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Pulmonary Center News

An R61/R33 from the NIH was awarded to Professor Jay Mizgerd, Professor Tom Kepler, and Associate Professor Rachel Fearns to elucidate the lung virome. They will use B cells from human lungs as a tool to determine which viruses exert the most immunological pressure in the lower respiratory tract.

 

Alicia Wooten, a PhD student being mentored by Professor Jay Mizgerd, gave a presentation on her perspectives as a scientist-in-training who happens to be deaf at the March for Science in Boston.

 

Congratulations to Professor David Center for receiving the 2017 Breathing for Life Award from the ATS Foundation. This award is the highest honor conferred by the ATS Foundation for philanthropy, presented to individuals demonstrating consistent support for the foundation’s research agenda, inspiring philanthropic activity from others, advocating for the support of young pulmonary investigators, and raising awareness of respiratory disease.

 

Professor Darrell Kotton and colleagues report in a Cell Stem Cell paper the best ways yet to differentiate induced pluripotent stem cells into human airway cells and even organoids with characteristics of lung tissue. These new strategies have promise for modeling pulmonary diseases and screening drugs for purposes of personalized medicine or discovering new therapeutic approaches.

 

New faculty recruitment: Newly appointed as Assistant Professor of Medicine, Markus Bosmann will be moving his thriving research enterprise from the University of Mainz in Germany to our Pulmonary Center in the winter of 2017. Dr. Bosmann studies the molecular mechanisms of pulmonary immunity and inflammation, particularly during ARDS, pneumonia, sepsis, and pulmonary fibrosis.

 

New faculty recruitment: Newly appointed as an Associate Professor of Medicine, Jason Rock will be moving his thriving research enterprise from UCSF to BU’s Pulmonary Center and Center for Regenerative Medicine in summer of 2017. Dr. Rock studies the roles of stem and progenitor cells in lung development and lung repair after injury.

 

Associate Professor Lee Quinton received an R01 grant from the NIH to study liver-lung interactions during pneumonia. The proposed studies will determine whether and how transcriptional responses in hepatocytes help prevent ARDS, disseminated infection, and liver failure during severe respiratory infection.

 

Professor Jay Mizgerd received an Outstanding Investigator Award from the NHLBI, providing nearly 6 million dollars over 7 years to study the biology of pneumonia. This is the first time that the NHLBI has provided this type of award, designed to support an ongoing research program being led by an accomplished investigator rather than a single distinct research project.

 

Assistant Professor Allan Walkey received an R01 grant from the NIH to study atrial fibrillation during sepsis. After discovering how important it is to sepsis outcomes, Dr. Walkey is now generating and testing automated systems for detecting and predicting atrial fibrillation in the ICU.

 

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Elucidating the biology of healthy lungs.
Discovering mechanisms responsible for pulmonary disease.
Translating basic biology to clinical intervention.
Determining clinical efficacy.
The Pulmonary Center is dedicated to fighting lung disease.  Pulmonary Center investigators integrate their research and educational activities; share laboratory space, facilities, and staff; combine resources; and work together daily.  The Pulmonary Center strengthens the individual research programs of its investigators while generating a unified effort to combat lung disease.
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April 29, 2017
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