Jennifer Elizabeth Snyder-Cappione , PhD
Assistant Professor, Virology, Immunology & Microbiology
Biography
Dr. Snyder-Cappione received her B.S. from Brandeis University and her Ph.D. from the University of Rochester Medical Center. Her doctoral research focus was the regulation of IFN-gamma and cytotoxic effector functions by CD8+ T cells. During her post-doctoral work at UCSF, she investigated the role of iNKT cells in HIV and Mycobacterium tuberculosis infections as well as sarcoidosis. Her current research interests include: (1) determining the diagnostic and prognostic potential of ex vivo immune functional profiling in human inflammatory diseases, (2) investigating the differentiation potential and lineage relationships of iNKT cell subsets, and (3) elucidating the role of T cell and iNKT cell exhaustion in the progression of infectious diseases and cancer.
Other Positions
- Member, BU-BMC Cancer Center, Boston University
- Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
- Director, Flow Cytometry Core Facility, Boston University Chobanian & Avedisian School of Medicine
- Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- University of Rochester School of Medicine & Dentistry, PhD
- University of Rochester School of Medicine & Dentistry, MS
- Brandeis University, BS
Publications
- Published on 12/17/2024
Lawton ML, Inge MM, Blum BC, Smith-Mahoney EL, Bolzan D, Lin W, McConney C, Porter J, Moore J, Youssef A, Tharani Y, Varelas X, Denis GV, Wong WW, Padhorny D, Kozakov D, Siggers T, Wuchty S, Snyder-Cappione J, Emili A. Multiomic profiling of chronically activated CD4+ T cells identifies drivers of exhaustion and metabolic reprogramming. PLoS Biol. 2024 Dec; 22(12):e3002943. PMID: 39689157.
Read at: PubMed - Published on 5/15/2024
Pihl RMF, Smith-Mahoney EL, Olson A, Yuen RR, Asundi A, Lin N, Belkina AC, Snyder-Cappione JE. Vd1 Effector and Vd2 ?d T-Cell Subsets Shift in Frequency and Are Linked to Plasma Inflammatory Markers During Antiretroviral Therapy-Suppressed HIV Infection. J Infect Dis. 2024 May 15; 229(5):1317-1327. PMID: 38390982.
Read at: PubMed - Published on 9/29/2023
Sabharwal V, Taglauer E, Demos R, Snyder-Cappione J, Shaik-Dasthagirisaheb YB, Parker-Kelleher S, Hunnewell J, Boateng J, Clarke K, Yuen R, Barnett ED, Wachman EM, Yarrington CD. Comparison of Anti-SARS-CoV-2-Specific Antibody Signatures in Maternal and Infant Blood after COVID-19 Infection versus COVID-19 Vaccination during Pregnancy. Am J Perinatol. 2024 May; 41(S 01):e2970-e2977. PMID: 37774748.
Read at: PubMed - Published on 1/29/2023
Sabharwal V, Demos R, Snyder-Cappione J, Parker SE, Shaik-Dasthagirisaheb Y, Hunnewell J, Boateng J, Clarke K, Yuen R, Barnett E, Yarrington C, Taglauer E, Wachman EM. Cytokine levels in maternal and infant blood after COVID-19 vaccination during pregnancy in comparison with unvaccinated controls. J Reprod Immunol. 2023 Mar; 156:103821. PMID: 36764228.
Read at: PubMed - Published on 12/12/2022
Wachman EM, Snyder-Cappione J, Devera J, Boateng J, Dhole Y, Clarke K, Yuen RR, Parker SE, Hunnewell J, Ferraro R, Jean-Sicard S, Woodard E, Cruikshank A, Sinha B, Bartolome R, Barnett ED, Yarrington C, Taglauer ES, Sabharwal V. Maternal, Infant, and Breast Milk Antibody Response Following COVID-19 Infection in Early Versus Late Gestation. Pediatr Infect Dis J. 2023 Mar 01; 42(3):e70-e76. PMID: 36729773.
Read at: PubMed - Published on 10/3/2022
Juttukonda LJ, Wachman EM, Boateng J, Clarke K, Snyder-Cappione J, Taglauer ES. The impact of maternal SARS-CoV-2 vaccination and first trimester infection on feto-maternal immune responses. Am J Reprod Immunol. 2022 Dec; 88(6):e13625. PMID: 36123778.
Read at: PubMed - Published on 4/21/2022
Taglauer ES, Dhole Y, Boateng J, Snyder-Cappione J, Parker SE, Clarke K, Juttukonda L, Devera J, Hunnewell J, Barnett E, Jia H, Yarrington C, Sabharwal V, Wachman EM. Evaluation of maternal-infant dyad inflammatory cytokines in pregnancies affected by maternal SARS-CoV-2 infection in early and late gestation. J Perinatol. 2022 Oct; 42(10):1319-1327. PMID: 35449446.
Read at: PubMed - Published on 6/4/2021
Olson A, Coote C, Snyder-Cappione JE, Lin N, Sagar M. HIV-1 Transcription but Not Intact Provirus Levels are Associated With Systemic Inflammation. J Infect Dis. 2021 06 04; 223(11):1934-1942. PMID: 33075121.
Read at: PubMed - Published on 4/9/2021
Yuen RR, Steiner D, Pihl RMF, Chavez E, Olson A, Smith EL, Baird LA, Korkmaz F, Urick P, Sagar M, Berrigan JL, Gummuluru S, Corley RB, Quillen K, Belkina AC, Mostoslavsky G, Rifkin IR, Kataria Y, Cappione AJ, Gao W, Lin NH, Bhadelia N, Snyder-Cappione JE. Novel ELISA Protocol Links Pre-Existing SARS-CoV-2 Reactive Antibodies With Endemic Coronavirus Immunity and Age and Reveals Improved Serologic Identification of Acute COVID-19 via Multi-Parameter Detection. Front Immunol. 2021; 12:614676. PMID: 33897682.
Read at: PubMed - Published on 5/12/2020
Bharath LP, Agrawal M, McCambridge G, Nicholas DA, Hasturk H, Liu J, Jiang K, Liu R, Guo Z, Deeney J, Apovian CM, Snyder-Cappione J, Hawk GS, Fleeman RM, Pihl RMF, Thompson K, Belkina AC, Cui L, Proctor EA, Kern PA, Nikolajczyk BS. Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation. Cell Metab. 2020 07 07; 32(1):44-55.e6. PMID: 32402267.
Read at: PubMed
View 32 more publications: View full profile at BUMC