Dr. Lang, appointed as an Associate Professor of Dermatology, was recruited from the University of Chicago. Here at BU, she will continue her basic science research mission focusing on the molecular and cellular biology of melanoma. The lab’s research is centered on studying processes that occur during pigment cell development of the embryo and applying these findings toward melanoma. The premise is that pathways that are essential for development (such as growth, survival, and migration) are also important for melanoma progression (over-growth, inappropriate survival, and metastasis). She has mentored over twenty students and has served as an elected council member and plenary speaker of the Pan American Society for Pigment Cell Research.
- Member, BU-BMC Cancer Center, Boston University
- Drexel University College of Medicine, PhD
- Philadelphia University, BS
- Published on 9/10/2019
Zhai Y, Haresi AJ, Huang L, Lang D. Differences in tumor initiation and progression of melanoma in the BrafCA ;Tyr-CreERT2;Ptenf/f model between male and female mice. Pigment Cell Melanoma Res. 2020 01; 33(1):119-121. PMID: 31449725.
- Published on 1/1/2019
Lui JW, Xiao S, Ogomori K, Hammarstedt JE, Little EC, Lang D. The Efficiency of Verteporfin as a Therapeutic Option in Pre-Clinical Models of Melanoma. J Cancer. 2019; 10(1):1-10. PMID: 30662519.
- Published on 3/29/2017
Little EC, Kubic JD, Salgia R, Grippo PJ, Lang D. Canonical and alternative transcript expression of PAX6 and CXCR4 in pancreatic cancer. Oncol Lett. 2017 Jun; 13(6):4027-4034. PMID: 28588695.
- Published on 9/1/2015
Kubic JD, Little EC, Kaiser RS, Young KP, Lang D. FOXD3 Promotes PAX3 Expression in Melanoma Cells. J Cell Biochem. 2016 Feb; 117(2):533-41. PMID: 26252164.
- Published on 7/23/2015
Kubic JD, Lui JW, Little EC, Ludvik AE, Konda S, Salgia R, Aplin AE, Lang D. PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma. J Biol Chem. 2015 Sep 04; 290(36):21901-14. PMID: 26205821.
- Published on 12/22/2014
Kubic JD, Little EC, Lui JW, Iizuka T, Lang D. PAX3 and ETS1 synergistically activate MET expression in melanoma cells. Oncogene. 2015 Sep 17; 34(38):4964-74. PMID: 25531327.
- Published on 3/1/2013
Lang D, Mascarenhas JB, Shea CR. Melanocytes, melanocyte stem cells, and melanoma stem cells. Clin Dermatol. 2013 Mar-Apr; 31(2):166-78. PMID: 23438380.
- Published on 6/7/2012
Kubic JD, Mascarenhas JB, Iizuka T, Wolfgeher D, Lang D. GSK-3 promotes cell survival, growth, and PAX3 levels in human melanoma cells. Mol Cancer Res. 2012 Aug; 10(8):1065-76. PMID: 22679108.
- Published on 1/22/2010
Mascarenhas JB, Littlejohn EL, Wolsky RJ, Young KP, Nelson M, Salgia R, Lang D. PAX3 and SOX10 activate MET receptor expression in melanoma. Pigment Cell Melanoma Res. 2010 Apr; 23(2):225-37. PMID: 20067553.
- Published on 1/4/2010
Degenhardt KR, Milewski RC, Padmanabhan A, Miller M, Singh MK, Lang D, Engleka KA, Wu M, Li J, Zhou D, Antonucci N, Li L, Epstein JA. Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions. Dev Biol. 2010 Mar 15; 339(2):519-27. PMID: 20045680.
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