz-Zahra F, Tripodis Y, Cherry JD, Bernick C, Geda YE, Wethe JV, Katz DI, Alosco ML, Adler CH, Balcer LJ, Ashton NJ, Blennow K, Zetterberg H, Daneshvar DH, Colasurdo EA, Iliff JJ, Li G, Peskind ER, Shenton ME, Reiman EM, Cummings JL, Stern RA. Inflammatory biomarkers for neurobehavioral dysregulation in former American football players: findings from the DIAGNOSE CTE Research Project. J Neuroinflammation. 2024 Feb 09; 21(1):46. PMID: 38336728.
Read at: PubMed - Published on 10/1/2023
McKee AC, Mez J, Abdolmohammadi B, Butler M, Huber BR, Uretsky M, Babcock K, Cherry JD, Alvarez VE, Martin B, Tripodis Y, Palmisano JN, Cormier KA, Kubilus CA, Nicks R, Kirsch D, Mahar I, McHale L, Nowinski C, Cantu RC, Stern RA, Daneshvar D, Goldstein LE, Katz DI, Kowall NW, Dwyer B, Stein TD, Alosco ML. Neuropathologic and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts. JAMA Neurol. 2023 Oct 01; 80(10):1037-1050. PMID: 37639244.
Read at: PubMed - Published on 7/25/2023
Rosen G, Kirsch D, Horowitz S, Cherry JD, Nicks R, Kelley H, Uretsky M, Dell'Aquila K, Mathias R, Cormier KA, Kubilus CA, Mez J, Tripodis Y, Stein TD, Alvarez VE, Alosco ML, McKee AC, Huber BR. Three dimensional evaluation of cerebrovascular density and branching in chronic traumatic encephalopathy. Acta Neuropathol Commun. 2023 Jul 25; 11(1):123. PMID: 37491342.
Read at: PubMed - Published on 6/20/2023
Daneshvar DH, Nair ES, Baucom ZH, Rasch A, Abdolmohammadi B, Uretsky M, Saltiel N, Shah A, Jarnagin J, Baugh CM, Martin BM, Palmisano JN, Cherry JD, Alvarez VE, Huber BR, Weuve J, Nowinski CJ, Cantu RC, Zafonte RD, Dwyer B, Crary JF, Goldstein LE, Kowall NW, Katz DI, Stern RA, Tripodis Y, Stein TD, McClean MD, Alosco ML, McKee AC, Mez J. Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males. Nat Commun. 2023 Jun 20; 14(1):3470. PMID: 37340004.
Read at: PubMed - Published on 3/9/2023
Labadorf A, Agus F, Aytan N, Cherry J, Mez J, McKee A, Stein TD. Inflammation and neuronal gene expression changes differ in early versus late chronic traumatic encephalopathy brain. BMC Med Genomics. 2023 Mar 09; 16(1):49. PMID: 36895005.
Read at: PubMed - Published on 2/10/2023
McKee AC, Stein TD, Huber BR, Crary JF, Bieniek K, Dickson D, Alvarez VE, Cherry JD, Farrell K, Butler M, Uretsky M, Abdolmohammadi B, Alosco ML, Tripodis Y, Mez J, Daneshvar DH. Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts. Acta Neuropathol. 2023 Apr; 145(4):371-394. PMID: 36759368.
Read at: PubMed - Published on 1/21/2023
Nicks R, Clement NF, Alvarez VE, Tripodis Y, Baucom ZH, Huber BR, Mez J, Alosco ML, Aytan N, Cherry JD, Cormier KA, Kubilius C, Mathias R, Svirsky SE, Pothast MJ, Hildebrandt AM, Chung J, Han X, Crary JF, McKee AC, Frosch MP, Stein TD. Repetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis. Acta Neuropathol. 2023 Apr; 145(4):395-408. PMID: 36681782.
Read at: PubMed - Published on 1/20/2023
Kirsch D, Shah A, Dixon E, Kelley H, Cherry JD, Xia W, Daley S, Aytan N, Cormier K, Kubilus C, Mathias R, Alvarez VE, Huber BR, McKee AC, Stein TD. Vascular injury is associated with repetitive head impacts and tau pathology in chronic traumatic encephalopathy. J Neuropathol Exp Neurol. 2023 Jan 20; 82(2):127-139. PMID: 36617181.
Read at: PubMed - Published on 11/19/2022
Cherry JD, Baucom ZH, Eppich KG, Kirsch D, Dixon ER, Tripodis Y, Bieniek KF, Farrell K, Whitney K, Uretsky M, Crary JF, Dickson D, McKee AC. Neuroimmune proteins can differentiate between tauopathies. J Neuroinflammation. 2022 Nov 19; 19(1):278. PMID: 36403052.
Read at: PubMed - Published on 9/24/2022
Alosco ML, Su Y, Stein TD, Protas H, Cherry JD, Adler CH, Balcer LJ, Bernick C, Pulukuri SV, Abdolmohammadi B, Coleman MJ, Palmisano JN, Tripodis Y, Mez J, Rabinovici GD, Marek KL, Beach TG, Johnson KA, Huber BR, Koerte I, Lin AP, Bouix S, Cummings JL, Shenton ME, Reiman EM, McKee AC, Stern RA. Associations between near end-of-life flortaucipir PET and postmortem CTE-related tau neuropathology in six former American football players. Eur J Nucl Med Mol Imaging. 2023 01; 50(2):435-452. PMID: 36152064.
Read at: PubMed
View 39 more publications: View full profile at BUMC