Carlos J. Acuna-Villaorduna, MD

Adjunct Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Carlos Acuña-Villaorduña is an infectious disease specialist with interest in tuberculosis, tropical medicine, and mathematical modelling of infectious diseases. After finishing medical school, he worked as a researcher at the “Alexander Von Humboldt Tropical Medicine Institute” in Lima, Peru, the largest tropical medicine in South America, where he successfully collaborated in several research projects in tuberculosis epidemiology and diagnostics. After moving to the United States to complete his medical training, he earned a master degree in epidemiology at the “University of London”. He currently holds an appointment as Assistant Professor of Medicine at Boston University and provide care for patients at the tuberculosis clinic of Boston. Dr. Acuña-Villaorduña is interested in understanding the complex mechanisms leading to tuberculosis transmission in developing countries. His research focuses on investigating the ability of certain mycobacterial strains to survive in the environment and to produce infection and disease.

Publications

  • Published 9/18/2026

    Linde LR, Campbell JI, Horsburgh CR, Fox MP, Abubakar I, Acuna-Villaorduna C, Alikhan F, Andrade BB, Arriaga MB, Balcells ME, Becerra MC, Benjumea-Bedoya D, Bennet R, Blumenfeld A, Bonnet M, Brewer TF, Carvalho ACC, Caylà JA, Chakhaia T, Chan PC, Chaw L, Chen C, Del Corral H, Dobler CC, Fang CT, Faridi MMA, Faye A, Graham SM, Gupta RK, Hauri AM, Heinmueller P, Hesseling A, Hill PC, Huang LM, Huerga H, Jones-López EC, Kinikar A, Kirchner HL, Kritski A, Lecca L, Lee MR, Lee CH, Lee LN, Liu Q, Long R, MacPherson P, Mandalakas A, Marin D, Martinson N, Mave V, Mazahir R, Murray M, Nejat S, Pasqualini C, Ruan Q, Rubinstein F, Ruiz-Tagle C, van der Loeff MFS, Seddon JA, Shah L, Sharma S, Shen Y, Srivastava G, Stein C, Triasih R, Trieu L, Verhagen LM, Villalba JA, Wang JY, Yuen C, Zhang W, Golub J, Martinez L. Duration of effectiveness of tuberculosis preventive treatment across various tuberculosis burden settings: a systematic review and individual-participant meta-analysis. Lancet Respir Med. 2026 Sep 18. PMID: 42759526.

    Read at: PubMed

  • Published 8/12/2026

    Hamada Y, Surenthirarajah S, Gupta RK, Quartagno M, Acuna-Villaorduna C, Altet N, Diel R, Dominguez J, Floyd S, Gupta A, Jones-López EC, Lange C, van Leth F, Rueda IL, Mave V, Muñoz L, Paradkar M, Sester M, Prasad H, Shanaube K, Sharma SK, Sloot R, Sotgiu G, Vashishtha R, Abubakar I, Rangaka MX. Sex differences in tuberculosis incidence: a pooled analysis of 11 prospective cohort studies. EClinicalMedicine. 2026 Sep; 99:104146. PMID: 42802811.

    Read at: PubMed

  • Published 8/11/2026

    Campbell JI, Garing A, Lavache D, Quintero R, Bahad S, Goodwin S, Sinha P, Bouton TC, Acuna-Villaorduna C, Traber K, Canning M, Sabharwal V, Jacobson KR. Stigma among patients with TB infection in a low-TB-burden setting. IJTLD Open. 2026 Aug; 3(8):534-536. PMID: 42583503.

    Read at: PubMed

  • Published 7/27/2024

    Hamada Y, Quartagno M, Malik F, Ntshamane K, Tisler A, Gaikwad S, Acuna-Villaorduna C, Bhavani PK, Alisjahbana B, Ronacher K, Apriani L, Becerra M, Chu AL, Creswell J, Diaz G, Ferro BE, Galea JT, Grandjean L, Grewal HMS, Gupta A, Jones-López EC, Kleynhans L, Lecca L, MacPherson P, Murray M, Marín D, Restrepo BI, Shivakumar SVBY, Shu E, Sivakumaran D, Vo LNQ, Webb EL, Copas A, Abubakar I, Rangaka MX. Prevalence of non-communicable diseases among household contacts of people with tuberculosis: A systematic review and individual participant data meta-analysis. Trop Med Int Health. 2024 Sep; 29(9):768-780. PMID: 39073229.

    Read at: PubMed

  • Published 1/5/2023

    Hamada Y, Gupta RK, Quartagno M, Izzard A, Acuna-Villaorduna C, Altet N, Diel R, Dominguez J, Floyd S, Gupta A, Huerga H, Jones-López EC, Kinikar A, Lange C, van Leth F, Liu Q, Lu W, Lu P, Rueda IL, Martinez L, Mbandi SK, Muñoz L, Padilla ES, Paradkar M, Scriba T, Sester M, Shanaube K, Sharma SK, Sloot R, Sotgiu G, Thiruvengadam K, Vashishtha R, Abubakar I, Rangaka MX. Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis. EClinicalMedicine. 2023 Feb; 56:101815. PMID: 36636295.

    Read at: PubMed

Education

  • Universidad Peruana Cayetano Heredia, MD