Previous Trainee Seminars and Journal Clubs

Spring 2017
January 9 Microbiology Journal Club Sila Ataca Briney, B. et al. 2016. Tailored Immunogens Direct Affinity Maturation Toward HIV Neutralizing Antibodies. Cell 166:1459-1470.
16 No Seminar
23 Immunology Journal Club Kyle Pedro Park, R.J. et al. 2016. A Genome-Wide CRISPR Screen Identifies a Restricted set of HIV Host Dependency Factors. Nat. Genetics [Epub ahead of print].
30 Inflammation Journal Club Christina Lisk Hutton, A.J. et al. 2017. Human Lung Fibroblasts Present Bacterial Antigens to Autologous Lung Th Cells. J. Immunol. 198:110-118.
February 6 Postdoctoral Fellow Seminars John Ruedas
(Connor Lab)
and
Sarah Shearer
(Fearns Lab)
“Common Occurrence of Tissue-Culture Adapted Ebola Viruses Caused by a Single Mutation in the Glycoprotein Fusion Loop”
and
“Initiation of Respiratory Syncytial Virus Transcription and Replication”
13 Student Seminars Molly Braun
(Fearns Lab)
and
Matthew Gagne
(Henderson Lab)
“The Multifunctional Role of a Domain in the RSV Polymerase”
and
“The Effects of Differential T Cell Stimulation on HIV Infection and Reactivation”
20 No Seminar
27 Microbiology Journal Club Rachel Yuen Deriu, E. et al. 2016. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS Pathogens 12(5): e1005572.
March 6 Immunology Journal Club Matthew Gagne Druzd, D. et al. 2017. Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses. Immunity 46:120-132.
13 Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar
20 Postdoctoral Fellow Seminar Dequina Nicholas
(Nikolajczyk Lab)
and
Judith Olejnik
(Mühlberger Lab)
“Fatty Acid Uptake Unexpectedly Supports a Th17 Cytokine Signature in Type 2 Diabetes (T2D) Inflammation”
and
“Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Response in Human Macrophages”
27 Student Seminars Tessa Cressey
(Fearns and Muhlberger Labs)
and
Ludy Registre
(Sagar Lab)
“Relating Polymerase Structure to Initiation of RNA Synthesis”
and
“CXCR4 Variants are Neutralization Resistant Compared to CCR5-Using Viruses in HIV-1B”
April 3 Microbiology Journal Club Kimberley Barker Zipperer, A. et al. 2016. Human Commensals Producing a Novel Antibiotic Impair Pathogen Colonization. Nature 353:511-529.
10 Immunology Journal Club Ian Francis Gury-BenAri, M., et al. 2016. The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome. Cell 166(5):1231-1246.
17 No Seminar
24 Student Seminars R Baer
(Galagan Lab)
and
Kyle Pedro
(Henderson Lab)
“Discovery and Characterization of a Novel Steroid-Sensing Transcription Factor from a Bacterium”
and
“The Contribution of DC-Mediated and T Cell Receptor Signaling to HIV trans-infection”
May 1 Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar
8 Postdoctoral Fellow Seminars Luis Agosto
(Henderson Lab)
and
Michael Reiser
(Wetzler Lab)
“HIV Latency after Cell-to-Cell Transmission to Restin gCD4+ T Cells”
and
“The TLR Ligand Based Adjuvant, Neisserial Porin PorB, and its Mechanism of Adjuvant Activity”
Monday
May 22 @ 10:00 a.m.
Dissertation Defense Seminar Kaitlin Sawatzki “Examination of the Immunoglobulin Repertoire Before and After Anthrax Vaccine Adsorbed Immunization”
Tuesday
May 23 @ 10:00 a.m.
Qualifying Exam Seminars Jaileene Hernandez-Escalante
and
Rachel Yuen
“Investigating the Lipid Metabolic Dysregulation of T1D Autoreactive T Cells”
and
“Investigating the Role of Adjuvants in the Development of Humoral Immunological Memory”
Thursday May 25 @ 1:00 p.m. Qualifying Exam Seminars Eric Brownhill
and
Whitney Manhart
“Macrophages in TB: A Study in Stress Management”
and
“Development of an Ebola Virus Pathogenesis Model using iPSC-Derived Hepatocytes”
Thursday June 1 @ 10:00 a.m. Qualifying Exam Seminar Sarah Nodder “Investigating Vpr-Mediated DNA Damage Responses during HIV Infection”
Fall 2016
September 26 at
11:30 AM
Microbiology Student Qualifying Exam Seminar Alexander Barron
(Browning Lab)
“Regulation of Inflammation-Stimulated Protein Transport in Dermal Fibroblasts by Doublecortin-Like Kinase 1”
October 3 Microbiology Journal Club Whitney Manhart Chuong, E.B. et al. 2016. Regulatory Evolution of Innate Immunity Through Co-Option of Endogenous Retroviruses. Science 351:1083-1087.
10 No Seminar
17 Student Seminars Michelle Fleury
(Dooms Lab)
and
Ian Francis
(Wetzler Lab)
“Characterizing Immune Dysfunction in Systemic Sclerosis”
and
“Host Response to Neisseria gonorrhoeae Infection in Female Wild Type Mice is Dictated by the Dominant Sex Hormone”
24 Inflammation Journal Club Cari Meisel Li, W.A. et al. 2016. The Effect of Surface Modification of Mesoporous Silica Micro-Rod Scaffold on Immune Cell Activation and Infiltration. Biomaterials 83:249-256.
31 Immunology Journal Club Emad Arafa Xiong, H. et al. 2016. Innate Lymphocyte/Ly6Chi Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance. Cell 165:679-689.
November 7 Student Seminars Sila Ataca
(Kepler Lab)
and
Stephanie D’Souza
(Kepler Lab)
“Biophysical Characterization of Immunoglobulins during Affinity Maturation in the Human Response to Anthrax Vaccine”
and
“Immunogenomics of the Egyptian Fruit Bat, an Important Viral Reservoir”
14 Microbiology Journal Club Sarah Nodder Muenchhoff, M et al. 2016. Nonprogressing HIV-infected Children Share Fundamental Immunological Features of Nonpathogenic SIV Infection. Sci Transl Med 8:358ra125.Supplementary Materials.
21 Postdoctoral Seminar Michelle Olsen
(Connor Lab)
and
Kristen Peters
(Connor Lab)
“Mechanisms of Ebolavirus Dependence on Polyamines and Hypusinated-eIF5A”
and
“Early Term Placental Explants as an ex vivo Model of Zika Virus Infection”
28 Inflammation Journal Club Jaileene Hernandez Bengsch, B. et al. 2016. Bioenergetic Insufficiencies due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 are an Early Driver of CD8+ T Cell Exhaustion. Immunity 45:1-16.
December 5 Sr. Research
Scientist
Hisashi Akiyama “Role of Myeloid Cells in HIV-1 Pathogenesis”
12 Immunology Journal Club Gregory Hall Meyer zu Horste, G. et al. 2016. RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression. Cell Reports 16:392-404.
Spring 2016
February 1 Microbiology Journal Club Tessa Cressey Long, J.S. et al. 2016. Species difference in ANP32A underlies influenza A virus polymerase host restriction. Nature, 529(7584), 101–104.
8 No Seminar
Friday, Feb 12 @ 12:00 PM DISSERTATION DEFENSE SEMINAR Krishna Moody “Attenuation of BCR-TLR Responses by FcγRIIB”
15 No Seminar
22 Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar
29 Student Seminars Michelle Fleury
and
Ludy Registre
“Role of Immunoregulatory Pathways in Systemic Sclerosis”
and
“Neutralization Differences Between CCR5 and CXCR4 Tropic Viruses in HIV-1B Infection”
March Friday, Mar 4 @ 12:00 PM DISSERTATION DEFENSE SEMINAR Emily Nelson “Examination of the Cellular Stress Response and Post-transcriptional Regulation of RNA during Ebola Virus Infection”
7 Inflammation Journal Club Christina Lisk Weisel, F.J. et al. 2016.  A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells. Immunity  44: 116-130.
14 No Seminar
21 Immunology Journal Club Barry Horne Lood, C., et al. 2015. Neutrophil Extracellular Traps Enriched in Oxidized Mitochondrial DNA are Interferogenic and Contribute to Lupus-like Disease. Nat. Med. 22:146-153.
Friday, Mar 25 @ 11:00 AM DISSERTATION DEFENSE SEMINAR Gregory Wasserman “A Discrete Population of Ciliated Cells Express the piRNA Binding Protein MIWI2 to Regulate Lung Inflammation”
28 Student Seminars Matthew Gagne
and
Grace Olinger
“Effects of Differential T Cell-associated Signals on HIV Infection”
and
“Investigating the Duplication Within the Attachment Glycoprotein Gene of Human Respiratory Syncytial Virus (HRSV)”
April 4 Microbiology Journal Club R Baer Westerman, A.J. et al. 2016. Dual RNA-seq Unveils Noncoding RNA Functions in Host-pathogen Interactions. Nature 529:496-501.
11 No Seminar
18 No Seminar
25 No Seminar
May 2 Inflammation Journal Club Margaret Baker Almeida et al. 2015. The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease. Immunity 43:264-276.
Thursday, May 5 @ 1:00 PM DISSERTATION DEFENSE SEMINAR Munir Mosaheb “Immunological Responses and Mechanisms of Action of the TLR2-ligand Neisserial PorB Vaccine Adjuvant”
9 Immunology Journal Club Matthew Gagne Wang, Z. et al. 2016. CRISPR/Cas9-derived Mutations both Inhibit HIV-1 Replication and Accelerate Viral Escape. Cell Reports 15:481-489.
June Wednesday,
June 1 @ 12:00 PM
Qualifying Exam Seminars Kyle Pedro “The Impact of Signaling from the Infectious Synapse on HIV-1 Infection and the Establishment of Latency”
6 Qualifying Exam Seminars R Baer
and
Molly Braun
and
Tessa Cressey
“Characterization and Directed Evolution of Hormone Sensitive Bacterial Transcription Factors for use in Biosensing Applications”
and
“Factors Affecting Viral Transcription during Respiratory Syncytial Virus Infection”
and
“Investigating Filovirus Replication and Transcription Mechanisms”
13 Trainee Travel Award Seminars Matthew Gagne
and
Kaitlin Sawatzki
Cold Spring Harbor Meeting on Retrovirus
and
Gordon Conference on Antibody Biology and Engineering
Fall 2015
September
NOTE:
Seminar is
12:00-1:30 pm
21 Microbiology Student Qualifying Exam Seminars Sila Ataca “Biophysical Characterization of Immunoglobulins during Affinity Maturation in the Human Response to Anthrax Vaccine”
Stephanie D’Souza “Immunogenomics of the Egyptian Fruit Bat, an Important Viral Reservoir”
Ian Francis “Evaluation of Neisseria gonorrhoeae outer Membrane Vesicles as a Vaccine Candidate for Gonococcal Infection using a Novel Transgenic Mouse Model”
28 Immunology Journal Club Caitlin Miller Grow E.J. et al. Intrinsic Retroviral Reactivation in Human Preimplantation Embryos and Pluripotent Cells. Nature 522(7555):221-225, 2015.
Tuesday
29 @ 11:00 AM
DISSERTATION DEFENSE Fadie Coleman “Influence of Macrophage NF-kB Activation on Pneumococcal Pneumonia”
October 5 Microbiology Journal Club Molly Braun Leung, D.W. et al. An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions. Cell Reports 11(3):376-389, 2015.
11 No Seminar
19 Research Scientist Seminar Hisashi Akiyama “Role of CD169/Siglec-1 in HIV-1 Dissemination and Evasion from Antiviral Immune Responses”
26 No Seminar
November 2 Inflammation Journal Club George Papadopoulos Warnatsch, A. et al. Neutrophil Extracellular Traps License Macrophages for Cytokine Production in Atherosclerosis. Science 349:316-320, 2015.
9 Immunology Journal Club Alexander Barron Brunham, R.D. A Chlamydia Vaccine on the Horizon. Science 348:1322-1323, 2015.Stary, G. et al. Vaccines. A Mucosal Vaccine Against Chlamydia trachomatis Generates two Waves of Protective Memory T Cells. Science 348:aaa8205
16 Student Seminars Kaitlin Sawatzki
and
Gregory Wasserman
“Non-Specific Activation of Autoreactive B Cells after Anthrax Vaccination Delays Protection”
and
“Miwi2 Exerts piRNA Independent Regulation of Innate Immunity during Bacterial Pneumonia”
23 Research Scientist Seminar Adam Hume “Marburg Virus VP35 Function in Human and Bat Cells”
30 Inflammation Journal Club Christina Lisk Gaudet, R.G. et al. Cytosolic Detection of the Bacterial Metabolite HBP Activates TIFA-Dependent Innate Immunity. Science 348:1251-1256, 2015.
December 7 No Seminar
14 No Seminar
Spring 2015
January 26 Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar
February 9 Immunology Journal Club Cancelled – Snow
16 No Seminar
23 Microbiology Journal Club Grace Olinger Hotard, A.L. et al. 2015. Identification of Residues in the Human Respiratory Syncytial Virus Fusion Protein that Modulates Fusion Activity and Pathogenesis. J. Virol. 89:512-522
March 2 Microbiology Journal Club Matthew Gagne Gardner, M.R. et al. 2015. AAV-Expressed eCD4-Ig Provides Durable Protection from Multiple SHIV Challenges. Nature [Epub ahead of print].
9 Student Seminar Kaitlin Sawatzki
(Kepler Lab)
“An Assessment of Immunoglobulin Repertoire Sequencing: Getting Real with Big Data”
16 Immunology Journal Club Raquel Rodriguez Nice, T.J. et al. 2015. Interferon-gamma Cures Persistent Murine Norovirus Infection in the Absence of Adaptive Immunity. Science 347:269-73.
23 Postdoctoral Seminar Anna Belkina
(Snyder-Cappione Lab)
“New Insights into Immune Exhaustion Using 16-Color Flow Cytometry”
30 Microbiology Journal Club Stephanie D’Souza Selinger, C. et al. 2014. Cytokine Systems Approach Demonstrates Differences in Innate and Pro-Inflammatory host Responses Between Genetically Distinct MERS-CoV Isolates. BMC Genomics 15:1161-1176.
April 6 Student Seminars Michelle Fleury
(Dooms Lab)
and
Ludy Registre
(Sagar Lab)
“Role of Immune Cell Dysfunction in Scleroderma Pathogenesis”
and
“The Role of Anti-V3 Loop Neutralizing Antibodies on the Emergence of CXCR4 Tropism in HIV-1B”
13 Microbiology Journal Club Kaitlin Sawatzki McHeyzer-Williams, L.J. et al. 2015. Class-Switched Memory B cells Remodel BCRs within Secondary Germinal Centers. Nat. Immunol. 16:296-307.
20 No Seminar
27 Postdoctoral Seminar Tathagat Ray
(Ingalls Lab)
“Cross Talk Between Complement System and Toll-like Receptors: Implication in Inflammation and Immunity”
May 4 Immunology Journal Club Alicia Wooten Li, D. et al. 2014. IL-33 Promotes ST2-Dependent Lung Fibrosis by the Induction of Alternatively Activated Macrophages and Innate Lymphoid Cells in Mice. J. Allergy Clin. Immunol.  134:1422-1432
11 Postdoctoral Seminar Luis Agosto
(Henderson Lab)
“HIV Replication in Macrophages during P. gingivalis Co-Infection”
13 DISSERTATION DEFENSE Kristie Hilliard “The Functional Significance of the Lung-Liver Axis During Pneumonia”
27 Qualifying Exam Seminars Matthew Gagne
and
Grace Olinger
and Sila Ataca
“Interrogating the Effects of Differential Signaling on HIV Transcription using a Tunable System”
and
“Investigating the Effects of Duplications within the Attachment Glycoprotein Gene of Clinically Isolated Human Respiratory Syncytial Virus (HRSV) Strains”
and
“Characterization of Antibodies during Affinity Maturation in the Human Response to Anthrax Vaccine”
July 16 10:00 AM DISSERTATION DEFENSE Suzanne Kijewski “Mechanistic Differences in Interactions of HIV-1 and HIV-2 with Dendritic Cells”
Primary teaching affiliate
of BU School of Medicine