Boston University Medical Campus
Pulmonary, Critical Care, and Allergy Medicine

Medical School:

Internship: Indiana University

Residency: Indiana University

Chief Residency: Indiana University

Fellowship: Boston University

Board Certifications: Internal Medicine, Pulmonary Medicine, Critical Care Medicine

Special Interests:

RESEARCH:

• Alveolar Epithelial Cell Biology
• Molecular Biology of Lung Cancer

CLINICAL:

• General Pulmonary Medicine
• Critical Care Medicine
• Thoracic Oncology

Dr. Kathuria is an Assistant Professor in the Department of Medicine. She attends in the Thoracic Oncology Center and specializes in the management and work-up of thoracic tumors. She sees pulmonary at the East Boston Neighborhood Health Center .

Dr. Kathuria’s research focuses on developing a gene-expression signature, applied to histologically tumor-free lymph nodes obtained at surgical resection for curative intent in early stage NSCLC, that can guide subsequent treatment decisions to optimize patient outcomes. In addition she is interested in understanding the molecular mechanisms regulating caveolin-1 and other target genes by ETS transcription factors in lung tumor progression.

She is a member of three research groups at the Pulmonary Center , the Epithelial Group, the Pulmonomics Group and the Lung Cancer Group

Selected Publications:

1. K.A. Sloan, H.A. Marquez, Li, J, Y.X. Cao, A. Hinds, C.J, O’Hara, S. Kathuria, M.I. Ramirez, M.C. Williams, and H. Kathuria. Increased PEA3/E1AF and Decreased Net/Elk-3, both Ets Proteins, Characterize Human NSCLC Progression and Regulate Caveolin-1 Transcription in Calu-1 and NCI-H23 NSCLC Cell Lines. Carcinogenesis, in press 2009
2. Morgan, RK, Campbell-Reardon, C, Kathuria, H, Fernando, HC, Daly BDT. Pulmonary Function changes following high-dose radiation with concurrent chemotherapy prior to resection of locally advanced non-small-cell lung cancer, Annals of Thoracic Surgery, in press 2009
3. Kathuria H, Spira A, Brody J. “Genomics of Lung Cancer” in Handbook of Genomic Medicine. Elsevier Press, 2008
4. Kathuria H, Cao Y, Hinds A, Ramirez MI, Williams MC. ERM is expressed by alveolar epithelial cells in adult mouse lung and regulates caveolin-1 transcription in mouse lung epithelial cell lines. J Cell Biochem. 102(1): 13-27, 2007
5. Kathuria H, Cao YX, Ramirez MI, Williams, MC. Transcription of the caveolin-1 gene is differentially regulated in lung type I epithelial and endothelial cell lines: A role for ETS proteins in epithelial cell expression. J. Biol. Chem. 279: 30028-30036, 2004
6. Nasreen N, Mohammed KA, Hardwick J, Van Horn RD, Sanders K, Kathuria H, Loghmani F, Antony VB. Low molecular weight hyaluronon induces malignant mesothelioma (MMC) proliferation and haptotaxis: role of CD44 receptor in MMC proliferation and haptotaxis. Oncol Res. 13(2): 71-78, 2002

Links:

Thoracic Oncology Center
Lung Cancer