Darrell Nelson Kotton, MD

Professor, Medicine

Darrell Kotton
617.414.2969
670 Albany St Biosquare III

Biography

Expertise includes: Stem Cell Biology; iPS cells; Reprogramming; Gene Therapy; Lung Developmental Biology.

Other Positions

  • Director, Center for Regenerative Medicine, Boston University School of Medicine
  • Professor, Pathology & Laboratory Medicine, Boston University School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
  • Active Staff Privileges, Pulmonary, Allergy, Sleep & Critical Care Medicine, Medicine, Boston Medical Center

Education

  • Washington University School of Medicine, MD
  • University of Pennsylvania, BA

Publications

  • Published on 7/16/2018

    Reeves EP, O'Dwyer CA, Dunlea DM, Wormald MR, Hawkins P, Alfares M, Kotton DN, Rowe SM, Wilson AA, McElvaney NG. Ataluren, a New Therapeutic for Alpha-1 Antitrypsin Deficient Individuals with Nonsense Mutations. Am J Respir Crit Care Med. 2018 Jul 16. PMID: 30011228.

    Read at: PubMed
  • Published on 5/4/2018

    McCauley KB, Hawkins F, Kotton DN. Derivation of Epithelial-Only Airway Organoids from Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 2018 May; 45(1):e51. PMID: 30040246.

    Read at: PubMed
  • Published on 4/12/2018

    McCauley KB, Alysandratos KD, Jacob A, Hawkins F, Caballero IS, Vedaie M, Yang W, Slovik KJ, Morley M, Carraro G, Kook S, Guttentag SH, Stripp BR, Morrisey EE, Kotton DN. Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium. Stem Cell Reports. 2018 May 08; 10(5):1579-1595. PMID: 29657097.

    Read at: PubMed
  • Published on 2/5/2018

    Kotton DN. Claudin-18: unexpected regulator of lung alveolar epithelial cell proliferation. J Clin Invest. 2018 Mar 01; 128(3):903-905. PMID: 29400691.

    Read at: PubMed
  • Published on 9/28/2017

    Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, Traber K, Quinton LJ, Crane A, Davis BR, White FV, Wambach J, Whitsett JA, Cole FS, Morrisey EE, Guttentag SH, Beers MF, Kotton DN. Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells. Cell Stem Cell. 2017 Oct 05; 21(4):472-488.e10. PMID: 28965766.

    Read at: PubMed
  • Published on 9/25/2017

    Serra M, Alysandratos KD, Hawkins F, McCauley KB, Jacob A, Choi J, Caballero IS, Vedaie M, Kurmann AA, Ikonomou L, Hollenberg AN, Shannon JM, Kotton DN. Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification. Development. 2017 11 01; 144(21):3879-3893. PMID: 28947536.

    Read at: PubMed
  • Published on 9/19/2017

    Luo J, Qin L, Kural MH, Schwan J, Li X, Bartulos O, Cong XQ, Ren Y, Gui L, Li G, Ellis MW, Li P, Kotton DN, Dardik A, Pober JS, Tellides G, Rolle M, Campbell S, Hawley RJ, Sachs DH, Niklason LE, Qyang Y. Vascular smooth muscle cells derived from inbred swine induced pluripotent stem cells for vascular tissue engineering. Biomaterials. 2017 Dec; 147:116-132. PMID: 28942128.

    Read at: PubMed
  • Published on 8/15/2017

    Coleman FT, Blahna MT, Kamata H, Yamamoto K, Zabinski MC, Kramnik I, Wilson AA, Kotton DN, Quinton LJ, Jones MR, Pelton SI, Mizgerd JP. Capacity of Pneumococci to Activate Macrophage Nuclear Factor ?B: Influence on Necroptosis and Pneumonia Severity. J Infect Dis. 2017 Aug 15; 216(4):425-435. PMID: 28368460.

    Read at: PubMed
  • Published on 8/15/2017

    Rashid S, Kotton DN, Bar-Joseph Z. TASIC: determining branching models from time series single cell data. Bioinformatics. 2017 Aug 15; 33(16):2504-2512. PMID: 28379537.

    Read at: PubMed
  • Published on 6/16/2017

    Kotton D. Interview with Darrell Kotton. Regen Med. 2017 Apr; 12(4):337-338. PMID: 28621167.

    Read at: PubMed

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