William Edward Boden, MD

Professor, Medicine

William Boden
150 South Huntington Avenue


I am ABIM board-certified in both Internal Medicine and the subspecialty of Cardiovascular Disease. Since 1979, I have held university appointments at Brown University, Wayne State University, Tufts New England Medical Center, Boston University, the University of Connecticut, State University of New York in Buffalo, and Albany Medical College. For the past 27 consecutive years, I have held leadership roles as either a Chief of cardiology or Chief of Medicine at both federal VA facilities and in the academic private sector, all of which have had strong affiliations with their respective academic health centers. In 2016, I re-joined the VA Boston MAVERIC Center as the Scientific Director, Clinical Trials Network, for the VA New England Healthcare System, and as the Research Lead Physician, for VISN 1.

I have extensive prior experience in clinical trials and comparative effectiveness research, and have served in a leadership capacity in several important national and international clinical trials, including as Study Chair for VA CSP-funded VANQWISH and COURAGE Trials, as Study Co-Chair of the NIH-funded AIM-HIGH Trial, and as a national co-PI for the NIH-funded ISCHEMIA Trial. My principal research interests include studies in stable ischemic heart disease, post-MI secondary prevention, acute coronary syndromes, and preventive cardiology.

Other Positions

  • Lecturer in Medicine, Harvard Medical School
  • Physician Research Lead & Scientific Director, Clinical Trials Network, MAVERIC Center, VA Boston Healthcare System


  • State University of New York at Brockport, MD
  • Le Moyne College, BS


  • Published on 5/26/2019

    Lyubarova R, Albers JJ, Marcovina SM, Yao Y, McBride R, Topliceanu A, Anderson T, Fleg JL, Desvigne-Nickens P, Kashyap ML, McGovern ME, Boden WE. Effects of Extended-Release Niacin on Quartile Lp-PLA2 Levels and Clinical Outcomes in Statin-treated Patients with Established Cardiovascular Disease and Low Baseline Levels of HDL-Cholesterol: Post Hoc Analysis of the AIM HIGH Trial. J Cardiovasc Pharmacol Ther. 2019 May 26; 1074248419852955. PMID: 31131629.

    Read at: PubMed
  • Published on 5/23/2019

    Koutroumpakis E, Gosmanova EO, Stahura H, Jou S, Alreshq R, Ata A, Sidhu MS, Philbin E, Boden WE, Lyubarova R. Attainment of Guideline-Directed Medical Treatment in Stable Ischemic Heart Disease Patients With and Without Chronic Kidney Disease. Cardiovasc Drugs Ther. 2019 May 23. PMID: 31123935.

    Read at: PubMed
  • Published on 4/30/2019

    Mancini GBJ, Maron DJ, Hartigan PM, Spertus JA, Kostuk WJ, Berman DS, Teo KK, Weintraub WS, Boden WE. Lifestyle, Glycosylated Hemoglobin A1c, and Survival Among Patients With Stable Ischemic Heart Disease and Diabetes. J Am Coll Cardiol. 2019 Apr 30; 73(16):2049-2058. PMID: 31023428.

    Read at: PubMed
  • Published on 2/27/2019

    Hochman JS, Reynolds HR, Bangalore S, O'Brien SM, Alexander KP, Senior R, Boden WE, Stone GW, Goodman SG, Lopes RD, Lopez-Sendon J, White HD, Maggioni AP, Shaw LJ, Min JK, Picard MH, Berman DS, Chaitman BR, Mark DB, Spertus JA, Cyr DD, Bhargava B, Ruzyllo W, Wander GS, Chernyavskiy AM, Rosenberg YD, Maron DJ. Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial. JAMA Cardiol. 2019 Feb 27. PMID: 30810700.

    Read at: PubMed
  • Published on 2/26/2019

    Rasalingam R, Boden WE. Role of Ranolazine in Reducing Angina, Subsequent Revascularization, and Healthcare Expenditures in Stable Ischemic Heart Disease. Am J Cardiol. 2019 May 15; 123(10):1729-1731. PMID: 30922541.

    Read at: PubMed
  • Published on 2/5/2019

    Farkouh ME, Sidhu MS, Brooks MM, Vlachos H, Boden WE, Frye RL, Hartigan P, Siami FS, Bittner VA, Chaitman BR, Mancini GBJ, Fuster V. Impact of Chronic Kidney Disease on Outcomes of Myocardial Revascularization in Patients With Diabetes. J Am Coll Cardiol. 2019 Feb 05; 73(4):400-411. PMID: 30704571.

    Read at: PubMed
  • Published on 2/1/2019

    Wadhera RK, Sukul D, Secemsky EA, Shen C, Gurm HS, Boden WE, Yeh RW. Temporal Trends in Unstable Angina Diagnosis Codes for Outpatient Percutaneous Coronary Interventions. JAMA Intern Med. 2019 Feb 01; 179(2):259-261. PMID: 30556822.

    Read at: PubMed
  • Published on 2/1/2019

    Weintraub WS, Hartigan PM, Mancini GBJ, Teo KK, Maron DJ, Spertus JA, Chaitman BR, Shaw LJ, Berman D, Boden WE. Effect of Coronary Anatomy and Myocardial Ischemia on Long-Term Survival in Patients with Stable Ischemic Heart Disease. Circ Cardiovasc Qual Outcomes. 2019 Feb; 12(2):e005079. PMID: 30773025.

    Read at: PubMed
  • Published on 11/6/2018

    Maron DJ, Mancini GBJ, Hartigan PM, Spertus JA, Sedlis SP, Kostuk WJ, Berman DS, Teo KK, Weintraub WS, Boden WE. Healthy Behavior, Risk Factor Control, and Survival in the COURAGE Trial. J Am Coll Cardiol. 2018 Nov 06; 72(19):2297-2305. PMID: 30384885.

    Read at: PubMed
  • Published on 8/28/2018

    Boden WE, Bhatt DL. Will COMPASS Point to a New Direction in Thrombotic Risk Reduction in Patients With Stable Cardiovascular Disease? Circulation. 2018 Aug 28; 138(9):858-860. PMID: 30354448.

    Read at: PubMed

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