Andrew J. Henderson, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Research in my laboratory focuses on cellular mechanisms that regulate HIV replication and transcription. Current projects include exploring how signaling influences HIV infection and latency, devising strategies for long-term repression of HIV provirus and characterizing the transcriptional status of HIV provirus in T cell and macrophage subsets. In addition, we are interested in mechanisms that contribute to HIV associated inflammation. I have served on NIH study sections and special emphasis panels and was a member and chair for the NIH AIDS Molecular and Cellular Biology Study Section. In addition to my research, I have always been proactive in undergraduate and graduate training and I am the current co-Director of the BU PREP post-bac program. I also have organized and participated in programs for international students including a summer program with University of Dammam, Saudi Arabia, a short course at Makerere University in Uganda and a Fogarty International Center training grant with the University of Liberia.

Publications

  • Published 5/9/2024

    Kilroy JM, Leal AA, Henderson AJ. Chronic HIV Transcription, Translation, and Persistent Inflammation. Viruses. 2024 May 09; 16(5). PMID: 38793632.

    Read at: PubMed

  • Published 2/1/2023

    Basukala B, Rossi S, Bendiks S, Gnatienko N, Patts G, Krupitsky E, Lioznov D, So-Armah K, Sagar M, Cheng C, Henderson AJ. Virally Suppressed People Living with HIV Who Use Opioids Have Diminished Latency Reversal. Viruses. 2023 Feb 01; 15(2). PMID: 36851631.

    Read at: PubMed

  • Published 6/28/2022

    Kuniholm J, Coote C, Henderson AJ. Defective HIV-1 genomes and their potential impact on HIV pathogenesis. Retrovirology. 2022 Jun 28; 19(1):13. PMID: 35764966.

    Read at: PubMed

  • Published 1/12/2022

    Dalecki AG, Greer BD, Duverger A, Strange EL, Carlin E, Wagner F, Shi B, Lowman KE, Perez M, Tidwell C, Kaczmarek Michaels K, Giattina S, Bossmann SH, Henderson AJ, Hu H, Kutsch O. Host T Cell Dedifferentiation Effects Drive HIV-1 Latency Stability. J Virol. 2022 03 09; 96(5):e0197421. PMID: 35019721.

    Read at: PubMed

  • Published 12/28/2021

    Kuniholm J, Armstrong E, Bernabe B, Coote C, Berenson A, Patalano SD, Olson A, He X, Lin NH, Fuxman Bass JI, Henderson AJ. Intragenic proviral elements support transcription of defective HIV-1 proviruses. PLoS Pathog. 2021 12; 17(12):e1009982. PMID: 34962974.

    Read at: PubMed

View All 73 Publications:   View Full Profile in BUMC

Other Positions

  • Assistant Dean, Oral Health Sciences
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
  • Associate Professor, Virology, Immunology & Microbiology
    Boston University Chobanian & Avedisian School of Medicine
  • Member, BU-BMC Cancer Center
    Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University
  • Member, Genome Science Institute
    Boston University
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
  • Co-Director, Clinical and Translational Science Institute
    Boston University

Websites

Education

  • University of California, Riverside, PhD
  • University of California, Riverside, MS
  • University of California, Riverside, BS

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