Dr. Jiang and his group reported recently that neutrophil elastase (NE) regulates vascular endothelial cell permeability.
Dr. Jiang and his group reported recently that neutrophil elastase (NE), a protease secreted from neutrophils, regulates vascular endothelial cell permeability. NE cleaves and activates protease-activated receptor-2, leading to actomyosin cytoskeletal activation, cell junction molecule VE-cadherin degradation, and increased endothelial permeability. Inhibition and deletion of NE in mice protect obesogenic diet-induced vascular leakage and immune […]
Employment Opportunity
Postdoctoral Associate Position: The Boston University School of Medicine seeks recent Ph.D. graduates with a metabolic or immunologic research background to join the Pharmacology and Whitaker Cardiovascular Institute as Post-doctoral Research Associates. The interests of the research group are focused on understanding the metabolic regulation of hematopoiesis, systemic inflammation related to obesity, fatty liver diseases, vascular […]
April 2018: Zhen Jiang MD, PhD
Recent achievements in the WCVI. Zhen Jiang MD, PhD and Jiang Lab. Spotlight article in Molecular and Cellular Biology (MCB) with editor’s comment. (Editor’s comments)(Full article) Mol. Cell. Biol.-2018-04-CDP138 (PDF version)