Finn Hawkins, MBBCh
Assistant Professor, Medicine
Biography
Dr. Hawkins is a Principal Investigator (P.I.) in the Center for Regenerative Medicine and The Pulmonary Center. His research focus is studying human lung development and disease using human induced pluripotent stem cells (iPSCs). Dr. Hawkins is currently using iPSC technology to study airway biology with a focus on Cystic Fibrosis.
Other Positions
- Member, Pulmonary Center, Boston University
- Member, Center for Regenerative Medicine, Boston University
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
Websites
Education
- National University of Ireland, MBBCh
Classes Taught
- GMSMM725
Publications
- Published on 10/19/2020
Hawkins FJ, Suzuki S, Beermann ML, Barillà C, Wang R, Villacorta-Martin C, Berical A, Jean JC, Le Suer J, Matte T, Simone-Roach C, Tang Y, Schlaeger TM, Crane AM, Matthias N, Huang SXL, Randell SH, Wu J, Spence JR, Carraro G, Stripp BR, Rab A, Sorsher EJ, Horani A, Brody SL, Davis BR, Kotton DN. Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2020 Oct 19. PMID: 33098807.
Read at: PubMed - Published on 9/18/2020
Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell Stem Cell. 2020 12 03; 27(6):962-973.e7. PMID: 32979316.
Read at: PubMed - Published on 9/8/2020
King NE, Suzuki S, Barillà C, Hawkins FJ, Randell SH, Reynolds SD, Stripp BR, Davis BR. Correction of Airway Stem Cells: Genome Editing Approaches for the Treatment of Cystic Fibrosis. Hum Gene Ther. 2020 Sep; 31(17-18):956-972. PMID: 32741223.
Read at: PubMed - Published on 6/30/2020
Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. bioRxiv. 2020 Jun 30. PMID: 32637964.
Read at: PubMed - Published on 6/4/2020
Abo KM, Ma L, Matte T, Huang J, Alysandratos KD, Werder RB, Mithal A, Beermann ML, Lindstrom-Vautrin J, Mostoslavsky G, Ikonomou L, Kotton DN, Hawkins F, Wilson A, Villacorta-Martin C. Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors. bioRxiv. 2020 Jun 04. PMID: 32577635.
Read at: PubMed - Published on 4/25/2020
Wang R, McCauley KB, Kotton DN, Hawkins F. Differentiation of human airway-organoids from induced pluripotent stem cells (iPSCs). Methods Cell Biol. 2020; 159:95-114. PMID: 32586451.
Read at: PubMed - Published on 2/6/2020
De Santi C, Fernández Fernández E, Gaul R, Vencken S, Glasgow A, Oglesby IK, Hurley K, Hawkins F, Mitash N, Mu F, Raoof R, Henshall DC, Cutrona MB, Simpson JC, Harvey BJ, Linnane B, McNally P, Cryan SA, MacLoughlin R, Swiatecka-Urban A, Greene CM. Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells. Mol Ther. 2020 04 08; 28(4):1190-1199. PMID: 32059764.
Read at: PubMed - Published on 1/10/2020
Mithal A, Capilla A, Heinze D, Berical A, Villacorta-Martin C, Vedaie M, Jacob A, Abo K, Szymaniak A, Peasley M, Stuffer A, Mahoney J, Kotton DN, Hawkins F, Mostoslavsky G. Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells. Nat Commun. 2020 01 10; 11(1):215. PMID: 31924806.
Read at: PubMed - Published on 11/15/2019
Jacob A, Vedaie M, Roberts DA, Thomas DC, Villacorta-Martin C, Alysandratos KD, Hawkins F, Kotton DN. Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells. Nat Protoc. 2019 12; 14(12):3303-3332. PMID: 31732721.
Read at: PubMed - Published on 10/1/2019
Ryan AL, Ikonomou L, Atarod S, Bölükbas DA, Collins J, Freishtat R, Hawkins F, Gilpin SE, Uhl FE, Uriarte JJ, Weiss DJ, Wagner DE. Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017. An Official American Thoracic Society Workshop Report. Am J Respir Cell Mol Biol. 2019 10; 61(4):429-439. PMID: 31573338.
Read at: PubMed
View 16 more publications: View full profile at BUMC