Gustavo Mostoslavsky, MD, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Expertise includes: Stem cells; Induced Pluripotent Stem cells (iPSC); Gene transfer and Gene editing; Lentiviruses; Disease modeling; Intestinal organoids; Neural differentiation; Immune relevant cell differentiation.

Publications

  • Published 5/15/2025

    Flores EY, Mithal A, Bawa P, Wang F, D'Amico A, O'Connell AK, Gertje HP, Tseng AE, Crossland NA, Alekseyev Y, Mostoslavsky G. Human induced pluripotent stem cell derived gut organoids recapitulate regional specific genetic programs and a role for cAMP in lineage specification. Cell Mol Gastroenterol Hepatol. 2025 May 15; 101534. PMID: 40381917.

    Read at: PubMed

  • Published 9/26/2024

    Gojanovich AD, Le NTT, Mercer RCC, Park S, Wu B, Anane A, Vultaggio JS, Mostoslavsky G, Harris DA. Abnormal synaptic architecture in iPSC-derived neurons from a multi-generational family with genetic Creutzfeldt-Jakob disease. Stem Cell Reports. 2024 Oct 08; 19(10):1474-1488. PMID: 39332406.

    Read at: PubMed

  • Published 11/28/2023

    Yeung AK, Villacorta-Martin C, Lindstrom-Vautrin J, Belkina AC, Vanuytsel K, Dowrey TW, Ysasi AB, Bawa P, Wang F, Vrbanac V, Mostoslavsky G, Balazs AB, Murphy GJ. De novo hematopoiesis from the fetal lung. Blood Adv. 2023 Nov 28; 7(22):6898-6912. PMID: 37729429.

    Read at: PubMed

  • Published 11/3/2022

    Heinze D, Park S, McCracken A, Haratianfar M, Lindstrom J, Villacorta-Martin C, Mithal A, Wang F, Yang MW, Murphy G, Mostoslavsky G. Notch activation during early mesoderm induction modulates emergence of the T/NK cell lineage from human iPSCs. Stem Cell Reports. 2022 Dec 13; 17(12):2610-2628. PMID: 36332629.

    Read at: PubMed

  • Published 9/8/2022

    Scoon WA, Mancio-Silva L, Suder EL, Villacorta-Martin C, Lindstrom-Vautrin J, Bernbaum JG, Mazur S, Johnson RF, Olejnik J, Flores EY, Mithal A, Wang F, Hume AJ, Kaserman JE, March-Riera S, Wilson AA, Bhatia SN, Mühlberger E, Mostoslavsky G. Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes. Stem Cell Reports. 2022 Oct 11; 17(10):2286-2302. PMID: 36084636.

    Read at: PubMed

Other Positions

  • Professor, Virology, Immunology & Microbiology
    Boston University Chobanian & Avedisian School of Medicine
  • Member, Pulmonary Center
    Boston University
  • Co-Director, Center for Regenerative Medicine
    Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
  • Member, Genome Science Institute
    Boston University

Education

  • Universidad Nacional de Tucumán, MD
  • The Hebrew University of Jerusalem, PhD