Farzad Mortazavi, PhD

Assistant Professor, Anatomy & Neurobiology

Farzad Mortazavi
617.638.4134
700 Albany St Ctr for Adv Biomed Res

Biography

Dr. Mortazavi received his B.A. in psychology from the University of South Florida, M.S at Central Michigan University, and his Ph.D. at Northeastern University in Experimental Psychology and Behavioral Neuroscience. As a postdoctoral fellow, he was a Michel J. Fox Foundation Fellow in the Department of Neurology at UCLA where his studies focused on molecular and neuroanatomical changes in neurodegenerative disorders. He is currently an Assistant Professor in the Department of Anatomy and Neurobiology and his primary research is focused on 3D farzad_2reconstruction of white-matter pathways and cortical columns using Confocal Microscopy, 2-photon Microscopy and statistical physics for analysis of these types of big data. He also collaborates with Drs. Moss, Rosene, Killiany, and Moore in the Laboratory for Cognitive Neurobiology. The laboratory focuses on the effects of normal aging on structure and function of cerebral cortex and cortical ischemia in a non-human primate model.

Dr. Mortazavi teaches the statistics course in the department of Anatomy and Neurobiology and has been training students in immunohistochemistry, cell counts and image analysis among other techniques. He is actively involved in the Forensic Anthropology program where he teaches Experimental Design and Analysis for Forensic Anthropologists.

Education

  • Northeastern University, PhD
  • Central Michigan University, MS
  • University of South Florida, BA

Classes Taught

  • AN704

Publications

  • Published on 4/1/2018

    Mortazavi F, Oblak AL, Morrison WZ, Schmahmann JD, Stanley HE, Wedeen VJ, Rosene DL. Geometric Navigation of Axons in a Cerebral Pathway: Comparing dMRI with Tract Tracing and Immunohistochemistry. Cereb Cortex. 2018 Apr 01; 28(4):1219-1232. PMID: 28203748.

    Read at: PubMed
  • Published on 3/11/2018

    Orczykowski ME, Arndt KR, Palitz LE, Kramer BC, Pessina MA, Oblak AL, Finklestein SP, Mortazavi F, Rosene DL, Moore TL. Cell based therapy enhances activation of ventral premotor cortex to improve recovery following primary motor cortex injury. Exp Neurol. 2018 Mar 11; 305:13-25. PMID: 29540323.

    Read at: PubMed
  • Published on 8/15/2017

    Mortazavi F, Romano SE, Rosene DL, Rockland KS. A Survey of White Matter Neurons at the Gyral Crowns and Sulcal Depths in the Rhesus Monkey. Front Neuroanat. 2017; 11:69. PMID: 28860975.

    Read at: PubMed
  • Published on 2/25/2017

    Shobin E, Bowley MP, Estrada LI, Heyworth NC, Orczykowski ME, Eldridge SA, Calderazzo SM, Mortazavi F, Moore TL, Rosene DL. Microglia activation and phagocytosis: relationship with aging and cognitive impairment in the rhesus monkey. Geroscience. 2017 Apr; 39(2):199-220. PMID: 28238188.

    Read at: PubMed
  • Published on 1/12/2017

    Estrada LI, Robinson AA, Amaral AC, Giannaris EL, Heyworth NC, Mortazavi F, Ngwenya LB, Roberts DE, Cabral HJ, Killiany RJ, Rosene DL. Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry. J Histochem Cytochem. 2017 Mar; 65(3):153-171. PMID: 28080173.

    Read at: PubMed
  • Published on 12/1/2016

    Richter F, Gabby L, McDowell KA, Mulligan CK, De La Rosa K, Sioshansi PC, Mortazavi F, Cely I, Ackerson LC, Tsan L, Murphy NP, Maidment NT, Chesselet MF. Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice. Neurobiol Aging. 2017 Mar; 51:54-66. PMID: 28038352.

    Read at: PubMed
  • Published on 2/22/2016

    Mortazavi F, Wang X, Rosene DL, Rockland KS. White Matter Neurons in Young Adult and Aged Rhesus Monkey. Front Neuroanat. 2016; 10:15. PMID: 26941613.

    Read at: PubMed
  • Published on 1/1/2015

    Farzad Mortazavi, Van J. Wedeen, Douglas L. Rosene. Axons and Brain Architecture; Edited by Kathleen S. Rockland. Chapter 17: Neuroanatomical Techniques for Analysis of Axonal Trajectories in the Cerebral Cortex of the Rhesus Monkey. Elsevier. Cambridge, MA. 2015; 349-366.

  • Published on 10/1/2014

    Richter F, Fleming SM, Watson M, Lemesre V, Pellegrino L, Ranes B, Zhu C, Mortazavi F, Mulligan CK, Sioshansi PC, Hean S, De La Rosa K, Khanna R, Flanagan J, Lockhart DJ, Wustman BA, Clark SW, Chesselet MF. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics. 2014 Oct; 11(4):840-56. PMID: 25037721.

    Read at: PubMed
  • Published on 4/15/2014

    Boaks A, Siwek D, Mortazavi F. The temporal degradation of bone collagen: A histochemical approach. Forensic Sci Int. 2014 Jul; 240:104-10. PMID: 24836839.

    Read at: PubMed

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