Thomas A. Einhorn, M.D.

Chairman, Department of Orthopaedic Surgeryeinhorn

Education:

M.D., Cornell University Medical College

General field of research:

Orthopaedics

Affiliations other than medicine:

Evans Center for Interdisciplinary Biomedical Research
Research Professor, Department of Biochemistry

Contact information:

Office
720 Harrison Avenue, DOB 808

Lab
715 Albany Street, R-205
Phone: (617)-414 1663
Fax: (617)-414 1661

orl@bu.edu

Other research websites:

http://www.bumc.bu.edu/orthopaedics/orthopaedic-surgeon-faculty-listing/thomas-a-einhorn-md-professor-and-chairman/

http://www.bu.edu/orl/index.htm

Research group information

Louis C. Gerstenfeld, PhD, Director

Elise Morgan, PhD, Collaborator

Richard Marsell, Post Doc

Hidenori Matsubara, Post Doc

Jennifer Fitch, PhD Candidate

Pui Leong, PhD Candidate

Brandon Steen, MD, Resident Fellow

Kyle Alpaugh, Graduate Student

Rachel Grimes, Graduate Student

Daniel Hogan, Jr., Graduate Student

Keywords:

Fracture Healing; BMP; Regeneration; Bone; Stem Cell

Summary of research interest:

The Cell and Molecular Biology of the Repair and Regeneration of Bone and Cartilage

Recent publications:

Giannoudis PV, Kanakaris NK, and Einhorn TA.  2007.  Interaction of Bone Morphogenetic Proteins with Cells of the Osteoclast Lineage: Review of the Existing Evidence.  OSTEOPOROSIS INT.; 18: 1565-1581.  PMID: 17694399

Wan C, Gilbert SR, Wang Y, Cao X, Ramaswamy G, Jacobsen KA, Alaql ZS, Eberhardt AW, Gerstenfeld LC, Einhorn TA, Deng L, and Clemens TL.  2008.  Activation of the Hypoxia-inducible factor-1 {alpha} Pathway Accelerates Bone Regeneration. PROC NATL ACAD SCI USA; 105: 686–689.  PMID: 18184809

Ai-Aql ZS, Alagl AS, Graves DT, Gerstenfeld LC, and Einhorn, TA.  2008.  Molecular Mechanisms Controlling Bone Formation during Fracture Healing and Distraction Osteogenesis. J. DENT. RES.; 87: 107-118.  PMID: 18218835

Barnes GL, Kakar S, Vora S, Morgan EF, Gerstenfeld LC, and Einhorn, TA.  2008.  Stimulation of Fracture-Healing with Systemic Intermittent Parathyroid Hormone Treatment., J. BONE JOINT SURG.; 90A(Suppl 1): 120-127.  PMID: 18292366

Morgan EF, Mason ZD, Bishop G, Davis AD, Wigner NA, Gerstenfeld LC, and Einhorn TA.  2008.   Combined Effects of Recombinant Human BMP-7 (rhBMP-7) and Parathyroid Hormone (1-34) in Metaphyseal Bone Healing. BONE; 43: 1031-1038.  PMID: 18761113

Gerstenfeld  LC, Sacks DJ, Pelis M, Mason ZD, Graves DT, Barrero M, Ominsky MS, Kostenuik PJ, Morgan EF, and Einhorn TA.  2009.  Comparison of Effects of the Bisphosphonate Alendronate Versus the RANKL Inhibitor Denosumab on Murine Fracture Healing. J. BONE MINER. RES.; 24: 196-208.  PMID: 19016594

Bais MV, Wigner N, Young M, Toholka R, Graves DT, Morgan EF, Gerstenfeld LC, and Einhorn TA.  2009.  BMP2 Is Essential for Post Natal Osteogenesis but Not for Recruitment of Osteogenic Stem Cells. BONE; 45(2):254-66, 2009.  PMID: 19398045

Bais M, McLean J, Sebastiani P, Young M, Wigner N, Smith T, Kotton DN, Einhorn TA, and Gerstenfeld LC.  2009.  Transcriptional Analysis of Fracture Healing and the Induction of Embryonic Stem Cell-Related Genes. PLoS ONE; 4: e5393.  PMID: 19415118

Technologies available for sharing upon request:

Please inquire by sending an email to orl@bu.edu