Hanni Menn-Josephy, MD

AClinical ssociate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Menn-Josephy is a board-certified nephrologist with a special interest in Autoimmune Kidney Diseases and Lupus Nephritis. She serves as the Nephrology Director of the Lupus Multidisciplinary Program at Boston Medical Center, which operates as a regional and national referral center for patients who suffer from lupus and lupus nephritis.

Together with her colleagues, Dr. Menn-Josephy developed a unique care model that enables lupus and lupus nephritis patients to receive comprehensive care from rheumatology, nephrology, and dermatology disciplines, improving their health and reducing health-related disparities. As part of her interest in translational research in the field of lupus nephritis, Dr. Menn-Josephy, along with her colleagues, established an autoimmunity clinical registry and patient biobank with the goal of studying lupus pathogenesis to identify new therapeutic targets. As a site PI, she leads cutting-edge clinical trials including a Phase 1 study of CRISPR-Cas9-engineered T cells and a Phase 2 trial of CAR-T therapy for refractory lupus nephritis. Notably, her site recruited the first patient globally for the rapcabtagene autoleucel (CAR-T) study in January 2025.

Dr. Menn-Josephy serves as the Associate Program Director for the Nephrology Fellowship Program, where she established a coaching initiative for fellows to enhance their sense of belonging and well-being within the section. This program provides personalized mentorship and professional development opportunities, creating a supportive environment that helps fellows thrive during their specialized training.

Publications

  • Published 8/24/2024

    Siskind SM, Yadav S, Solomon M, Knapp PE, Menn-Josephy H, Francis J, Rennke HG, Ayalon R, Modzelewski KL. Nephrotic Syndrome as a Complication of Systemic Calcitonin Amyloidosis From Long-Standing Metastatic Medullary Thyroid Cancer. AACE Clin Case Rep. 2024; 10(6):244-248. PMID: 39734505.

    Read at: PubMed

  • Published 12/18/2023

    Menn-Josephy H, Hodge LS, Birardi V, Leher H. Efficacy of Voclosporin in Proliferative Lupus Nephritis with High Levels of Proteinuria. Clin J Am Soc Nephrol. 2024 Mar 01; 19(3):309-318. PMID: 38110196.

    Read at: PubMed

  • Published 2/22/2023

    Schmidt IM, Shohet M, Serrano M, Yadati P, Menn-Josephy H, Ilori T, Eneanya ND, Cleveland Manchanda EC, Waikar SS. Patients' Perspectives on Race and the Use of Race-Based Algorithms in Clinical Decision-Making: a Qualitative Study. J Gen Intern Med. 2023 Jul; 38(9):2045-2051. PMID: 36811702.

    Read at: PubMed

  • Published 6/23/2022

    Nader R, Zhen A, Angel-Korman A, Pavlovich SS, Pogrebinsky A, Doros G, Menn-Josephy H, Stern L, Sanchorawala V, Havasi A. Predictors and outcomes of acute kidney injury during autologous stem cell transplantation in AL amyloidosis. Nephrol Dial Transplant. 2022 Jun 23; 37(7):1281-1288. PMID: 34043009.

    Read at: PubMed

  • Published 6/15/2021

    Li H, Tsokos MG, Bhargava R, Adamopoulos IE, Menn-Josephy H, Stillman IE, Rosenstiel P, Jordan J, Tsokos GC. IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation. J Clin Invest. 2021 06 15; 131(12). PMID: 33956666.

    Read at: PubMed

View All 14 Publications:   View Full Profile in BUMC

Other Positions

  • Member, Amyloidosis Center
    Boston University

Websites

Education

  • Technion - Israel Institute of Technology, MD
  • Ben-Gurion University of the Negev, BSc

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