Francesca Seta, PhD

Assistant Professor, Medicine

Francesca Seta
617.358.7814
650 Albany St Evans Biomed Research Ctr

Biography

Francesca Seta, PhD, is an Assistant Professor of Vascular Biology at the Boston University School of Medicine. Although she teaches Vascular Biology she has been trained in Pharmacology and Cardiovascular Physiology as well. Her current research is on genetic and molecular mechanisms of vascular smooth muscle function and stiffening and novel therapeutic targets for aortic aneurysms and dissections. Her research interests are Arterial Stiffness, Aortic Aneurysm/Dissection, Cardiovascular Physiology, Cardiovascular Disease Related to Metabolic Syndrome, Hypertension, Oxidative Stress, Pulmonary Hypertension, Vascular Biology, and Vascular Diseases.

Education

  • New York Medical College, PhD
  • Universit√† degli Studi "G. d'Annunzio" Chieti-Pescara, MSc
  • Universit√† degli Studi "G. d'Annunzio" Chieti-Pescara, BS

Publications

  • Published on 10/17/2018

    Yu X, Turcotte R, Seta F, Zhang Y. Micromechanics of elastic lamellae: unravelling the role of structural inhomogeneity in multi-scale arterial mechanics. J R Soc Interface. 2018 Oct 17; 15(147). PMID: 30333250.

    Read at: PubMed
  • Published on 11/20/2017

    Kohn JC, Azar J, Seta F, Reinhart-King CA. High-Fat, High-Sugar Diet-Induced Subendothelial Matrix Stiffening is Mitigated by Exercise. Cardiovasc Eng Technol. 2018 Mar; 9(1):84-93. PMID: 29159794.

    Read at: PubMed
  • Published on 11/10/2017

    Oh YS, Berkowitz DE, Cohen RA, Figueroa CA, Harrison DG, Humphrey JD, Larson DF, Leopold JA, Mecham RP, Ruiz-Opazo N, Santhanam L, Seta F, Shyy JYJ, Sun Z, Tsao PS, Wagenseil JE, Galis ZS. A Special Report on the NHLBI Initiative to Study Cellular and Molecular Mechanisms of Arterial Stiffness and Its Association With Hypertension. Circ Res. 2017 Nov 10; 121(11):1216-1218. PMID: 29122942.

    Read at: PubMed
  • Published on 10/1/2017

    Ravid K, Seta F, Center D, Waters G, Coleman D. Catalyzing Interdisciplinary Research and Training: Initial Outcomes and Evolution of the Affinity Research Collaboratives Model. Acad Med. 2017 Oct; 92(10):1399-1405. PMID: 28445220.

    Read at: PubMed
  • Published on 2/16/2017

    Shao D, Han J, Hou X, Fry J, Behring JB, Seta F, Long MT, Roy HK, Cohen RA, Matsui R, Bachschmid MM. Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. Antioxid Redox Signal. 2017 Aug 20; 27(6):313-327. PMID: 27958883.

    Read at: PubMed
  • Published on 2/7/2017

    Hu P, Wu X, Khandelwal AR, Yu W, Xu Z, Chen L, Yang J, Weisbrod RM, Lee KSS, Seta F, Hammock BD, Cohen RA, Zeng C, Tong X. Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase. Biochim Biophys Acta Mol Basis Dis. 2017 06; 1863(6):1382-1391. PMID: 28185955.

    Read at: PubMed
  • Published on 2/2/2017

    Grzegorzewska AP, Seta F, Han R, Czajka CA, Makino K, Stawski L, Isenberg JS, Browning JL, Trojanowska M. Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways. Sci Rep. 2017 02 02; 7:41605. PMID: 28150703.

    Read at: PubMed
  • Published on 9/11/2016

    Han J, Weisbrod RM, Shao D, Watanabe Y, Yin X, Bachschmid MM, Seta F, Janssen-Heininger YMW, Matsui R, Zang M, Hamburg NM, Cohen RA. The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells. Redox Biol. 2016 Oct; 9:306-319. PMID: 27693992.

    Read at: PubMed
  • Published on 8/9/2016

    Nicholson CJ, Seta F, Lee S, Morgan KG. MicroRNA-203 mimics age-related aortic smooth muscle dysfunction of cytoskeletal pathways. J Cell Mol Med. 2017 Jan; 21(1):81-95. PMID: 27502584.

    Read at: PubMed
  • Published on 7/18/2016

    Fry JL, Al Sayah L, Weisbrod RM, Van Roy I, Weng X, Cohen RA, Bachschmid MM, Seta F. Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness. Hypertension. 2016 Sep; 68(3):775-84. PMID: 27432859.

    Read at: PubMed

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