Catherine E. Costello, PhD

William Fairfield Warren Distinguished Professor, Biochemistry

Catherine Costello
(617) 638-6490
670 Albany St Biosquare III

Biography

Catherine Costello came to Boston University in 1994. That year she established the Center for Biomedical Mass Spectrometry, which has become an internationally recognized research center. She holds her primary appointment in the MED Biochemistry Department, with secondary appointments in the Department of Physiology & Biophysics and the Department of Chemistry. Her research, which focuses on determining the structures and functions of biologically important polymers, has revolutionized an important area of biochemistry by providing insights into the structures of molecules responsible for human disease. She is the author or co-author of more than 300 scientific papers, serves on a number of editorial boards of major journals, and has received numerous awards and honors, including the 2010 Field and Franklin Award from the American Chemical Society, one of the highest honors in her field.

Other Positions

  • Research Professor, Physiology & Biophysics, Boston University School of Medicine
  • Director, Center for Biomedical Mass Spectrometry, Boston University School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences

Education

  • Emmanuel College, AB
  • Georgetown University, MS
  • Georgetown University, PhD

Publications

  • Published on 11/18/2016

    Pianta A, Arvikar S, Strle K, Drouin EE, Wang Q, Costello CE, Steere AC. Evidence for Immune Relevance of Prevotella copri, a Gut Microbe, in Patients with Rheumatoid Arthritis. Arthritis Rheumatol. 2016 Nov 18. PMID: 27863183.

    Read at: PubMed
  • Published on 11/9/2016

    Wang YH, Meyer RD, Bondzie PA, Jiang Y, Rahimi I, Rezazadeh K, Mehta M, Laver NM, Costello CE, Rahimi N. IGPR-1 Is Required for Endothelial Cell-Cell Adhesion and Barrier Function. J Mol Biol. 2016 Nov 9. PMID: 27838321.

    Read at: PubMed
  • Published on 10/31/2016

    Villar RF, Patel J, Weaver GC, Kanekiyo M, Wheatley AK, Yassine HM, Costello CE, Chandler KB, McTamney PM, Nabel GJ, McDermott AB, Mascola JR, Carr SA, Lingwood D. Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation. Sci Rep. 2016 Oct 31; 6:36298. PMID: 27796362.

    Read at: PubMed
  • Published on 10/11/2016

    Wang Q, Drouin EE, Yao C, Zhang J, Huang Y, Leon DR, Steere AC, Costello CE. Immunogenic HLA-DR-Presented Self-Peptides Identified Directly from Clinical Samples of Synovial Tissue, Synovial Fluid, or Peripheral Blood in Patients with Rheumatoid Arthritis or Lyme Arthritis. J Proteome Res. 2016 Oct 11. PMID: 27726376.

    Read at: PubMed
  • Published on 9/23/2016

    Bandini G, Haserick JR, Motari E, Ouologuem DT, Lourido S, Roos DS, Costello CE, Robbins PW, Samuelson J. O-fucosylated glycoproteins form assemblies in close proximity to the nuclear pore complexes of Toxoplasma gondii. Proc Natl Acad Sci U S A. 2016 Oct 11; 113(41):11567-11572. PMID: 27663739.

    Read at: PubMed
  • Published on 9/21/2016

    Struwe WB, Agravat S, Aoki-Kinoshita KF, Campbell MP, Costello CE, Dell A. The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets. Glycobiology. 2016 Sep; 26(9):907-910. PMID: 27654115.

    Read at: PubMed
  • Published on 6/2/2016

    Ma J, Banerjee P, Whelan SA, Liu T, Wei AC, Ramirez-Correa G, McComb ME, Costello CE, O'Rourke B, Murphy A, Hart GW. Comparative Proteomics Reveals Dysregulated Mitochondrial O-GlcNAcylation in Diabetic Hearts. J Proteome Res. 2016 Jul 1; 15(7):2254-64. PMID: 27213235.

    Read at: PubMed
  • Published on 5/26/2016

    Zhang Z, Costa FC, Tan EP, Bushue N, DiTacchio L, Costello CE, McComb ME, Whelan SA, Peterson KR, Slawson C. O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2ß Protein at the A?-Globin Promoter. J Biol Chem. 2016 Jul 22; 291(30):15628-40. PMID: 27231347.

    Read at: PubMed
  • Published on 4/21/2016

    Premasiri WR, Lee JC, Sauer-Budge A, Théberge R, Costello CE, Ziegler LD. The biochemical origins of the surface-enhanced Raman spectra of bacteria: a metabolomics profiling by SERS. Anal Bioanal Chem. 2016 Jul; 408(17):4631-47. PMID: 27100230.

    Read at: PubMed
  • Published on 4/18/2016

    Lucena MC, Carvalho-Cruz P, Donadio JL, Oliveira IA, de Queiroz RM, Marinho-Carvalho MM, Sola-Penna M, de Paula IF, Gondim KC, McComb ME, Costello CE, Whelan SA, Todeschini AR, Dias WB. Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation. J Biol Chem. 2016 Jun 17; 291(25):12917-29. PMID: 27129262.

    Read at: PubMed

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