Catherine E. Costello, PhD

William Fairfield Warren Distinguished Professor, Biochemistry

Catherine Costello
(617) 638-6490
670 Albany St Biosquare III

Biography

Catherine Costello came to Boston University in 1994. That year she established the Center for Biomedical Mass Spectrometry, which has become an internationally recognized research center. She holds her primary appointment in the MED Biochemistry Department, with secondary appointments in the Department of Physiology & Biophysics and the Department of Chemistry. Her research, which focuses on determining the structures and functions of biologically important polymers, has revolutionized an important area of biochemistry by providing insights into the structures of molecules responsible for human disease. She is the author or co-author of more than 300 scientific papers, serves on a number of editorial boards of major journals, and has received numerous awards and honors, including the 2010 Field and Franklin Award from the American Chemical Society, one of the highest honors in her field.

Other Positions

  • Research Professor, Physiology & Biophysics, Boston University School of Medicine
  • Director, Center for Biomedical Mass Spectrometry, Boston University School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences

Education

  • Emmanuel College, AB
  • Georgetown University, MS
  • Georgetown University, PhD

Publications

  • Published on 4/7/2017

    Pianta A, Arvikar S, Strle K, Drouin EE, Wang Q, Costello CE, Steere AC. Evidence of the Immune Relevance of Prevotella copri, a Gut Microbe, in Patients With Rheumatoid Arthritis. Arthritis Rheumatol. 2017 May; 69(5):964-975. PMID: 27863183.

    Read at: PubMed
  • Published on 3/30/2017

    Glaskin RS, Khatri K, Wang Q, Zaia J, Costello CE. Construction of a Database of Collision Cross Section Values for Glycopeptides, Glycans, and Peptides Determined by IM-MS. Anal Chem. 2017 Apr 18; 89(8):4452-4460. PMID: 28323417.

    Read at: PubMed
  • Published on 2/8/2017

    Haserick JR, Leon DR, Samuelson J, Costello CE. Asparagine-Linked Glycans of Cryptosporidium parvum Contain a Single Long Arm, Are Barely Processed in the Endoplasmic Reticulum (ER) or Golgi, and Show a Strong Bias for Sites with Threonine. Mol Cell Proteomics. 2017 Apr; 16(4 suppl 1):S42-S53. PMID: 28179475.

    Read at: PubMed
  • Published on 12/29/2016

    Chandler KB, Leon DR, Meyer RD, Rahimi N, Costello CE. Site-Specific N-Glycosylation of Endothelial Cell Receptor Tyrosine Kinase VEGFR-2. J Proteome Res. 2017 Feb 03; 16(2):677-688. PMID: 27966990.

    Read at: PubMed
  • Published on 11/22/2016

    Liu Y, McBride R, Stoll M, Palma AS, Silva L, Agravat S, Aoki-Kinoshita KF, Campbell MP, Costello CE, Dell A, Haslam SM, Karlsson NG, Khoo KH, Kolarich D, Novotny MV, Packer NH, Ranzinger R, Rapp E, Rudd PM, Struwe WB, Tiemeyer M, Wells L, York WS, Zaia J, Kettner C, Paulson JC, Feizi T, Smith DF. The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data. Glycobiology. 2016 Nov 22. PMID: 27993942.

    Read at: PubMed
  • Published on 11/9/2016

    Wang YH, Meyer RD, Bondzie PA, Jiang Y, Rahimi I, Rezazadeh K, Mehta M, Laver NM, Costello CE, Rahimi N. IGPR-1 Is Required for Endothelial Cell-Cell Adhesion and Barrier Function. J Mol Biol. 2016 Dec 04; 428(24 Pt B):5019-5033. PMID: 27838321.

    Read at: PubMed
  • Published on 11/7/2016

    Wang Q, Drouin EE, Yao C, Zhang J, Huang Y, Leon DR, Steere AC, Costello CE. Immunogenic HLA-DR-Presented Self-Peptides Identified Directly from Clinical Samples of Synovial Tissue, Synovial Fluid, or Peripheral Blood in Patients with Rheumatoid Arthritis or Lyme Arthritis. J Proteome Res. 2017 Jan 06; 16(1):122-136. PMID: 27726376.

    Read at: PubMed
  • Published on 10/31/2016

    Villar RF, Patel J, Weaver GC, Kanekiyo M, Wheatley AK, Yassine HM, Costello CE, Chandler KB, McTamney PM, Nabel GJ, McDermott AB, Mascola JR, Carr SA, Lingwood D. Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation. Sci Rep. 2016 Oct 31; 6:36298. PMID: 27796362.

    Read at: PubMed
  • Published on 9/23/2016

    Bandini G, Haserick JR, Motari E, Ouologuem DT, Lourido S, Roos DS, Costello CE, Robbins PW, Samuelson J. O-fucosylated glycoproteins form assemblies in close proximity to the nuclear pore complexes of Toxoplasma gondii. Proc Natl Acad Sci U S A. 2016 Oct 11; 113(41):11567-11572. PMID: 27663739.

    Read at: PubMed
  • Published on 9/21/2016

    Struwe WB, Agravat S, Aoki-Kinoshita KF, Campbell MP, Costello CE, Dell A, Ten Feizi, Haslam SM, Karlsson NG, Khoo KH, Kolarich D, Liu Y, McBride R, Novotny MV, Packer NH, Paulson JC, Rapp E, Ranzinger R, Rudd PM, Smith DF, Tiemeyer M, Wells L, York WS, Zaia J, Kettner C. The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets. Glycobiology. 2016 Sep; 26(9):907-910. PMID: 27654115.

    Read at: PubMed

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