GSI Faculty Members

Albrecht, Kenn
Primary Affiliation: Medicine, Biomedical Genetics
Research Focus: developmental genetics and genomics, mouse genetics, linkage analysis, gene discovery and characterization
Area of Interest: organogenesis, mouse models of human disease, the relationship between development and cancer, ovarian cancer, stem cells,
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Alekseyev, Yuriy
Primary Affiliation: Microarray Core
Research Focus: Director, Microarray Resource Center
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Amar, Salomon
Primary Affiliation: Dental Medicine, Perio/Oral Biology
Research Focus: Innate immunity
Area of Interest: mouse model for obesity atherosclerosis, crohn’s and RA
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Applebaum, Kate
Primary Affiliation: Public Health, Epidemiology
Research Focus: genetic epidemiology, gene-environment interaction, genome-wide association analysis
Area of Interest: cancer, diabetes, environmental and occupational exposures, endotoxin, biomarkers, immunology
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Benjamin, Emelia J
Primary Affiliation: Medicine, Cardiology/Framingham Heart Study
Research Focus: genetic epidemiology, genome-wide association analysis
Area of Interest: atrial fibrillation, inflammation
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Blusztajn, Jan Krzysztof
Primary Affiliation: Pathology, Laboratory Medicine
Research Focus: Neuroscience
Area of Interest: Epigenetic regulation of neuronal development and aging
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Bonegio, Ramon
Primary Affiliation: Medicine/Renal
Research Focus: Developmental genetics and genomics, Disease susceptibility
Area of Interest: Glomerulonephritis, Kidney development, Epithelial cell differentiation, Cell fate control
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Campion, MaryAnn Whalen
Primary Affiliation: Medicine, Genetic Counseling Program
Research Focus:
Area of Interest: genetic counseling, ethics in genetics, prenatal genetics, teratology
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Chen, Jiang-Fan

Primary Affiliation: Medicine, Neurology
Research Focus: molecular neuropharmacology, transcriptional regulation
Area of Interest: Adenosine receptor neurobiology, Parkinson’s disease, Huntington’s disease, Psychostimulant addiction, transcritional regulation
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Cohen, Herbert T
Primary Affiliation: Medicine, Medicine/Renal Section
Research Focus: cancer biology and genetics, molecular cell biology and genetics of renal epithelium, mouse genetics
Area of Interest: Renal cancer, polycystic kidney disease, kidney development
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Connor, John H.
Primary Affiliation: Medicine/Microbiology
Research Focus: viruses
Area of Interest: virus-host interaction
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Cotton, Robin W
Primary Affiliation: GMS, Biomedical Forensic Sciences, Anatomy and Neurobiology
Research Focus: Methods development/improvement for forensic DNA applications
Area of Interest: Application of STR and other genetic markers to analysis of forensic samples
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Cozier, Yvette
Primary Affiliation: Public Health, Slone Epidemiology Center
Research Focus: candidate genes, statistical genetics, gwas
Area of Interest: hypertension, sarcoidosis, cancer
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Dasgupta, Shoumita

Primary Affiliation: Medicine, Medicine/Biomedical Genetics
Research Focus: Graduate and Medical Education
Area of Interest: Teaching methods, diversity initiatives
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Demissie, Serkalem
Primary Affiliation: Public Health, Biostatistics
Research Focus: Statistical genetics, epidemiology, multivariate and interaction analyses, genome-wide association study; population stratification
Area of Interest: Plasma lipids, bone mineral density and bone geometry, biological aging
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Denis, Gerald V
Primary Affiliation: Medicine, Cancer Research Center
Research Focus: mouse models of lymphoma and leukemia, transcription, cell cycle, anti-cancer agents
Area of Interest: cancer genetics, genomic instability, tumor suppressors, hematopoietic malignancy
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DeStefano, Anita L
Primary Affiliation: Public Health, Biostatistics
Research Focus: statistical genetics, linkage analysis, genome-wide association analysis
Area of Interest: Neurological traits, Parkinson disease, Stroke, Dementia
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Dominguez, M. Isabel
Primary Affiliation: Medicine, Medicine/Hem-Onc
Research Focus: mechanism of signal transduction in embryonic development and tumorigenesis
Area of Interest: Wnt signaling, Xenopus dorsal axis formation, use of Xenopus bioassays to the study of human diseases, mouse cardiogenesis, progenitor cells, colon and breast cancer.
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Dupuis, Josée
Primary Affiliation: Public Health, Biostatistics
Research Focus: statistical genetics, robust and flexible statistical method development for linkage and genome-wide association analysis
Area of Interest: Statistical methodological development, type-2 diabetes, biomarker of inflammation
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Farrer, Lindsay A
Primary Affiliation: Medicine, Medicine/Biomedical Genetics
Research Focus: genetic epidemiology, gene discovery, complex disease genetics
Area of Interest: Alzheimer disease and dementia, hemoglobinopathies, substance dependence, macular degeneration, exceptional longevity, adult diseases
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Flynn, Maureen
Primary Affiliation: Medicine, Human Genetics
Research Focus: hereditary cancer syndromes, disparities in health
Area of Interest: genetic counseling, public health, hereditary cancer syndromes, clinical pediatric genetics
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Ghosh, Sajal
Primary Affiliation: Medicine, Cancer Research Center
Research Focus: Study of the role of non-coding viral RNA from leukemia viruses and Epstein Barr Virus in tumor development
Area of Interest: Viral Oncology, Cancer Biology, Anticancer Therapeutics
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Goldstein, Richard
Primary Affiliation: Medicine, Pediatric Infectious Diseases
Research Focus: Bacterial Pathogens: (i) evolution, phylogeny and population structure; (ii) genomics; (iii) in vivo expression, and (iv) vaccine development
Area of Interest: Areas of Interest: Streptococcus pneumoniae, Haemophilus influenzae, CF-associated Pseudomonas aeruginosa and Burkholderia cepacia, enteropathogenic Escherichia coli
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Hasturk, Hatice
Primary Affiliation: Dental Medicine, Periodontology and Oral Biology
Research Focus: Clinical research on periodontal diseases and resolution of inflammation
Area of Interest: Resolution of inflammation, relationship between periodontal inflammation and systemic diseases, novel therapeutic applications, animal models of periodontal inflammation and tissue regeneration
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Helmerhorst, Eva J
Primary Affiliation: Dental Medicine, Periodontology and Oral Biology
Research Focus: Oral fluid proteomics, enzymology, and microbiology
Area of Interest: Mass-spectrometric characterization of the post-translational processing of salivary proteins, antifungal activities
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Johnson, W. Evan
Primary Affiliation: Medicine, Computational Biomedicine
Research focus: Computational and statistical methods in personalized medicine
Area of Interest: Translational medicine, epigenomics, gene expression and regulation, cancer, ADHD, autism, rapid diagnostics
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Jun, Gyungah
Primary Affiliation: Medicine (Biomedical Genetics), Ophthalmology, Biostatitics
Research Focus: shared genetic risk factors for age-related diseases (bivariate and multivariate analysis), genome-wide linkage, genome-wide association, mutation detection, candidate gene study, database development and management
Area of Interest: Alzheimer’s disease, age-related cataract, age-related macular degeneration, diabetic nephropathy, idiopathic membranous nephropathy, breast cancer
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Kantarci, Alpdogan
Primary Affiliation: Dental Medicine, Periodontology and Oral Biology
Research Focus: inflammation, neutrophil biology
Area of Interest: Periodontal disease, diabetes, fibrosis
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Kramnik, Igor
Primary Affiliation: Medicine, Medicine/ Microbiology
Research Focus: mechanisms of innate host resistance and susceptibility to tuberculosis
Area of Interest: genetic and epigenetic control of macrophage differentiation and function,  novel methodologies for the analysis of host – pathogen interactions
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Lafyatis, Robert
Primary Affiliation: Medicine, Medicine/ Rheumatology
Research Focus: gene expression in autoimmune diseases: systemic sclerosis and systemic lupus erythematosus
Area of Interest: translational studies in systemic sclerosis, including studies of dermal and blood mononuclear cell gene epression, fibrosis, cytokines and murine models
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Lenburg, Marc
Primary Affiliation: Medicine, Pathology
Research Focus: transcriptome analysis, gene-expression biomarker discovery, data mining, management of large-scale data sets
Area of Interest: host response to tobacco exposure and other environmental toxins, cancer
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Liu, Ching-Ti
Primary Affiliation: Public Health, Biostatistics
Research Focus: statistical genetics and genomics
Area of Interest: Type 2 Diabetes, musculoskeletal traits and aging
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Liu, Pinghua
Primary Affiliation: CAS, Chemistry
Research Focus: epigenetics, natural product especially plant natural product biosynthetic gene identification and natural product production by bioengineering
Area of Interest: chemical basis of biological clock; cancer and infectious disease vaccine; metabolomics
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Lu, Weining
Primary Affiliation: Medicine, Renal/Medicine
Research Focus: human and mouse molecular genetics, kidney development, congenital anomalies of the kidney and urinary tract
Area of Interest: human gene mutations, mouse models of human disease, nephrogenesis, CAKUT, vesicoureteral reflux (VUR), chromosome abnormalities, polycystic kidney disease (PKD)
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Luo, Zhijun
Primary Affiliation: Medicine, Biochemistry
Research Focus: Protein phosphorylation and signal transduction
Area of Interest: Oncogenesis, energy metabolism
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Mahalingam, Meera
Primary Affiliation: Medicine, Dermatology
Research Focus: genomics of melanoma and atypical nevomelanocytic proliferations
Area of Interest: melanoma, atypical nevi
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McCall, Kim
Primary Affiliation: Biology
Research Focus: understanding molecular mechanisms of programmed cell death and its role in development
Area of Interest: Drosophila developmental biology, cell death, oogenesis
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Merkel, Peter
Primary Affiliation: Medicine, Medicine/Rheumatology/Clinicial Epidemiology
Research Focus: Genetic biomarkers, translational research, clinical epidemiology
Area of Interest: Vasculitis; Scleroderma
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Miller, Mark
Primary Affiliation: Medicine, Psychiatry
Research Focus: psychiatric genetics
Area of Interest: PTSD and related disorders
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Monach, Paul
Primary Affiliation: Medicine, Medicine/Rheumatology
Research Focus: association studies, candidate gene approaches
Area of Interest: Vasculitis, autoimmune diseases
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Montano, Monty
Primary Affiliation: Medicine, Medicine
Research Focus: muscle stem cell biology, host-pathogen genomics, aging science
Area of Interest: regenerative medicine, stem cell biology, muscle wasting, infectious disease pathology
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Mostoslavsky, Gustavo
Primary Affiliation: Medicine, Medicine/GI
Research Focus: stem cell biology, reprogramming, gene transfer
Area of Interest:
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Murabito, Joanne
Primary Affiliation: Medicine, Medicine/Framingham Study
Research Focus: genetic epidemiology, genome-wide association analysis
Area of Interest: Aging and age-related phenotypes, menopause, peripheral artery disease, cancer, depressive symptoms
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Myers, Richard H
Primary Affiliation: Medicine, Neurology
Research Focus: genetic epidemiology, gene discovery and characterization
Area of Interest: Mid and late life onset diseases, Huntington’s disease, Parkinson’s disease, cardiovascular disease
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Navarro, Caryn
Primary Affiliation: Medicine, Medicine/Biomedical Genetics
Research Focus: developmental genetics, drosophila genetics, cell biology, gene discovery and characterization, protein interactions
Area of Interest: cell fate specification, cell polarity, microtubule motor transport, RNA/protein localization, models for cancer and neurological disorder
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Nikolajczyk, Barbara
Primary Affiliation: Medicine, Microbiology
Research Focus: immune system in inflammatory disease; gene regulation
Area of Interest: transcription, signal transduction, inflammatory bowel disease, type 2 diabetes, periodontal disease
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O’Connor, George T.
Primary Affiliation: Medicine, Medicine/Pulmonary
Research Focus: COPD; asthma; sleep apnea; chronic lung disease; genetic epidemiology
Area of Interest:
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Oppenheim Frank G
Primary Affiliation: Dental Medicine, Periodontology & Oral Biology
Research Focus: salivary genetic polymorphisms
Area of Interest: Cariology, Peridontal Disease, Host defense mechanisms, Biofilm formation
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Pelton, Stephen I
Primary Affiliation: Medicine, Pediatric Infectious Diseases
Research Focus: bacterial recombination, virulence genes for Streptococcus pneumoniae and Haemophilus influenzae,
Area of Interest: Pneumococcal infection, Otitis Media, Vaccine Preventable Illness
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Perls, Thomas
Primary Affiliation: Medicine, Geriatrics
Research Focus: genetic epidmiology, gene discovery
Area of Interest: Aging, Extreme Longevity
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Perrine, Susan
Primary Affiliation: Cancer Center, Pediatric Hematology, Pharmacology and Experimental Therapeutics
Research Focus: Globin gene regulation, therapeutic gene regulation in hematology and oncology
Area of Interest: hemoglobin disorders, thalassemias, sickle cell disease, viral malignancies
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Ramirez, Maria I
Primary Affiliation: Medicine, Pulmonary
Research Focus: Lung development, epithelial cell differentiation
Area of Interest: Gene regulation, epigenetics
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Ravid, Katya
Primary Affiliation: Medicine, Biochemistry/Medicine
Research Focus: bone marrow stem cell development into the platelet lineage; adenosine receptor role in platelet and vascular function
Area of Interest: Mouse models for vascular disease; cell cycle control; transcriptional regulation of lineage specificaiton
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Remick, Daniel G
Primary Affiliation: Medicine, Pathology & Laboratory Medicine
Research Focus: Sepsis, inflammation, cytokines and asthma
Area of Interest: Sepsis, inflammation, cytokines and asthma
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Roche, Patricia (Winnie)
Primary Affiliation: Public Health, Health law
Research Focus: law, ethics and policy
Area of Interest: DNA/data banking for research; direct-to-consumer testing services; patient rights;
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Romney, Carla
Primary Affiliation: Medicine, Biochemistry/GMS
Research Focus: education initiatives
Area of Interest:
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Ruiz-Opazo, Nelson
Primary Affiliation: Medicine, Medicine/Molecular Medicine
Research Focus: genetics, gene polymorphisms, functional characterization, biological modeling (transgenesis)
Area of Interest: Cardiovascular diseases, learning and memory, vascular dementia, Alzheimer’s disease, gender-specific genetic determinants
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Sahin-Toth, Miklos
Primary Affiliation: Dental Medicine, Molecular and Cell Biology
Research Focus: biochemical mechanisms of genetic risk, gene discovery and characterization
Area of Interest: chronic pancreatitis
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Samuelson, John C
Primary Affiliation: Dental Medicine, Molecular and Cell Biology
Research Focus: parasitology, biochemistry, cell biology, and glycomics
Area of Interest: Entamoeba, Giardia, Trichomonas, Plasmodium, and Toxoplasma
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Sarkar, Sibaji
Primary Affiliation: Medicine, Cancer Research Center
Research Focus: Epigenetics, signal transduction,apoptosis
Area of Interest: Gene silencing, Regulation of epigenetics and signal transduction in cancer cells and platelets
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Schreiber, Barbara
Primary Affiliation: Medicine, Biochemistry
Research Focus: inflammation in atherosclerosis, role of serum amyloid A on smooth muscle cell function
Area of Interest: inflammation in atherosclerosis, smooth muscle cells, extracellular matrix, lipid metabolism
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Sebastiani, Paola
Primary Affiliation: Public Health, Biostatistics
Research Focus: statistical genetics and genomics, genome-wide association analysis, risk prediction modeling, networks
Area of Interest: aging and longevity, sickle cell anemia
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Segre, Daniel
Primary Affiliation: CAS, Bioinformatics
Research Focus: systems biology, computational genomics, evolutionary dynamics
Area of Interest: Metabolic and genetic interaction networks, microbial metabolism and regulation
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Seldin, David
Primary Affiliation: Medicine, Hematology-Oncology/Amyloid Treatment & Research Program
Research Focus: cancer genetics, genetics of systemic amyloidosis
Area of Interest:
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Seshardi, Sudha
Primary Affiliation: Medicine, Neurology
Research Focus: genetic epidemiology, Framingham Heart Study, risk factors and risk prediction
Area of Interest: Dementia, Alzheimer’s disease, Stroke, Structural and Functional Brain Aging
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Siggers, Trevor
Primary Affiliation: Biology
Research Focus: genomics and gene regulation in the immune and inflammatory systems
Area of Interest: transcription factor NF-kB
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Spanjaard, Remco
Primary Affiliation: Otolaryngology
Research Focus: Basic and translational cancer research
Area of Interest: nuclear receptor signaling, drug and biomarker discovery, nanotechnology-based diagnostics and drug delivery
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Stearns-Kurosawa, Deborah
Primary Affiliation: Medicine, Pathology & Lab Medicine
Research Focus: translational medicine, animal models of disease
Area of Interest: inflammation, sepsis, coagulation, cardiovascular disease, obesity, nonhuman primate & mouse models
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Steffen, Martin
Primary Affiliation: Medicine, Pathology and Laboratory Medicine
Research Focus: proteomics, computational biology
Area of Interest: early detection of cancer, pathogenesis of stroke
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Steinberg, Martin
Primary Affiliation: Medicine, Pediatrics, Pathology
Research Focus Sickle cell disease, inherited disorders of the erythrocyte
Area of Interest:
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Thiagalingam, Sam
Primary Affiliation: Medicine, Medicine/Biomedical Genetics
Research Focus: Cancer genetics and epigenomics, Cancer Metastasis, MMMN cancer progression model and Epigenetics
Area of Interest: Discovery of biomarkers for diagnosis & prognosis as well as for targeting for therapy of cancer. The role of Smad signaling pathway in disease progression. Epigenetic regulation of schizophrenia & bipolar disorder.
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Van Dyke, Thomas
Primary Affiliation: Dental Medicine, Oral Biology
Research Focus: regulation of inflammation
Area of Interest: models of human inflammatory disease (mouse, rabbit, minipig), Periodontal Disease, Diabetes, Cardiovascular Disease
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Wang, Catharine
Primary Affiliation: Community Health Sciences
Research Focus: genetic risk communication, genetic literacy, family history assessment, clinical utility
Area of Interest: public health genomics, cancer prevention and control,  interactive multimedia/ehealth, intervention development
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Waxman, David J
Primary Affiliation: CAS, Biology
Research Focus: genomic approaches to gene regulation
Area of Interest: growth hormone action, sexual dimorphsim of gene expression, genomic impact of endocrine disruptor chemicals, tumor systems-wide impact of chemotherapeutic and anti-angiogenic drugs
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Wise, Lauren A
Primary Affiliation: Public Health, Epidemiology
Research Focus: genetic epidemiology
Area of Interest: Reproductive outcomes (uterine fibroids)
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Wachman, Elisha M
Primary Affiliation: Medicine, Pediatrics
Research Focus: genetic epidemiology
Area of Interest: Neonatal Opioid withdrawal

Wolozin, Benjamin
Primary Affiliation: Medicine, Pharmacology
Research Focus: Pathophysiology of Neurodegeneration, cell biology, C. elegans
Area of Interest: Parkinson’s disease, Alzheimer’s disease, ALS
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Yang, Shi
Primary Affiliation: Medicine, Pathology and Lab Medicine
Research Focus: Colorectal Cancer, Breast Cancer, Epigenetics, Molecular Pathology
Area of Interest: Serrated Polyp Neoplasia Pathway in CRC. Breast Carcinogenesis in Animal model.
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Zannis, Vassilis I
Primary Affiliation: Medicine, Medicine
Research Focus: molecular genetics
Area of Interest: Molecular genetics of apolipoproteins and lipoproteins in relation to atherosclerosis and Alzheimer’s disease
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Zou, Ying S
Primary Affiliation: Medicine, Center for Human Genetics
Research Focus: telomere and telomerase
Area of Interest: Aging and Cancer
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