David Richard Pimentel, MD

Assistant Professor, Medicine

617.638.8146
650 Albany St Evans Biomed Research Ctr

Biography

Expertise includes: Oxidative modification; Exosomal communication.

Other Positions

  • Active Staff Hospital Privileges, Medicine, Boston Medical Center

Education

  • University of Maryland School of Medicine, MD
  • University of Maryland, BA

Publications

  • Published on 5/15/2019

    Luptak I, Qin F, Sverdlov A, Pimentel D, Panagia M, Croteau D, Siwik DA, Bachschmid MM, He H, Balschi JA, Colucci WS. Energetic dysfunction is mediated by mitochondrial ROS and precedes structural remodeling in metabolic heart disease. Antioxid Redox Signal. 2019 May 15. PMID: 31088291.

    Read at: PubMed
  • Published on 2/1/2018

    Luptak I, Sverdlov AL, Panagia M, Qin F, Pimentel DR, Croteau D, Siwik DA, Ingwall JS, Bachschmid MM, Balschi JA, Colucci WS. Decreased ATP production and myocardial contractile reserve in metabolic heart disease. J Mol Cell Cardiol. 2018 03; 116:106-114. PMID: 29409987.

    Read at: PubMed
  • Published on 1/11/2016

    Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc. 2016 Jan 11; 5(1). PMID: 26755553.

    Read at: PubMed
  • Published on 12/15/2014

    Brogan A, Ding Y, Pimentel DR, Sam F. Non-invasive imaging for cardiac amyloidosis - delaying the obvious? Int J Cardiol. 2014 Dec 15; 177(2):e87-9. PMID: 25456697.

    Read at: PubMed
  • Published on 8/7/2014

    Sverdlov AL, Elezaby A, Behring JB, Bachschmid MM, Luptak I, Tu VH, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Colucci WS. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. J Mol Cell Cardiol. 2015 Jan; 78:165-73. PMID: 25109264.

    Read at: PubMed
  • Published on 3/14/2014

    Qin F, Siwik DA, Pimentel DR, Morgan RJ, Biolo A, Tu VH, Kang YJ, Cohen RA, Colucci WS. Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload. Am J Physiol Heart Circ Physiol. 2014 May 15; 306(10):H1453-63. PMID: 24633550.

    Read at: PubMed
  • Published on 1/22/2014

    Shao D, Fry JL, Han J, Hou X, Pimentel DR, Matsui R, Cohen RA, Bachschmid MM. A redox-resistant sirtuin-1 mutant protects against hepatic metabolic and oxidant stress. J Biol Chem. 2014 Mar 14; 289(11):7293-306. PMID: 24451382.

    Read at: PubMed
  • Published on 7/19/2013

    Essick EE, Wilson RM, Pimentel DR, Shimano M, Baid S, Ouchi N, Sam F. Adiponectin modulates oxidative stress-induced autophagy in cardiomyocytes. PLoS One. 2013; 8(7):e68697. PMID: 23894332.

    Read at: PubMed
  • Published on 4/2/2013

    Haeussler DJ, Pimentel DR, Hou X, Burgoyne JR, Cohen RA, Bachschmid MM. Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migration. J Biol Chem. 2013 May 24; 288(21):15380-9. PMID: 23548900.

    Read at: PubMed
  • Published on 8/10/2012

    Kumar V, Calamaras TD, Haeussler D, Colucci WS, Cohen RA, McComb ME, Pimentel D, Bachschmid MM. Cardiovascular redox and ox stress proteomics. Antioxid Redox Signal. 2012 Dec 1; 17(11):1528-59. PMID: 22607061.

    Read at: PubMed

View 46 more publications: View full profile at BUMC

View all profiles