GSI Faculty Members


Alekseyev, Yuriy
Primary Affiliation: Microarray Core
Research Focus: Director, Microarray Resource Center

Amar, Salomon
Primary Affiliation: Dental Medicine, Perio/Oral Biology
Research Focus: Innate immunity
Area of Interest: Mouse model for obesity atherosclerosis, crohn’s and RA

Applebaum, Kate
Primary Affiliation: Public Health, Epidemiology
Research Focus: Genetic epidemiology, gene-environment interaction, genome-wide association analysis
Area of Interest: Cancer, diabetes, environmental and occupational exposures, endotoxin, biomarkers, immunology

Bais, Manish V
Primary Affiliation:
Research Focus:
Area of Interest:

Benjamin, Emelia J
Primary Affiliation: Medicine, Cardiology/Framingham Heart Study
Research Focus: Genetic epidemiology, genome-wide association analysis
Area of Interest: Atrial fibrillation, inflammation

Blusztajn, Jan Krzysztof
Primary Affiliation: Pathology, Laboratory Medicine
Research Focus: Neuroscience
Area of Interest: Epigenetic regulation of neuronal development and aging

Bonegio, Ramon
Primary Affiliation: Medicine/Renal
Research Focus: Developmental genetics and genomics, Disease susceptibility
Area of Interest: Glomerulonephritis, Kidney development, Epithelial cell differentiation, Cell fate control

Bryant, Camron
Primary Affiliation: Department of Pharmacology and Experimental Therapeutics
Research Focus: Mouse genetics, QTL mapping, genome editing, transcriptomics, systems genetics, addiction genetics, psychiatric genetics

Campion, MaryAnn Whalen
Primary Affiliation: Medicine, Genetic Counseling Program
Research Focus:
Area of Interest: Genetic counseling, ethics in genetics, prenatal genetics, teratology

Celenza, John
Primary Affiliation: CAS, Associate Professor of Biology
Research Focus: Molecular genetic approaches to studying the production of plant defense compounds and growth regulators
Area of Interest: Plant metabolism and development

Chen, Jiang-Fan
Primary Affiliation: Medicine, Neurology
Research Focus: Molecular neuropharmacology, transcriptional regulation
Area of Interest: Adenosine receptor neurobiology, Parkinson’s disease, Huntington’s disease, Psychostimulant addiction, transcritional regulation

Cifuentes, Daniel
Primary Affiliation: Medicine, Biochemistry
Research Focus: To understand how post-transcriptional regulation of RNA and proteins orchestrates development of a single cell oocyte into a whole embryo and how these mechanisms can be extrapolated to other biological transitions such as cellular reprogramming or malignant transformation
Area of Interest: Embryonic programming, developmental biology

Cohen, Herbert T
Primary Affiliation: Medicine, Medicine/Renal Section
Research Focus: Cancer biology and genetics, molecular cell biology and genetics of renal epithelium, mouse genetics
Area of Interest: Renal cancer, polycystic kidney disease, kidney development

Connor, John H.
Primary Affiliation: Medicine/Microbiology
Research Focus: Viruses
Area of Interest: Virus-host interaction

Cotton, Robin W
Primary Affiliation: GMS, Biomedical Forensic Sciences, Anatomy and Neurobiology
Research Focus: Methods development/improvement for forensic DNA applications
Area of Interest: Application of STR and other genetic markers to analysis of forensic samples

Cozier, Yvette
Primary Affiliation: Public Health, Slone Epidemiology Center
Research Focus: Candidate genes, statistical genetics, GWAS
Area of Interest: Hypertension, sarcoidosis, cancer


Dasgupta, Shoumita
Primary Affiliation: Medicine, Medicine/Biomedical Genetics
Research Focus: Graduate and Medical Education
Area of Interest: Teaching methods, diversity initiatives

Demissie, Serkalem
Primary Affiliation: Public Health, Biostatistics
Research Focus: Statistical genetics, epidemiology, multivariate and interaction analyses, genome-wide association study; population stratification
Area of Interest: Plasma lipids, bone mineral density and bone geometry, biological aging

Denis, Gerald V
Primary Affiliation: Medicine, Cancer Research Center
Research Focus: Mouse models of lymphoma and leukemia, transcription, cell cycle, anti-cancer agents
Area of Interest: Cancer genetics, genomic instability, tumor suppressors, hematopoietic malignancy

DeStefano, Anita L
Primary Affiliation: Public Health, Biostatistics
Research Focus: Statistical genetics, linkage analysis, genome-wide association analysis
Area of Interest: Neurological traits, Parkinson disease, Stroke, Dementia

Dominguez, M. Isabel
Primary Affiliation: Medicine, Medicine/Hem-Onc
Research Focus: Mechanism of signal transduction in embryonic development and tumorigenesis
Area of Interest: Wnt signaling, Xenopus dorsal axis formation, use of Xenopus bioassays to the study of human diseases, mouse cardiogenesis, progenitor cells, colon and breast cancer.

Dupuis, Josée
Primary Affiliation: Public Health, Biostatistics
Research Focus: Statistical genetics, robust and flexible statistical method development for linkage and genome-wide association analysis
Area of Interest: Statistical methodological development, type-2 diabetes, biomarker of inflammation

Farrer, Lindsay A
Primary Affiliation: Medicine, Medicine/Biomedical Genetics
Research Focus: Genetic epidemiology, gene discovery, complex disease genetics
Area of Interest: Alzheimer disease and dementia, hemoglobinopathies, substance dependence, macular degeneration, exceptional longevity, adult diseases

Feng, Hui
Primary Affiliation: Department of Phramacology
Research Focus: Zebrafish Genetics and Cancer Therapeutics
Area of Interest: MYC-driven cancers, T-cell leukemia, neuroblastoma, and breast cancer

Flynn, Maureen
Primary Affiliation: Medicine, Human Genetics
Research Focus: Hereditary cancer syndromes, disparities in health
Area of Interest: Genetic counseling, public health, hereditary cancer syndromes, clinical pediatric genetics

Grishok, Alla

Primary Affiliation: Medicine, Biochemistry
Research Focus: new mechanisms of gene regulation by short RNAs and chromatin-modifying complexes
Area of Interest: Gene regulation by RNA and chromatin

Genco, Caroline Attardo
Primary Affiliation: Department of Medicine
Research Focus: Research in Dr. Genco’s laboratory spans basic, translational, and global health.  Areas of focus include the effects of chronic infections on systemic health, sexually transmitted infections, and respiratory infectious diseases. Her translational work has encompassed clinical studies evaluating immunological responses following acute inflammatory diseases in both a US chort and patients in Nanjing, China. Recent studies are utilizing RNA seq analysis to define both host and bacterial gene expression profiles during natural infection.
Area of Interest: Microbial gene regulation, microbiome, and gene expression profiling in human and mouse tissues

Ghosh, Sajal
Primary Affiliation: Medicine, Cancer Research Center
Research Focus: Study of the role of non-coding viral RNA from leukemia viruses and Epstein Barr Virus in tumor development
Area of Interest: Viral Oncology, Cancer Biology, Anticancer Therapeutics

Gilmore, Thomas
Primary Affiliation: Biology
Research Focus: Molecular and cellular biology
Area of Interest: NF-kappaB, signal transduction, evolution,  molecular ecology, cancer, lymphoma, immunity, drug screening

Goldstein, Richard
Primary Affiliation: Medicine, Pediatric Infectious Diseases
Research Focus: Bacterial Pathogens: (i) evolution, phylogeny and population structure; (ii) genomics; (iii) in vivo expression, and (iv) vaccine development
Area of Interest: Areas of Interest: Streptococcus pneumoniae, Haemophilus influenzae, CF-associated Pseudomonas aeruginosa and Burkholderia cepacia, enteropathogenic Escherichia coli

Hasturk, Hatice
Primary Affiliation: Dental Medicine, Periodontology and Oral Biology
Research Focus: Clinical research on periodontal diseases and resolution of inflammation
Area of Interest: Resolution of inflammation, relationship between periodontal inflammation and systemic diseases, novel therapeutic applications, animal models of periodontal inflammation and tissue regeneration

Helmerhorst, Eva J
Primary Affiliation: Dental Medicine, Periodontology and Oral Biology
Research Focus: Oral fluid proteomics, enzymology, and microbiology
Area of Interest: Mass-spectrometric characterization of the post-translational processing of salivary proteins, antifungal activities

Ikonomou, Laertis
Primary Affiliation: Center for Regenerative Medicine of Boston University and Boston Medical Center
Research focus: Pluripotent Stem Cell Biology and Stem Cell Engineering

Johnson, W. Evan
Primary Affiliation: Medicine, Computational Biomedicine
Research focus: Computational and statistical methods in personalized medicine
Area of Interest: Translational medicine, epigenomics, gene expression and regulation, cancer, ADHD, autism, rapid diagnostics

Jones, Matthew
Primary Affiliation: Medicine
Research Focus: Pneumonia biology, post-transcriptional gene regulation and non-coding RNA

Jun, Gyungah
Primary Affiliation: Medicine (Biomedical Genetics), Ophthalmology, Biostatitics
Research Focus: Shared genetic risk factors for age-related diseases (bivariate and multivariate analysis), genome-wide linkage, genome-wide association, mutation detection, candidate gene study, database development and management
Area of Interest: Alzheimer’s disease, age-related cataract, age-related macular degeneration, diabetic nephropathy, idiopathic membranous nephropathy, breast cancer

Kantarci, Alpdogan
Primary Affiliation: Dental Medicine, Periodontology and Oral Biology
Research Focus: Inflammation, neutrophil biology
Area of Interest: Periodontal disease, diabetes, fibrosis

Kepler, Thomas
Primary Affiliation: Microbiology
Research Focus: Computational Immunology

Kotton, Darrell
Primary Affiliation: Department of Medicine; Center for Regenerative Medicine
Research Focus: Stem Cell Biology; Lung Injury and Repair

Kramnik, Igor
Primary Affiliation: Medicine, Medicine/ Microbiology
Research Focus: Mechanisms of innate host resistance and susceptibility to tuberculosis
Area of Interest: Genetic and epigenetic control of macrophage differentiation and function,  novel methodologies for the analysis of host – pathogen interactions

Lafyatis, Robert
Primary Affiliation: Medicine, Medicine/ Rheumatology
Research Focus: Gene expression in autoimmune diseases: systemic sclerosis and systemic lupus erythematosus
Area of Interest: Translational studies in systemic sclerosis, including studies of dermal and blood mononuclear cell gene epression, fibrosis, cytokines and murine models

Labunskyy, Vyacheslav
Primary Affiliation: Medicine, Dermatology
Research Focus: Aging, genomics, bioinformatics, systems biology
Area of Interest: Molecular mechanisms of aging, post-transcriptional gene regulation during aging, next-generation sequencing, ribosome profiling

Lau, Nelson
Primary Affiliation: Biochemistry
Research Focus: Transposable element regulation, RNAi, regulatory RNAs, gene silencing

Lenburg, Marc
Primary Affiliation: Medicine, Pathology
Research Focus: Transcriptome analysis, gene-expression biomarker discovery, data mining, management of large-scale data sets
Area of Interest: Host response to tobacco exposure and other environmental toxins, cancer

Levin, David
Primary Affiliation: Department of Molecular & Cell Biology, Goldman School of Dental Medicine
Research Focus: Pathways of stress-induced signal transduction using yeast as a model genetic system

Liu, Ching-Ti
Primary Affiliation: Public Health, Biostatistics
Research Focus: Statistical genetics and genomics
Area of Interest: Type 2 Diabetes, musculoskeletal traits and aging

Liu, Pinghua
Primary Affiliation: CAS, Chemistry
Research Focus: Epigenetics, natural product especially plant natural product biosynthetic gene identification and natural product production by bioengineering
Area of Interest: Chemical basis of biological clock; cancer and infectious disease vaccine; metabolomics

Lu, Weining
Primary Affiliation: Medicine, Renal/Medicine
Research Focus: Human and mouse molecular genetics, kidney development, congenital anomalies of the kidney and urinary tract
Area of Interest: Human gene mutations, mouse models of human disease, nephrogenesis, CAKUT, vesicoureteral reflux (VUR), chromosome abnormalities, polycystic kidney disease (PKD)

Luo, Zhijun
Primary Affiliation: Medicine, Biochemistry
Research Focus: Protein phosphorylation and signal transduction
Area of Interest: Oncogenesis, energy metabolism

Mahalingam, Meera
Primary Affiliation: Medicine, Dermatology
Research Focus: Genomics of melanoma and atypical nevomelanocytic proliferations
Area of Interest: Melanoma, atypical nevi

McCall, Kim
Primary Affiliation: Biology
Research Focus: Understanding molecular mechanisms of programmed cell death and its role in development
Area of Interest: Drosophila developmental biology, cell death, oogenesis

Merkel, Peter
Primary Affiliation: Medicine, Medicine/Rheumatology/Clinicial Epidemiology
Research Focus: Genetic biomarkers, translational research, clinical epidemiology
Area of Interest: Vasculitis; Scleroderma

Miller, Mark
Primary Affiliation: Medicine, Psychiatry
Research Focus: Psychiatric genetics
Area of Interest: PTSD and related disorders

Monach, Paul
Primary Affiliation: Medicine, Medicine/Rheumatology
Research Focus: Association studies, candidate gene approaches
Area of Interest: Vasculitis, autoimmune diseases

Monti, Stefano
Primary Affiliation: Section of Computational Biomedicine, School of Medicine
Research Focus: Computational Biology and Cancer Genomics

Mostoslavsky, Gustavo
Primary Affiliation: Medicine, Medicine/GI
Research Focus: Stem cell biology, reprogramming, gene transfer
Area of Interest:

Murabito, Joanne
Primary Affiliation: Medicine, Medicine/Framingham Study
Research Focus: Genetic epidemiology, genome-wide association analysis
Area of Interest: Aging and age-related phenotypes, menopause, peripheral artery disease, cancer, depressive symptoms

Myers, Richard H
Primary Affiliation: Medicine, Neurology
Research Focus: Genetic epidemiology, gene discovery and characterization
Area of Interest: Mid and late life onset diseases, Huntington’s disease, Parkinson’s disease, cardiovascular disease

Nikolajczyk, Barbara
Primary Affiliation: Medicine, Microbiology
Research Focus: Immune system in inflammatory disease; gene regulation
Area of Interest: Transcription, signal transduction, inflammatory bowel disease, type 2 diabetes, periodontal disease

O’Connor, George T.
Primary Affiliation: Medicine, Medicine/Pulmonary
Research Focus: COPD; asthma; sleep apnea; chronic lung disease; genetic epidemiology
Area of Interest:

Oppenheim, Frank G
Primary Affiliation: Dental Medicine, Periodontology & Oral Biology
Research Focus: Salivary genetic polymorphisms
Area of Interest: Cariology, Peridontal Disease, Host defense mechanisms, Biofilm formation

Peloso, Gina
Primary Affiliation: Biostatistics
Research Focus: Statistical genetics, genome-wide association studies, exome sequencing
Area of Interest: Cardiovascular disease risk factors

Pelton, Stephen I
Primary Affiliation: Medicine, Pediatric Infectious Diseases
Research Focus: Bacterial recombination, virulence genes for Streptococcus pneumoniae and Haemophilus influenzae,
Area of Interest: Pneumococcal infection, Otitis Media, Vaccine Preventable Illness

Perls, Thomas
Primary Affiliation: Medicine, Geriatrics
Research Focus: Genetic epidmiology, gene discovery
Area of Interest: Aging, Extreme Longevity

Perissi, Valentina
Primary Affiliation: Medicine, Biochemistry
Research Focus: How different inputs are integrated and translated in fine-tuning of transcriptional regulation via the action of signal transduction pathways, ubiquitin conjugating machineries and chromatin remodeling enzymes
Area of Interest: Inflammation and metabolism, transcription, ubiquitin signaling

Perrine, Susan
Primary Affiliation: Cancer Center, Pediatric Hematology, Pharmacology and Experimental Therapeutics
Research Focus: Globin gene regulation, therapeutic gene regulation in hematology and oncology
Area of Interest: Hemoglobin disorders, thalassemias, sickle cell disease, viral malignancies

Ramirez, Maria I
Primary Affiliation: Medicine, Pulmonary
Research Focus: Lung development, epithelial cell differentiation
Area of Interest: Gene regulation, epigenetics

Ravid, Katya
Primary Affiliation: Medicine, Biochemistry/Medicine
Research Focus: Bone marrow stem cell development into the platelet lineage; adenosine receptor role in platelet and vascular function
Area of Interest: Mouse models for vascular disease; cell cycle control; transcriptional regulation of lineage specificaiton

Remick, Daniel G
Primary Affiliation: Medicine, Pathology & Laboratory Medicine
Research Focus: Sepsis, inflammation, cytokines and asthma
Area of Interest: Sepsis, inflammation, cytokines and asthma

Roche, Patricia (Winnie)
Primary Affiliation: Public Health, Health law
Research Focus: Law, ethics and policy
Area of Interest: DNA/data banking for research; direct-to-consumer testing services; patient rights;

Romney, Carla
Primary Affiliation: Medicine, Biochemistry/GMS
Research Focus: Education initiatives
Area of Interest:

Ruiz-Opazo, Nelson
Primary Affiliation: Medicine, Medicine/Molecular Medicine
Research Focus: Genetics, gene polymorphisms, functional characterization, biological modeling (transgenesis)
Area of Interest: Cardiovascular diseases, learning and memory, vascular dementia, Alzheimer’s disease, gender-specific genetic determinants

Russek, Shelley
Primary Affiliation: Pharmacology and Experimental Therapeutics, Neuroscience
Research Focus: Molecular Neuroscience and Neuropharmacology
Area of Interest: Plasticity of Genomic Networks that control Brain Development and Disease

Sahin-Toth, Miklos
Primary Affiliation: Dental Medicine, Molecular and Cell Biology
Research Focus: Biochemical mechanisms of genetic risk, gene discovery and characterization
Area of Interest: Chronic pancreatitis

Samuelson, John C
Primary Affiliation: Dental Medicine, Molecular and Cell Biology
Research Focus: Parasitology, biochemistry, cell biology, and glycomics
Area of Interest: Entamoeba, Giardia, Trichomonas, Plasmodium, and Toxoplasma

Sarkar, Sibaji
Primary Affiliation: Medicine, Cancer Research Center
Research Focus: Epigenetics, signal transduction,apoptosis
Area of Interest: Gene silencing, Regulation of epigenetics and signal transduction in cancer cells and platelets

Schreiber, Barbara
Primary Affiliation: Medicine, Biochemistry
Research Focus: Inflammation in atherosclerosis, role of serum amyloid A on smooth muscle cell function
Area of Interest: Inflammation in atherosclerosis, smooth muscle cells, extracellular matrix, lipid metabolism

Sebastiani, Paola
Primary Affiliation: Public Health, Biostatistics
Research Focus: Statistical genetics and genomics, genome-wide association analysis, risk prediction modeling, networks
Area of Interest: Aging and longevity, sickle cell anemia

Segre, Daniel
Primary Affiliation: CAS, Bioinformatics
Research Focus: Systems biology, computational genomics, evolutionary dynamics
Area of Interest: Metabolic and genetic interaction networks, microbial metabolism and regulation

Seldin, David
Primary Affiliation: Medicine, Hematology-Oncology/Amyloid Treatment & Research Program
Research Focus: Cancer genetics, genetics of systemic amyloidosis
Area of Interest:

Seshardi, Sudha
Primary Affiliation: Medicine, Neurology
Research Focus: Genetic epidemiology, Framingham Heart Study, risk factors and risk prediction
Area of Interest: Dementia, Alzheimer’s disease, Stroke, Structural and Functional Brain Aging

Seta, Francesca
Primary Affiliation: Department of Medicine, Vascular Biology Section
Research Focus: Vascular diseases including: cardiovascular complications of metabolic syndrome, arterial stiffness, hypertension, atherosclerosis and aortic dissection/aneurysm
Area of Interest: Molecular mechanisms of arterial disease; role of genetic and epigenetic regulation in affecting vascular cells and their function

Siggers, Trevor
Primary Affiliation: Biology
Research Focus: Genomics and gene regulation in the immune and inflammatory systems
Area of Interest: Transcription factor NF-kB

Singh, Anurag
Primary Affiliation: Medicine, Pharmacology
Research Focus: Cancer biology and pharmacogenomics
Area of Interest: Mitogenic/oncogenic signaling networks in solid malignancies and targeted therapeutics

Spira, Avi
Primary Affiliation: Medicine, Computational Biomedicine
Research Focus: Genomics/Bioinformatics, Lung exposure and disease biology, Airway “Field of Injury”, gene expression biomarker discovery

Stearns-Kurosawa, Deborah
Primary Affiliation: Medicine, Pathology & Lab Medicine
Research Focus: Translational medicine, animal models of disease
Area of Interest: Inflammation, sepsis, coagulation, cardiovascular disease, obesity, nonhuman primate & mouse models

Steffen, Martin
Primary Affiliation: Medicine, Pathology and Laboratory Medicine
Research Focus: Proteomics, computational biology
Area of Interest: Early detection of cancer, pathogenesis of stroke

Steinberg, Martin
Primary Affiliation: Medicine, Pediatrics, Pathology
Research Focus Sickle cell disease, inherited disorders of the erythrocyte
Area of Interest:

Thiagalingam, Sam
Primary Affiliation: Medicine, Medicine/Biomedical Genetics
Research Focus: Cancer genetics and epigenomics, Cancer Metastasis, MMMN cancer progression model and Epigenetics
Area of Interest: Discovery of biomarkers for diagnosis & prognosis as well as for targeting for therapy of cancer; the role of Smad signaling pathway in disease progression;m epigenetic regulation of schizophrenia & bipolar disorder.

Tolan, Dean
Primary Affiliation: CAS, Biology
Research Focus: Genomic approaches to genetic disease
Area of Interest: Inborn errors in metabolism, biochemistry and genetic analysis, carbohydrate metabolism, obesity and metabolic syndrome

Van Dyke, Thomas
Primary Affiliation: Dental Medicine, Oral Biology
Research Focus: Regulation of inflammation
Area of Interest: Models of human inflammatory disease (mouse, rabbit, minipig), Periodontal Disease, Diabetes, Cardiovascular Disease

Wang, Alice
Primary Affiliation: Division of Neonatology, Department of Pediatrics, School of Medicine
Research Focus: Basic/translational research
Area of Interest: Studying the environmental effects on the placenta, specifically cigarette smoking, opiate exposure, gestational diabetes, and preeclampsia

Wang, Catharine
Primary Affiliation: Community Health Sciences
Research Focus: Genetic risk communication, genetic literacy, family history assessment, clinical utility
Area of Interest: Public health genomics, cancer prevention and control,  interactive multimedia/ehealth, intervention development

Waxman, David J
Primary Affiliation: CAS, Biology
Research Focus: Genomic approaches to gene regulation
Area of Interest: Growth hormone action, sexual dimorphsim of gene expression, genomic impact of endocrine disruptor chemicals, tumor systems-wide impact of chemotherapeutic and anti-angiogenic drugs

Wise, Lauren A
Primary Affiliation: Public Health, Epidemiology
Research Focus: Genetic epidemiology
Area of Interest: Reproductive outcomes (uterine fibroids)

Wachman, Elisha M
Primary Affiliation: Medicine, Pediatrics
Research Focus: Genetic epidemiology
Area of Interest: Neonatal Opioid withdrawal

Wolozin, Benjamin
Primary Affiliation: Medicine, Pharmacology
Research Focus: Pathophysiology of Neurodegeneration, cell biology, C. elegans
Area of Interest: Parkinson’s disease, Alzheimer’s disease, ALS

Yang, Shi
Primary Affiliation: Medicine, Pathology and Lab Medicine
Research Focus: Colorectal Cancer, Breast Cancer, Epigenetics, Molecular Pathology
Area of Interest: Serrated Polyp Neoplasia Pathway in CRC. Breast Carcinogenesis in Animal model.

Yu, Jun
Primary Affiliation: Department of Biochemistry, School of Medicine
Research Focus: Pulmonary arterial hypertension
Area of Interest: PDGF, VEGF and endothelin signal transduction in pulmonary vascular smooth muscle cells

Zannis, Vassilis I
Primary Affiliation: Medicine, Medicine
Research Focus: Molecular genetics
Area of Interest: Molecular genetics of apolipoproteins and lipoproteins in relation to atherosclerosis and Alzheimer’s disease

Zou, Ying S
Primary Affiliation: Medicine, Center for Human Genetics
Research Focus: Telomere and telomerase
Area of Interest: Aging and Cancer