Jennifer E. Snyder-Cappione , PhD

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Snyder-Cappione received her B.S. from Brandeis University and her Ph.D. from the University of Rochester Medical Center. Her doctoral research focus was the regulation of IFN-gamma and cytotoxic effector functions by CD8+ T cells. During her post-doctoral work at UCSF, she investigated the role of iNKT cells in HIV and Mycobacterium tuberculosis infections as well as sarcoidosis. Her current research interests include: (1) determining the diagnostic and prognostic potential of ex vivo immune functional profiling in human inflammatory diseases, (2) investigating the differentiation potential and lineage relationships of iNKT cell subsets, and (3) elucidating the role of T cell and iNKT cell exhaustion in the progression of infectious diseases and cancer.

Publications

  • Published 12/17/2024

    Lawton ML, Inge MM, Blum BC, Smith-Mahoney EL, Bolzan D, Lin W, McConney C, Porter J, Moore J, Youssef A, Tharani Y, Varelas X, Denis GV, Wong WW, Padhorny D, Kozakov D, Siggers T, Wuchty S, Snyder-Cappione J, Emili A. Multiomic profiling of chronically activated CD4+ T cells identifies drivers of exhaustion and metabolic reprogramming. PLoS Biol. 2024 Dec; 22(12):e3002943. PMID: 39689157.

    Read at: PubMed

  • Published 5/15/2024

    Pihl RMF, Smith-Mahoney EL, Olson A, Yuen RR, Asundi A, Lin N, Belkina AC, Snyder-Cappione JE. Vd1 Effector and Vd2 ?d T-Cell Subsets Shift in Frequency and Are Linked to Plasma Inflammatory Markers During Antiretroviral Therapy-Suppressed HIV Infection. J Infect Dis. 2024 May 15; 229(5):1317-1327. PMID: 38390982.

    Read at: PubMed

  • Published 9/29/2023

    Sabharwal V, Taglauer E, Demos R, Snyder-Cappione J, Shaik-Dasthagirisaheb YB, Parker-Kelleher S, Hunnewell J, Boateng J, Clarke K, Yuen R, Barnett ED, Wachman EM, Yarrington CD. Comparison of Anti-SARS-CoV-2-Specific Antibody Signatures in Maternal and Infant Blood after COVID-19 Infection versus COVID-19 Vaccination during Pregnancy. Am J Perinatol. 2024 May; 41(S 01):e2970-e2977. PMID: 37774748.

    Read at: PubMed

  • Published 1/29/2023

    Sabharwal V, Demos R, Snyder-Cappione J, Parker SE, Shaik-Dasthagirisaheb Y, Hunnewell J, Boateng J, Clarke K, Yuen R, Barnett E, Yarrington C, Taglauer E, Wachman EM. Cytokine levels in maternal and infant blood after COVID-19 vaccination during pregnancy in comparison with unvaccinated controls. J Reprod Immunol. 2023 Mar; 156:103821. PMID: 36764228.

    Read at: PubMed

  • Published 12/12/2022

    Wachman EM, Snyder-Cappione J, Devera J, Boateng J, Dhole Y, Clarke K, Yuen RR, Parker SE, Hunnewell J, Ferraro R, Jean-Sicard S, Woodard E, Cruikshank A, Sinha B, Bartolome R, Barnett ED, Yarrington C, Taglauer ES, Sabharwal V. Maternal, Infant, and Breast Milk Antibody Response Following COVID-19 Infection in Early Versus Late Gestation. Pediatr Infect Dis J. 2023 Mar 01; 42(3):e70-e76. PMID: 36729773.

    Read at: PubMed

View All 42 Publications:   View Full Profile in BUMC

Other Positions

  • Member, BU-BMC Cancer Center
    Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University
  • Director, Flow Cytometry Core Facility
    Boston University Chobanian & Avedisian School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Websites

Education

  • University of Rochester School of Medicine & Dentistry, PhD
  • University of Rochester School of Medicine & Dentistry, MS
  • Brandeis University, BS

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