Gene F. Kwan, MD, MPH

Instructor, Medicine

Gene Kwan
(617) 638-8760
88 E. Newton St Newton Pavilion

Biography

I am a cardiologist and global health researcher developing expertise in the intersection between these two fields. My primary professional goal is to push the frontier of global cardiovascular disease epidemiology and health service delivery (implementation) research through the development, implementation, evaluation, improvement and dissemination of integrated chronic care programs targeted to overcome specific barriers in rural low- and middle-income countries (LMIC).

My research stems from experience in the field in rural Rwanda and Haiti since 2008 in collaboration with local Ministries of Health and the non-governmental organizations Partners In Health and Zanmi Lasante. I have developed and implemented care models using the strategy of task-shifting: training in-country nurses and generalist physicians in simplified protocols to aid in specialty care for the diagnosis and management of non-communicable diseases (NCD) including hypertension, diabetes, heart failure, stroke, and respiratory disease. My research has helped determine that heart failure in rural Rwanda and Haiti is generally from endemic causes (as opposed to coronary heart disease) and a leading cause of hospitalization. In addition, we demonstrated that nurse-directed management improves control of blood pressure for patients with hypertension and improves symptoms for those with heart failure. My long-term goal is to develop and utilize evidence-based approaches for the understanding of cardiovascular disease in LMICs and influence programmatic development, implementation and policy.

I have active academic collaborations with projects in Haiti, Rwanda, Bangladesh, and Uganda. I am one of the principal authors of the implementation guide and clinician handbook The Partners In Health Guide to Chronic Care Integration for Endemic Non-Communicable Diseases. I have presented my work at several American Heart Association conferences including the Annual Scientific Sessions, Epidemiology, Nutrition, Prevention and Metabolism, and Quality and Clinical Outcomes Research sessions. I have also been an invited speaker both nationally and in Haiti and Rwanda. I continue to serve as an Advisor for Non-Communicable Diseases at Partners In Health in Boston, Haiti and Rwanda.

Education

  • University of California, San Diego, MD
  • Harvard School of Public Health, MPH
  • University of California, Berkeley, BA

Publications

  • Published on 5/17/2017

    Roth GA, Johnson C, Abajobir A, Abd-Allah F, Abera SF, Abyu G, Ahmed M, Aksut B, Alam T, Alam K, Alla F, Alvis-Guzman N, Amrock S, Ansari H, Ärnlöv J, Asayesh H, Atey TM, Avila-Burgos L, Awasthi A, Banerjee A, Barac A, Bärnighausen T, Barregard L, Bedi N, Belay Ketema E, Bennett D, Berhe G, Bhutta Z, Bitew S, Carapetis J, Carrero JJ, Malta DC, Castañeda-Orjuela CA, Castillo-Rivas J, Catalá-López F, Choi JY, Christensen H, Cirillo M, Cooper L, Criqui M, Cundiff D, Damasceno A, Dandona L, Dandona R, Davletov K, Dharmaratne S, Dorairaj P, Dubey M, Ehrenkranz R, El Sayed Zaki M, Faraon EJA, Esteghamati A, Farid T, Farvid M, Feigin V, Ding EL, Fowkes G, Gebrehiwot T, Gillum R, Gold A, Gona P, Gupta R, Habtewold TD, Hafezi-Nejad N, Hailu T, Hailu GB, Hankey G, Hassen HY, Abate KH, Havmoeller R, Hay SI, Horino M, Hotez PJ, Jacobsen K, James S, Javanbakht M, Jeemon P, John D, Jonas J, Kalkonde Y, Karimkhani C, Kasaeian A, Khader Y, Khan A, Khang YH, Khera S, Khoja AT, Khubchandani J, Kim D, Kolte D, Kosen S, Krohn KJ, Kumar GA, Kwan GF, Lal DK, Larsson A, Linn S, Lopez A, Lotufo PA, El Razek HMA, Malekzadeh R, Mazidi M, Meier T, Meles KG, Mensah G, Meretoja A, Mezgebe H, Miller T, Mirrakhimov E, Mohammed S, Moran AE, Musa KI, Narula J, Neal B, Ngalesoni F, Nguyen G, Obermeyer CM, Owolabi M, Patton G, Pedro J, Qato D, Qorbani M, Rahimi K, Rai RK, Rawaf S, Ribeiro A, Safiri S, Salomon JA, Santos I, Santric Milicevic M, Sartorius B, Schutte A, Sepanlou S, Shaikh MA, Shin MJ, Shishehbor M, Shore H, Silva DAS, Sobngwi E, Stranges S, Swaminathan S, Tabarés-Seisdedos R, Tadele Atnafu N, Tesfay F, Thakur JS, Thrift A, Topor-Madry R, Truelsen T, Tyrovolas S, Ukwaja KN, Uthman O, Vasankari T, Vlassov V, Vollset SE, Wakayo T, Watkins D, Weintraub R, Werdecker A, Westerman R, Wiysonge CS, Wolfe C, Workicho A, Xu G, Yano Y, Yip P, Yonemoto N, Younis M, Yu C, Vos T, Naghavi M, Murray C. Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015. J Am Coll Cardiol. 2017 Jul 04; 70(1):1-25. PMID: 28527533.

    Read at: PubMed
  • Published on 2/1/2017

    Nulu S, Bukhman G, Kwan GF. Rheumatic Heart Disease: The Unfinished Global Agenda. Cardiol Clin. 2017 Feb; 35(1):165-180. PMID: 27886787.

    Read at: PubMed
  • Published on 11/1/2016

    Feinstein MJ, Bogorodskaya M, Bloomfield GS, Vedanthan R, Siedner MJ, Kwan GF, Longenecker CT. Cardiovascular Complications of HIV in Endemic Countries. Curr Cardiol Rep. 2016 Nov; 18(11):113. PMID: 27730474.

    Read at: PubMed
  • Published on 10/8/2016

    Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016 Oct 08; 388(10053):1459-1544. PMID: 27733281.

    Read at: PubMed
  • Published on 10/8/2016

    Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016 10 08; 388(10053):1545-1602. PMID: 27733282.

    Read at: PubMed
  • Published on 10/8/2016

    Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016 10 08; 388(10053):1603-1658. PMID: 27733283.

    Read at: PubMed
  • Published on 10/8/2016

    Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016 Oct 08; 388(10053):1659-1724. PMID: 27733284.

    Read at: PubMed
  • Published on 10/4/2016

    Wirtz VJ, Kaplan WA, Kwan GF, Laing RO. Response by Wirtz et al to Letter Regarding Article, "Access to Medications for Cardiovascular Diseases in Low- and Middle-Income Countries". Circulation. 2016 Oct 04; 134(14):e305-e306. PMID: 27698055.

    Read at: PubMed
  • Published on 7/14/2016

    Rahman F, Kwan GF, Benjamin EJ. Global epidemiology of atrial fibrillation. Nat Rev Cardiol. 2016 Jul 14; 13(8):501. PMID: 27411521.

    Read at: PubMed
  • Published on 6/14/2016

    Kwan GF, Mayosi BM, Mocumbi AO, Miranda JJ, Ezzati M, Jain Y, Robles G, Benjamin EJ, Subramanian SV, Bukhman G. Endemic Cardiovascular Diseases of the Poorest Billion. Circulation. 2016 Jun 14; 133(24):2561-75. PMID: 27297348.

    Read at: PubMed

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