Sachiko Homma, PhD

Research Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Sachiko Homma Takayama, PhD, is a Research Assistant Professor of Neurology at the Chobanian and Avedisian School of Medicine. For her research, she has received funding from many organizations including Friends of FSH Research for researching the roles of molecular chaperones and the ubiquitin-proteasome system in skeletal muscle diseases. She has made new discoveries in the medical field including having identified a new pathway of myogenic cell death in myofibrillar myopathy.

Publications

  • Published 10/15/2026

    Zhou H, Terbeck L, Berical A, Brunet M, Lange SM, Anderson JR, Olbrich H, Bracht DC, Wohlgemuth K, Rieck C, Raidt J, Klingauf J, Sutharsan S, Mussaffi H, Prais D, Dunphy V, Homma ST, Guichard P, Hamel V, Hawkins FJ, Omran H, Brown A. In situ structure of the human ciliary transition zone links linker defects to primary ciliary dyskinesia. Science. 2026 Oct 15; 394(6821):eaei5957. PMID: 42721274.

    Read at: PubMed

  • Published 7/24/2026

    Wang X, Wang Y, Yuan R, Smith GR, Ruf-Zamojski F, Homma ST, Sealfon SC, Zhou L. FAP-derived CCL2 is required for adequate monocyte/macrophage infiltration to support acute skeletal muscle injury repair. iScience. 2026 Aug 21; 29(8):116933. PMID: 42564426.

    Read at: PubMed

  • Published 7/31/2025

    Wallman DJ, Homma ST, Finton M, Beermann M, Jacob A, Choksi SP, Pletcher SD, Xu H, Bawa PS, Reiter JF, Horani A, Brody SL, Berical A, Hawkins FJ. A stem cell-based platform for functional analysis of genetic variants in lung disease. bioRxiv. 2025 Jul 31. PMID: 40766356.

    Read at: PubMed

  • Published 3/11/2025

    Wang Y, Wang X, Alabdullatif S, Homma ST, Alekseyev YO, Zhou L. Expansion and pathogenic activation of skeletal muscle-resident macrophages in mdx5cv/Ccr2-/- mice. Proc Natl Acad Sci U S A. 2025 Mar 18; 122(11):e2410095122. PMID: 40067893.

    Read at: PubMed

  • Published 6/28/2024

    Homma ST, Wang X, Frere JJ, Gower AC, Zhou J, Lim JK, tenOever BR, Zhou L. Respiratory SARS-CoV-2 Infection Causes Skeletal Muscle Atrophy and Long-Lasting Energy Metabolism Suppression. Biomedicines. 2024 Jun 28; 12(7). PMID: 39062017.

    Read at: PubMed

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Websites

Education

  • Otsuma Women's University, PhD
  • University of Tsukuba, BS

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