Catherine E. Costello, PhD

Research Professor, Physiology & Biophysics

Catherine Costello
617.358.2433
670 Albany St Biosquare III

Biography

Catherine Costello came to Boston University in 1994. That year she established the Center for Biomedical Mass Spectrometry, which has become an internationally recognized research center. She holds her primary appointment in the MED Biochemistry Department, with secondary appointments in the Department of Physiology & Biophysics and the Department of Chemistry. Her research, which focuses on determining the structures and functions of biologically important polymers, has revolutionized an important area of biochemistry by providing insights into the structures of molecules responsible for human disease. She is the author or co-author of more than 300 scientific papers, serves on a number of editorial boards of major journals, and has received numerous awards and honors, including the 2010 Field and Franklin Award from the American Chemical Society, one of the highest honors in her field.

Other Positions

  • William Fairfield Warren Distinguished Professor, Biochemistry, Boston University School of Medicine
  • Director, Center for Biomedical Mass Spectrometry, Boston University School of Medicine
  • Member, BU-BMC Cancer Center, Boston University
  • Member, Amyloidosis Center, Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
  • Member, Genome Science Institute, Boston University

Education

  • Georgetown University, PhD
  • Georgetown University, MS
  • Emmanuel College, AB

Publications

  • Published on 6/18/2020

    Azab E, Chandler KB, Uda Y, Sun N, Hussein A, Shuwaikan R, Lu V, Costello CE, McComb ME, Divieti Pajevic P. Osteocytes control myeloid cell proliferation and differentiation through Gsa-dependent and -independent mechanisms. FASEB J. 2020 Jun 18. PMID: 32557809.

    Read at: PubMed
  • Published on 6/14/2020

    Fuzita FJ, Chandler KB, Haserick JR, Terra WR, Ferreira C, Costello CE. N-glycosylation in Spodoptera frugiperda (Lepidoptera: Noctuidae) midgut membrane-bound glycoproteins. Comp Biochem Physiol B Biochem Mol Biol. 2020 Jun 14; 110464. PMID: 32553552.

    Read at: PubMed
  • Published on 3/23/2020

    Chandler KB, Alamoud KA, Stahl VL, Nguyen BC, Kartha VK, Bais MV, Nomoto K, Owa T, Monti S, Kukuruzinska MA, Costello CE. ß-Catenin/CBP inhibition alters epidermal growth factor receptor fucosylation status in oral squamous cell carcinoma. Mol Omics. 2020 06 01; 16(3):195-209. PMID: 32203567.

    Read at: PubMed
  • Published on 12/24/2019

    Wei J, Tang Y, Bai Y, Zaia J, Costello CE, Hong P, Lin C. Toward Automatic and Comprehensive Glycan Characterization by Online PGC-LC-EED MS/MS. Anal Chem. 2020 01 07; 92(1):782-791. PMID: 31829560.

    Read at: PubMed
  • Published on 10/26/2019

    Yura Y, Chong BSH, Johnson RD, Watanabe Y, Tsukahara Y, Ferran B, Murdoch CE, Behring JB, McComb ME, Costello CE, Janssen-Heininger YMW, Cohen RA, Bachschmid MM, Matsui R. Endothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice. FASEB J. 2019 12; 33(12):14147-14158. PMID: 31647879.

    Read at: PubMed
  • Published on 10/1/2019

    Tsybin YO, Bondarenko PV, Artaev VB, Zubarev RA, Costello CE. The Russian Mass Spectrometry Interest Group at ASMS: Over 20 Years of Science and Water Polo. J Am Soc Mass Spectrom. 2019 Oct 01; 30(10):2178-2182. PMID: 31951721.

    Read at: PubMed
  • Published on 8/7/2019

    Tsybin YO, Bondarenko PV, Artaev VB, Zubarev RA, Costello CE. The Russian Mass Spectrometry Interest Group at ASMS: Over 20 Years of Science and Water Polo. J Am Soc Mass Spectrom. 2019 Oct; 30(10):2178-2182. PMID: 31392702.

    Read at: PubMed
  • Published on 7/15/2019

    Chandler KB, Leon DR, Kuang J, Meyer RD, Rahimi N, Costello CE. N-Glycosylation regulates ligand-dependent activation and signaling of vascular endothelial growth factor receptor 2 (VEGFR2). J Biol Chem. 2019 08 30; 294(35):13117-13130. PMID: 31308178.

    Read at: PubMed
  • Published on 6/28/2019

    Sorvillo N, Mizurini DM, Coxon C, Martinod K, Tilvawala R, Cherpokova D, Salinger AJ, Seward RJ, Staudinger C, Weerapana E, Shapiro NI, Costello CE, Thompson PR, Wagner DD. Plasma Peptidylarginine Deiminase IV Promotes VWF-Platelet String Formation and Accelerates Thrombosis After Vessel Injury. Circ Res. 2019 Aug 16; 125(5):507-519. PMID: 31248335.

    Read at: PubMed
  • Published on 6/5/2019

    Brown Chandler K, Costello CE, Rahimi N. Glycosylation in the Tumor Microenvironment: Implications for Tumor Angiogenesis and Metastasis. Cells. 2019 Jun 05; 8(6). PMID: 31195728.

    Read at: PubMed

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