Gareth J Morgan, PhD
Research Assistant Professor, Medicine
Biography
Gareth Morgan, PhD is a Research Assistant Professor at the Chobanian and Avedisian School of Medicine. His research focuses on the molecular mechanisms of AL amyloidosis with the aim of developing new treatments for this disease.
Other Positions
- Member, BU-BMC Cancer Center, Boston University
- Member, Amyloidosis Center, Boston University
- Member, Genome Science Institute, Boston University
- Graduate Faculty (Primary Mentor of Grad Students) , Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- University of Sheffield, PhD
- Imperial College London, BS
Publications
- Published on 12/6/2024
Morgan GJ, Nau AN, Wong S, Spencer BH, Shen Y, Hua A, Bullard MJ, Sanchorawala V, Prokaeva T. An updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis. Amyloid. 2024 Dec 06; 1-10. PMID: 39641756.
Read at: PubMed - Published on 11/18/2024
Diamond B, Chahar D, Jain MD, Poos AM, Durante M, Ziccheddu B, Kaddoura M, Papadimitriou M, Maclachlan K, Jelinek T, Davies F, Figura NB, Morgan G, Mai E, Weisel KC, Fenk R, Raab MS, Usmani S, Landgren O, Locke FL, Goldschmidt H, Schatz JH, Weinhold N, Maura F. Mutagenic impact and evolutionary influence of radiotherapy in hematologic malignancies. bioRxiv. 2024 Nov 18. PMID: 39605649.
Read at: PubMed - Published on 11/16/2024
Morgan GJ, Yung Z, Spencer BH, Sanchorawala V, Prokaeva T. Predicting Structural Consequences of Antibody Light Chain N-Glycosylation in AL Amyloidosis. Pharmaceuticals (Basel). 2024 Nov 16; 17(11). PMID: 39598451.
Read at: PubMed - Published on 10/28/2024
Klimtchuk ES, Prokaeva T, Spencer BH, Wong S, Ghosh S, Urdaneta A, Morgan G, Wales TE, Gursky O. Conformational Differences in the Light Chain Constant Domain of Immunoglobulin G and Free Light Chain May Influence Proteolysis in AL Amyloidosis. J Mol Biol. 2024 Dec 01; 436(23):168837. PMID: 39490919.
Read at: PubMed - Published on 9/15/2024
Morgan G, Nau AN, Wong S, Spencer BH, Shen Y, Hua A, Bullard MJ, Sanchorawala V, Prokaeva T. An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis. bioRxiv. 2024 Sep 15. PMID: 39314448.
Read at: PubMed - Published on 9/4/2024
Maura F, Kaddoura M, Poos AM, Baughn LB, Ziccheddu B, Bärtsch MA, Cirrincione A, Maclachlan K, Chojnacka M, Diamond B, Papadimitriou M, Blaney P, John L, Reichert P, Huhn S, Gagler D, Zhang Y, Dogan A, Lesokhin AM, Davies F, Goldschmidt H, Fenk R, Weisel KC, Mai EK, Korde N, Morgan GJ, Rajkumar SV, Kumar S, Usmani S, Landgren O, Raab MS, Weinhold N. Temporal Genomic Dynamics Shape Clinical Trajectory in Multiple Myeloma. bioRxiv. 2024 Sep 04. PMID: 39282268.
Read at: PubMed - Published on 6/21/2024
Leach BI, Ferguson JA, Morgan G, Sun X, Kroon G, Oyen D, Dyson HJ, Wright PE. Conformational Dynamics of an Amyloidogenic Intermediate of Transthyretin: Implications for Structural Remodeling and Amyloid Formation. J Mol Biol. 2024 Aug 15; 436(16):168673. PMID: 38909653.
Read at: PubMed - Published on 3/19/2024
Soszyn N, Schweigert J, Franco SR, Morgan GJ, Mitchell M, Zablah JE. Computed Tomography-Derived Normative Values of Right Ventricular Outflow Tract Structures in the Pediatric Population. Pediatr Cardiol. 2025 Mar; 46(3):562-568. PMID: 38502199.
Read at: PubMed - Published on 3/16/2024
Edwards CV, Ferri GM, Villegas-Galaviz J, Ghosh S, Bawa PS, Wang F, Klimtchuk E, Ajayi TB, Morgan GJ, Prokaeva T, Staron A, Ruberg FL, Sanchorawala V, Giadone RM, Murphy GJ. Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition. bioRxiv. 2024 Mar 16. PMID: 38558967.
Read at: PubMed - Published on 3/1/2024
Wong S, West ME, Morgan GJ. Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains. Protein Sci. 2024 Mar; 33(3):e4871. PMID: 38100259.
Read at: PubMed
View 30 more publications: View full profile at BUMC