Gretchen A. Gignac, MD
Clinical Associate Professor, Medicine
Biography
I am a medical oncologist who has clinical and research expertise in genitourinary medical oncology as well as clinical trials. My clinical practice is at Boston Medical Center and includes adult patients with cancers of the prostate, kidney, bladder, testicles and penis, as well as other solid cancers. My treatment expertise is in hormonal agents, chemotherapy, immunotherapy, targeted therapies, radioactive pharmaceuticals, bone targeted therapies, supportive and palliative care. I am also an educator in the Chobanian and Avedisian School of Medicine and Boston Medical Center Hematology and Oncology Fellowship Program.
Other Positions
- Member, BU-BMC Cancer Center, Boston University
- Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
Education
- University of Pennsylvania School of Medicine, MD
- University of Rochester, BA
Publications
- Published on 3/3/2025
Beidler LB, Zayhowski K, Nahorniak M, Loo S, Gignac GA, Wang C, Gunn CM. Perceptions and Use of Germline Genetic Testing Among Patients With Prostate Cancer. JCO Oncol Pract. 2025 Mar 03; OP2400624. PMID: 40030090.
Read at: PubMed - Published on 11/29/2024
Zayhowski K, Wang C, Nahorniak M, Loo S, Gignac G, Gunn C. A qualitative study of the experiences of patients with prostate cancer when receiving negative genetic results: "I still don't have a grasp of what it all means". J Genet Couns. 2024 Nov 29. PMID: 39611226.
Read at: PubMed - Published on 3/12/2024
Khosla H, Bhatt S, Wang MJ, Gignac G, Mittal K, Patel J. Enfortumab-vedotin use for urothelial carcinoma in two patients on hemodialysis. J Oncol Pharm Pract. 2024 Jul; 30(5):941-944. PMID: 38470473.
Read at: PubMed - Published on 6/29/2023
Gunn CM, Gignac G, Hardy B, Zayhowski K, Pankowska M, Loo S, Wang C. Characterizing Referrals for Prostate Cancer Genetic Services in a Safety-Net Hospital. JCO Oncol Pract. 2023 Oct; 19(10):852-859. PMID: 37384869.
Read at: PubMed - Published on 1/1/2023
Gunn CM, Li EX, Gignac GA, Pankowska M, Loo S, Zayhowski K, Wang C. Delivering Genetic Testing for Patients with Prostate Cancer: Moving Beyond Provider Knowledge as a Barrier to Care. Cancer Control. 2023; 30:10732748221143884. PMID: 36946278.
Read at: PubMed - Published on 11/4/2022
Jafari N, Chen A, Kolla M, Pompa IR, Qiu Y, Yu R, Llevenes P, Ennis CS, Mori J, Mahdaviani K, Halpin M, Gignac GA, Heaphy CM, Monti S, Denis GV. Novel plasma exosome biomarkers for prostate cancer progression in co-morbid metabolic disease. Adv Cancer Biol Metastasis. 2022 Dec; 6. PMID: 36644690.
Read at: PubMed - Published on 6/16/2022
Quintiliani LM, Murray GF, Waite K, Salerno K, Gignac GA, Yuh D, Volandes A, Paasche-Orlow MK. "I'm in My Feelings Now": Examination of Advance Care Planning Video Declarations by People with Advanced Cancer from a Safety Net Hospital. J Palliat Med. 2023 Jan; 26(1):28-34. PMID: 35708552.
Read at: PubMed - Published on 4/11/2022
Mori JO, Shafran JS, Stojanova M, Katz MH, Gignac GA, Wisco JJ, Heaphy CM, Denis GV. Novel forms of prostate cancer chemoresistance to successful androgen deprivation therapy demand new approaches: Rationale for targeting BET proteins. Prostate. 2022 Jun; 82(10):1005-1015. PMID: 35403746.
Read at: PubMed - Published on 2/22/2020
Chua S, Qureshi MM, Boyd G, Gignac GA, Hirsch AE. Outcomes for Young Men With Localized Intermediate-Risk Prostate Cancer: An Analysis of the NCDB. Clin Genitourin Cancer. 2020 10; 18(5):e531-e542. PMID: 32220567.
Read at: PubMed - Published on 6/13/2018
Karantanos T, Karanika S, Seth B, Gignac G. The absolute lymphocyte count can predict the overall survival of patients with non-small cell lung cancer on nivolumab: a clinical study. Clin Transl Oncol. 2019 Feb; 21(2):206-212. PMID: 29948974.
Read at: PubMed
View 14 more publications: View full profile at BUMC