Previous Trainee Seminars and Journal Clubs
| Spring 2024 VIM and ITP Trainee Seminar and Journal Club Series | |
| January 22 | STUDENT SEMINARS “Inflammasome Activation in HIV-1 Infection of Macrophages” Ivy Hughes, Gummuluru Lab and “Understanding the Role of BAFF Elevations and TACI Mutations in CVID” Erik Matson, Maglione Lab |
| January 29 | STUDENT SEMINARS “Investigating the Role of Oncostatin M in the Lungs especially during Pneumonia” Yewoo Lee, Traber Lab and “Investigating the Requirement of TCR Signaling to Activate T cell Populations” Christina McConney, Cappione Lab |
| February 5 | JOURNAL CLUB Badarinarayan, S.S. et al. HIV-1 Infection Activates Endogenous Retroviral Promoters Regulating Antiviral Gene Expression. Nucleic Acids Research 48(19):10890-10908, 2020. https://academic.oup.com/nar/article/48/19/10890/5918323 Presenter: Thomas Murphy |
| February 12 | JOURNAL CLUB Pasqual, G. et al. Monitoring T Cell-Dendritic Cell Interactions in vivo by Intercellular Enzymatic Labelling. Nature 553:496-500, 2018. https://www.nature.com/articles/nature25442 Presenter: Michael Vannini |
| February 19 | NO SEMINAR |
| February 26 | JOURNAL CLUB Yun, T. et al. Efficient Reverse Genetics Reveals Genetic Determinants of Budding and Fusogenic Differences between Nipah and Hendra Viruses and Enables Real-Time Monitoring of Viral Spread in Small Animal Models of Henipavirus Infection. J. Virol. 89(2):1242-1253, 2014 https://journals.asm.org/doi/10.1128/jvi.02583-14# Presenter: Jarod Herrera |
| March 4 | JOURNAL CLUB Pasqual, G. et al. TRIMα Restricts Poxviruses and is Antagonized by CypA and the Viral Protein C6. Nature 620:873-880, 2023 https://www.nature.com/articles/nature25442 Presenter: Joelle Johnson |
| Friday March 8 1:00 pm in L109AC |
DISSERTATION DEFENSE SEMINAR Callie Donahue |
| March 11 | JOURNAL CLUB McMyn, N.F. et al. The Latent Reservoir of Inducible, Infectious HIV-1 does not Decrease Despite Decades of Antiretroviral Therapy. J. Clin. Invest. 133(17):e171554, 2023. https://www.jci.org/articles/view/171554 Presenter: Julia Huynh |
| Thursday March 14 11:00 am in L112 |
DISSERTATION DEFENSE SEMINAR Victoria Kleiner |
| March 18 | JOURNAL CLUB Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles is Suppressed by Tetherin in a Species-Specific Manner. Cell Rep. 26(7):1841-1853.e6, 2019. https://www.sciencedirect.com/science/article/pii/S2211124719300944#sec4.4.12 Presenter: Elias Nafziger |
| March 25 | JOURNAL CLUB Suchanek, O. et al. Tissue-Resident B Cells Orchestrate Macrophage Polarisation and Function. Nat Commun.14:7081, 2023. https://www.nature.com/articles/s41467-023-42625-4 Presenter: Anna Tseng |
| Thursday March 28 1:00 pm in L112 |
DISSERTATION DEFENSE SEMINAR Josiane Fofana |
| April 1 | JOURNAL CLUB Man, S.M. et al. Inflammasome Activation Causes Dual Recruitment of NLRC4 and NLRP3 to the Same Macromolecular Complex. Proc. Natl. Acad. Sci. USA 111(20):7403-7408, 2014. https://www.pnas.org/doi/epdf/10.1073/pnas.1402911111 Presenter: Long Chu |
| April 8 | POSTDOCTORAL FELLOW SEMINAR Matthew Fish, PhD, Tomic Lab |
| April 15 | NO SEMINAR |
| April 22 | POSTDOCTORAL FELLOW SEMINAR Giulia Unali, PhD, Douam Lab |
| May 1 | TBA |
| Fall 2023 Microbiology and Immunology Trainee Seminar and Journal Club Series | |
| September 11 | STUDENT SEMINARS “Amidino-Rocaglates (ADRs) are Highly Selective Inhibitors of SARS-CoV-2 Infection Through Inhibition of Viral Protein Synthesis” Patrick Keiser, Davey Lab and “Unravelling Sex-Specific Mechanisms of Heterologous Immunity” Devin Kenney, Douam Lab |
| September 18 | DISSERTATION DEFENSE SEMINAR “Analysis of T Cell Subsets in Systemic Sclerosis Patients Reveals Altered Composition and Features of Dysfunction” Victoria Volfson-Sedletsky |
| September 25 | STUDENT SEMINARS “RNA Synthesis Termination Mechanisms by the Non-Segmented Negative Sense RNA Virus Polymerases” Victoria Kleiner, Fearns Lab and “Leveraging Marburg Virus Features to Identify Pan-Filovirus Functions of VP30” Ellen Suder, Mühlberger Lab |
| October 2 | STUDENT SEMINARS “Aim for the Legs! Ebola Virus Co-Opts the mRNA Decapping Complex Through the Scaffold Protein EDC4” Callie Donahue, Davey Lab and “Identifying Host Mechanisms of EBOV mRNA Regulation” Stephen Ross , Cifuentes and Mühlberger Labs |
| October 9 | NO SEMINAR |
| October 16 | STUDENT SEMINARS “Investigating Mechanisms of Ebola Virus Entry and Infection in Monocytes/Macrophages” Josiane Fofana, Gummuluru Lab and “OC43 Coronavirus Infection Induces Antigen-Specific Memory Boosted by CDG” Nathan Sanders, Mizgerd Lab |
| October 23 | STUDENT SEMINARS “Heterotypic T Cell Responses Against nsp12/nsp13 Associates with Lower Endemic Coronavirus Incidence” David Bean, Sagar Lab and “Accident Reconstruction: Investigating Immunological Intersections, Drivers of Inflammation, and Potential Exhaustion on the Roadways” Erika Smith-Mahoney, Cappione Lab |
| October 30 | STUDENT SEMINARS “Evaluating Perfluoroalkyl Substance-based Modulation of Host Susceptibility to Respiratory Viruses” Scott Adams, Douam Lab and “Identifying the Mechanism of IRF5 Activation in HIV-1 Infected Macrophages” Sita Ramaswamy, Gummuluru Lab |
| November 6 | STUDENT SEMINARS “Immune Detection of Defective HIV Provirus Transcriptional and Translational Products” Jonathan Kilroy, Henderson Lab and “Investigating the Role of Bacterial Polyphosphates in Legionella Infection of Murine Macrophages” Kara Vasilew, Bosmann Lab |
| November 13 | STUDENT SEMINARS “Investigating a Non-Coding RNA Regulating Flavivirus Infection” Elizabeth Chavez, Douam Lab and “Metabolic Inflammation in the Breast Tumor Microenvironment: Exploring the Impact of Type II Diabetes” Christina Ennis, Dries and Denis Labs |
| November 20 | NO SEMINAR |
| November 27 | NO SEMINAR |
| December 4 | STUDENT SEMINARS “Identification and Evaluation of Novel Lassa Virus Entry Inhibitors using Computational Counter Screening and Chemical Informatics” Brianna Close, Davey Lab and “The Anti-Inflammatory Effects of Opioid Receptor Antagonists During HIV-1 Infection” Chelsey Skeete, Gummuluru Lab |
| December 11 | STUDENT SEMINARS “Lung Interstitial Macrophage Response and Remodeling during Pneumonia” Elise Armstrong, Mizgerd Lab and “Exploring interactions between host DNA damage responses and early HIV-1 infection” Andrew Leal, Henderson Lab |
| December 18 | STUDENT SEMINARS “Assessing the Human Contraception Antibody’s Activity Against HIV” Sarah Dohadwala, Anderson Lab and “TBA” Joseph McWhirter, Sagar Lab |
| Spring 2023 Microbiology and Immunology Trainee Seminar and Journal Club Series | |
| January 23 | STUDENT SEMINARS “Elucidating the Role of Bacterial Polyphosphates in Legionella pneumophila Infection of Murine Macrophages” Kara Farquharson, Bosmann Lab and “Investigating the Impact of Opioid Signaling on HIV-Induced Innate Immune Activation in Microglia” Chelsey Skeete, Gummuluru Lab |
| January 30 | STUDENT SEMINARS “Development of a Topical Antibody-based Contraceptive: Determining Fc Functions in the Female Reproductive Tract” Emilie Mausser, Anderson Lab |
| February 6 | JOURNAL CLUB Zila V., et al. 2021. Cone-shaped HIV-1 Capsids are Transported Through Intact Nuclear Pores. Cell 184(4):1032-46. https://www.sciencedirect.com/science/article/pii/S0092867421000684?via%3Dihub Presenter: Ivy Hughes |
| February 13 | JOURNAL CLUB Lamichhane R., et al. 2019. TCR- or Cytokine-activated CD8+ Mucosal-associated Invariant T Cells are Rapid Polyfunctional Effectors that can Coordinate Immune Responses. Cell Reports 28(12):P3061-3076. https://www.cell.com/cell-reports/pdfExtended/S2211-1247(19)31102-7 Presenter: Christina McConney |
| February 20 | NO SEMINAR |
| February 27 | JOURNAL CLUB Yao Y., et al. 2018. Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and is Critical to Trained Immunity. Cell 175(6):1634-1650. https://www.sciencedirect.com/science/article/pii/S0092867418312546?via%3Dihub Presenter: Elise Armstrong |
| March 6 | JOURNAL CLUB Wang Q., et al. 2021. CARD8 is an Inflammasome Sensor for HIV_1 Protease Activity. Science 371(6535):eabe1707. https://www.science.org/doi/10.1126/science.abe1707 Presenter: Andrew Leal |
| March 13 | JOURNAL CLUB Minns D, et al. 2021. The Neutrophil Antimicrobial Peptide Cathelicidin Promotes TH17 Differentiation. Nat. Com. 12:1285 https://www.nature.com/articles/s41467-021-21533-5 Presenter: Yewoo Lee |
| March 20 | JOURNAL CLUB Abbott RK, et al. 2018. Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens. Immunity 48(1):133-146 https://www.sciencedirect.com/science/article/pii/S1074761317305241?via%3Dihub Presenter: Joseph McWhirter |
| March 27 | JOURNAL CLUB Stieh DJ, et al. 2016. TH17 Cells are Preferentially Infected very Early after Vaginal Transmission of SIV in Macaques. Cell Host & Microbe 19(4):5290540. https://www.sciencedirect.com/science/article/pii/S193131281630097X?via%3Dihub Presenter: Sarah Dohadwala |
| April 3 | STUDENT SEMINAR “iPCS-derived Organoid-based Model of Intestinal Filovirus Infection” Elizabeth Flores, Mühlberger & Mostoslavsky Labs |
| April 10 | POSTDOCTORAL FELLOW/RESEARCH SCIENTISTS “The Power of Mosquito Saliva in the Transmission of Arboviruses” Fabiana Feitosa-Suntheimer, Douam Lab |
| Thursday, April 13 |
DISSERTATION DEFENSE SEMINAR “Dynamics and Requirements for Protective Lung B Cell after Pneumococcal Infection” Neelou Etesami |
| April 17 | NO SEMINAR |
| June 5 | QUALIFYING EXAM SEMINARS “Antibody-Mediated Phagocytosis, Cellular Cytotoxicity and Physical Entrapment of Male Reproductive Tract Derived Pathogens in the Female Reproductive Tract” Sarah Dohadwala and “Defining the Licensing of TCR-Independent Human T Cell Activation” Christina McConney |
| Tuesday, June 6 |
QUALIFYING EXAM SEMINARS “Investigating Lung Interstitial Macrophage Remodeling during Bacterial Pneumonia” Elise Armstrong and “Defining the Roles of Vpr and DNA Damage Response Factors in HIV-1 Integration” Andrew Leal |
| Wednesday, June 7 |
QUALIFYING EXAM SEMINARS “Inflammasome Activation following HIV-1 and HIV-2 Infection” Ivy Hughes and “Oncostatin M: A Multifunctional Cytokine Upregulated during Pneumonia” Yewoo Lee and “Investigating the Humoral and T Cell Responses in HIV and TB Coinfection” Joseph McWhirter |
| Fall 2022 | |
| October 3 | STUDENT SEMINARS “Network mapping of an EBOV-host protein proximity screen reveals putative RNA processing complexes as important mediators of viral infection” Callie Donahue, Davey Labs and “Dual antiretroviral loaded nanoparticles for long-acting suppressive HIV therapy” Josiane Fofana, Gummuluru Lab |
| October 10 | NO SEMINAR Indigenous Peoples’ Day |
| October 17 | STUDENT SEMINARS “Prior SARS-CoV-2 infection, more than COVID-19 vaccination, associates with lower incidence of subsequent symptomatic endemic coronavirus infection” David Bean, Sagar Lab and KLHDC7B is a double-edged sword during coronavirus infection” Devin Kenney, Douam Lab |
| October 24 | STUDENT SEMINARS “Requirements for resident memory B cell establishment after pneumococcal infection” Neelou Etesami, Mizgerd Lab and “OC43 coronavirus infections in mice eliciting lunch resident memory” Nathan Sanders, Mizgerd Lab |
| October 31 | STUDENT SEMINARS “Uncovering viral RNA elements driving flavivirus escape from cell-intrinsic immunity” Elizabeth Chavez, Douam Lab and “Mechanistic insight into Diphyllin inhibition of Ebola virus infection” Patrick Keiser, Davey Lab |
| November 7 | STUDENT SEMINARS “Computational identification of novel small molecule viral entry inhibitors” Brianna Close, Davey Lab and “Transcriptional disease markers in survivor models of ebolavirus infection” Jacqueline Turcinovic, Connor Lab |
| November 14 | STUDENT SEMINARS “Transcriptomic analysis of the host response to Bundibugyo virus” Jamie Strampe, Connor Lab and “Characterizing the intrinsic properties of coronavirus discontinuous transcription” Stephen Ross, Cifuentes Lab |
| November 21 | STUDENT SEMINARS “Transcription of defective HIV proviruses trigger expression of innate immune response genes” Jonathan Kilroy, Henderson Lab and “Investigation of Marburg virus VP30 functions” Ellen Suder, Mühlberger Lab |
| November 28 | STUDENT SEMINARS “Investigating a novel miRNA-based mechanism regulating flavivirus infection” Scott Adams, Douam Lab and “IRF5 mediates persistent inflammatory response in HIV-1 infected macrophages” Sita Ramaswamy, Gummuluru Lab |
| Tuesday, November 29, 2:00 pm |
DISSERTATION DEFENSE SEMINAR “Extravascular B cell populations in the influenza A virus experienced lung” Michael Breen |
| December 5 | STUDENT SEMINARS “Determining the mechanism of action of a non-nucleoside inhibitor against the respiratory syncytial virus polymerase” Victoria Kleiner, Fearns Lab and “Investigating γδ T cells in HIV infection Erika Smith, Snyder-Cappione Lab |
| December 12 | STUDENT SEMINARS “Unraveling the spatial determinants of immunomodulation in the breast tumor microenvironment” Christina Ennis, Denis Lab and “The role of BAFF and its receptors in common variable immunodeficiency” Erik Matson, Maglione Lab |
| Spring 2022 | |
| January 24 | STUDENT SEMINARS “Investigating the Role of Heterotypic Immune Responses in the Protection Against Coronavirus Infections” David Bean, Sagar Lab and “Investigating the Role of Virus-Encoded Small RNAs in Ebola Virus Transcription Initiation” Stephen Ross, Cifuentes & Mühlberger Labs |
| January 31 | STUDENT SEMINARS “Uncovering Novel RNA Factors Involved in Permissiveness to Flavivirus Infection” Elizabeth Chavez, Douam Lab and “Structure-Activity Analysis of Natural Product Derivative Inhibitors of Ebola Virus Infection” Patrick Keiser, Davey Lab |
| February 7 | POSTDOC/RESEARCH SCIENTIST SEMINARS “Characterization of Ebola Virus Defective Genomes” Rebecca Johnson, Griffiths Lab and “Advancement of a Small Molecule Antiviral Therapeutic to Treat Poxvirus Infection” Scott Seitz, Connor Lab |
| February 14 | STUDENT SEMINARS “Harnessing Humanized Mouse Models to Identify Human Regulators of SARS-CoV-2 Infection” Devin Kenney, Douam Lab and “Remodeling of Lung Immunity After Endemic Coronavirus Infection” Nathan Sanders, Mizgerd Lab |
| February 21 | NO SEMINAR |
| February 28 | STUDENT SEMINARS “Investigation of Impact of Opioids of HIV Replication and Latency” Binita Basukala, Henderson Lab and “Malignant Cell Expression of the Aryl Hydrocarbon Receptor Induces PD-L1 and Immunosuppression in Models of Oral and Lung Cancer” Megan Snyder, Sherr Lab |
| March 7 | NO SEMINAR |
| Wednesday, March 9, 12:00 pm |
DISSERTATION DEFENSE SEMINAR “Novel Subsets of Resident Lymphocytes in Murine Lungs Recovered from Pneumococcal Pneumonia” Carolina Lyon De Ana |
| March 14 | JOURNAL CLUB Yukl, SA et al. (2020) Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103+ and Gut CD4+ T Cells. J. Virol. 95(2):e01331. https://journals.asm.org/doi/10.1128/JVI.01331-20 Presenter: Erika Smith |
| March 21 | JOURNAL CLUB Liu, X. et al. (2019) Human Cytomegalovirus Evades Antibody-mediated Immunity through Endoplasmic Reticulum-associated Degradation of the FcRn Receptor. Nat. Commun. 10:3020. https://www.nature.com/articles/s41467-019-10865-y.pdf Presenter: Scott Adams |
| Thursday, March 24 9:00 am |
DISSERTATION DEFENSE SEMINAR “Primate Lentiviral Viral Protein R and the DNA Damage Response: A Tale of Manipulation and Subversion” Sarah Nodder |
| Friday, March 25, 10:00 am |
DISSERTATION DEFENSE SEMINAR “Intragenic Elements Support the Transcription of Defective HIV-1 Proviruses” Jeffrey Kuniholm |
| March 28 | JOURNAL CLUB Ho, Y-C. et al. (2013) Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure. Cell 155(3):540. https://www.sciencedirect.com/science/article/pii/S0092867413011574?via%3Dihub Presenter: Jonathan Kilroy |
| Tuesday, March 29, 12:00 pm |
DISSERTATION DEFENSE SEMINAR “The Influence of the Lung Virome on the Pulmonary B Cell Repertoire” Fumiaki Aihara |
| April 4 | JOURNAL CLUB Reinert, L.S. et al. (2016) Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS. Nat. Commun. 7, 13348. https://www.nature.com/articles/ncomms13348.pdf Presenter: Chelsey Skeete |
| April 11 | JOURNAL CLUB Xu, W. et al. (2021) Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection. Immunity 54(3):5260541.e7. https://www.sciencedirect.com/science/article/pii/S1074761321000261?via%3Dihub Presenter: Kara Farquharson |
| April 18 | NO SEMINAR |
| April 25 | JOURNAL CLUB Perera, M.R. et al. (2022) A viral long non-coding RNA protects against cell death during human cytomegalovirus infection of CD14+ monocytes. Viruses 14(2):246. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874509/pdf/viruses-14-00246.pdf Presenter: Sita Ramaswamy |
| May 23 | DISSERTATION DEFENSE SEMINAR “Liver-dependent Lung Remodeling During Systemic Inflammation Alters Responses to Secondary Infection” Christine Odom |
| Wednesday, June 8, 12:00 pm |
QUALIFYING EXAM SEMINAR “The Impact of HIV Infection and Aging on the Diversity, Distribution, and Plasticity of ex vivo Effector Functions of Blood and Gut Mucosal Gamma Delta (γδ) T Cell Subsets” Erika Smith |
| June 13, 11:30 am |
QUALIFYING EXAM SEMINARS “IRF5 Mediated Persistent Inflammatory Response in HIV-1 Infected Macrophages” Sita Ramaswamy and “The Impact of Opioid Signaling on HIV-1 Induced Innate Immune Activation in Microglia” Chelsey Skeete |
| Wednesday, June 15, 11:30 am |
QUALIFYING EXAM SEMINARS “Elucidating t he Role of Polyphosphates on Legionella pneumophilia Infection of Murine Macrophages” Kara Farquharson and “Evaluating the Impact of 5′ Deficient HIV Proviruses on Chronic Inflammation” Jonathan Kilroy |
| Friday, June 24, 11:30 am |
QUALIFYING EXAM SEMINARS “Investigating a Novel mRNA-based Mechanism Regulating Flavivirus Infection” Scott Adams and “Defining and Inhibiting the Dependence of Lassa Virus Entry on Sialylation of Intracellular LAMP1” Brianna Close |
| Friday, July 22, 1:00 pm |
DISSERTATION DEFENSE SEMINAR “Flavivirus-Dependent Packaging of Aedes aegypti Saliva Proteins into Extracellular Vesicles Enhances Infection” Alexander Gold |
| Thursday, September 1, 12:00 pm |
DISSERTATION DEFENSE SEMINAR “Mycobacterium tuberculosis-driven Heterologous Immunity and Consequences in HIV-1 Co-infection” Bukola Adeoye |
| Fall 2021 | |
| September 20 | STUDENT SEMINARS “Investigating HIV-1-Specific B cell Responses in HIV-1 and Active Tuberculosis Co-Infection” Bukola Adeoye, Sagar Lab |
| September 27 | STUDENT SEMINARS “Intragenic Proviral Elements Support Transcription of Defective HIV-1 Proviruses” Jeffrey Kuniholm, Henderson Lab and “Heterogeneity of CD4 T Cells in Pneumococcal Pneumonia” Carolina Lyon De Ana, Mizgerd Lab |
| October 4 | STUDENT SEMINARS “Mosquito Protein ARGIL1 Enhances Human Cell Susceptibility to Flavivirus Infection” Alexander Gold, Colpitts and Douam Labs and “Liver-Dependent Lung Remodeling during Systemic Inflammation Shapes Responses to Secondary Infection” Christine Odom, Quinton Lab |
| October 11 | NO SEMINAR |
| October 18 | STUDENT SEMINARS “Network Analysis of Host Genome Screens Reveals Components of Autophagy that Mediate Ebola Virus Infection” Callie Donahue, Davey Lab |
| October 25 | STUDENT SEMINAR “Innate Immune Responses to HIV-1 Infection in Macrophages and Microglia” Sallieu Jalloh, Gummuluru Lab |
| November 1 | STUDENT SEMINARS “Lung B Cell Dynamics during Respiratory Infection” Neelou Etesami, Mizgerd Lab and “Differential Expression in Bundibugyo Ebolavirus Infected Macaques” Jamie Strampe, Connor Lab |
| Friday, Nov 5 11:00 am in Heibert Auditorium |
DISSERTATION DEFENSE SEMINAR “An Investigation of the Interconnections between Aging, Chronic Inflammation, and Anti-Viral Immunity” Rachel Yuen |
| November 8 | NO SEMINAR |
| November 15 | STUDENT SEMINARS “Potential Involvement of Cellular Protein PABP in nsNSV Transcription” Victoria Kleiner, Fearns Lab and “Test, Sequence, Trace: Using Genomics to Track Viral Spread at BU” Jacqueline Turcinovic, Connor Lab |
| Wednesday, Nov 17 9:00am in Heibert Auditorium |
DISSERTATION DEFENSE SEMINAR “IL-7-Dependent Regulation of Conventional and Regulatory T Cells in Type 1 Diabetes” Albert Jones |
| November 22 | STUDENT SEMINAR “Elucidating the Roles of VP30 and Cis-Acting Genomic Elements in Marburg Virus” Ellen Suder, Mühlberger Lab |
| November 29 | STUDENT SEMINARS “Profiling Transcription Factor and Cofactor Recruitment Utilizing a Novel Array-Based Approach” Heather Hook, Siggers Lab and “Trafficking and Other Fc Receptor-Mediated Functions of IgA in Human Vaginal Mucosa” Emilie Mausser, Anderson Lab |
| December 6 | “Dual Antiretroviral Loaded Nanoparticles for Long-Acting Suppressive HIV Therapy” Josiane Fofana, Gummuluru Lab and “T-bet Deficiency in Systemic Sclerosis and its Association with T Cell Exhaustion” Victoria Sedletsky, Dooms Lab |
| Spring 2021 | |
| January 25 | STUDENT SEMINARS (Remote only presentations) “Uncovering the Pro-viral Function of the Aedes aegypti Protein AAEL002675.” Alexander Gold, Douam Lab and “Innate Immune Response to SARS-CoV-2 in Macrophages” Sallieu Jalloh, Gummuluru Lab |
| February 1 | JOURNAL CLUB (Remote only presentation) Nelde, A. et al. SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition. Nature Immunology 22:74-85, 2021. https://pubmed.ncbi.nlm.nih.gov/32999467/ Presenter: David Bean |
| February 8 | NO SEMINAR |
| February 22 | JOURNAL CLUB (Remote only presentation) Leist, S.R., et al., A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice. Cell, 2020. 183(4): p. 1070-1085.e12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510428/ Presenter: Nathan Sanders |
| March 1 | JOURNAL CLUB (Remote only presentation) Wahl, Al, LE Gralinski, CE Johnson, et al. SARS-CoV-2 Infection is Effectively Treated and Prevented by EIDD-2801. Nature (2021) https://doi.org/10.1038/s41586-021-03312-w. Presenter: Devin Kenney |
| March 15 | STUDENT SEMINARS (Remote only presentations) “Potential involvement of cellular protein PABP in respiratory syncytial virus mRNA polyadenylation” Victoria Kleiner, Fearns Lab and “Immunological Consequences of Defective HIV Infection in Macrophages” Jeffrey Kuniholm, Henderson Lab |
| March 22 | STUDENT SEMINARS (Remote only presentations) “Investigation of Effects of Opioids on HIV Replication and Latency” Binita Basukala, Henderson Lab and “Biomarkers of Mortality in Lassa Fever” Jamie Strampe, Connor Lab |
| March 29 | POSTDOC/RESEARCH SCIENTIST SEMINARS (Remote only presentations) “Modeling SARS-CoV-2 Infection with Human Pluripotent Stem Cell-Derived Intestinal Organoids Reveals a Common Epithelial Inflammatory Response” Adam Hume, Mühlberger Lab and “No way to Escape: CD169 and Pathogenic Viruses” Judith Olejnik, Mühlberger Lab |
| Tuesday, March 30, at 11:00 am | DISSERTATION DEFENSE SEMINAR “Linoleic Acid-mediated Regulation of T Cell Cytokine-subset Composition in Type 1 Diabetes” Jaileene Hernandez Escalante |
| April 5 | JOURNAL CLUB (Remote only presentation) McCarthy, K.R. et al. Recurrent Deletions in the SARS-CoV-2 Spike Glycoprotein Drive Antibody Escape. Science 371(6534):1139-1142, 2021. https://science.sciencemag.org/content/371/6534/1139 Presenter: Brianna Close |
| April 12 | JOURNAL CLUB (Remote only presentation) Banadyga, L., et al. Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment is Associated with Glycoprotein Mutations within the Fusion Loop. mBio 12(1):e01438-20, 2021. https://mbio.asm.org/content/12/1/e01438-20.long Patrick Keiser, Davey Lab |
| April 26 | STUDENT SEMINARS (Remote only presentations) Josiane Fofana, Gummuluru Lab and “Functional Characterization of the Expanded PD-1+TIGIT+ CD4+ T Cell Population in Systemic Sclerosis” Victoria Volfson Sedletsky, Dooms Lab |
| Friday, April 30 @ 2:00 pm |
DISSERTATION DEFENSE SEMINAR “Induced Pluripotent Stem Cell Based Modeling of Gastrointestinal Disease using Human Intestinal Organoids” Aditya Mithal |
| July 28 | DISSERTATION DEFENSE SEMINAR “Investigating the Role of Antibody-Dependent Cellular Cytotoxicity in the Prevention of Mother-to-Child Transmission of HIV-1 Through Breastfeeding” Allison Thomas |
| Fall 2020 | |
| Tuesday, September 8, 1:00 PM |
DISSERTATION DEFENSE SEMINAR Eric Brownhill “Compromised Metabolic Function and Dysregulated Induction of Type 1 Interferon Promote Susceptibility in a Model for Tuberculosis Infection” |
| September 21 | STUDENT SEMINARS “Pluripotent Stem Cell Derived Organoid-Based Modeling of Intestinal SARS-CoV2 Infection” Aditya Mithal, Mostoslavsky Lab and “An ELISA Protocol with Resolution at High Sample Concentration Reveals Reactive Antibodies to SARS-CoV-2 in Unexposed Individuals” Rachel Yuen, Cappione Lab |
| Thursday, September 24, 11:00 AM |
DISSERTATION DEFENSE SEMINAR “The Establishment and Function of Lung Resident Memory B Cells after Bacterial Respiratory Infection” Kimberly Barker |
| September 28 | NO SEMINAR |
| October 5 | STUDENT QUALIFYING EXAM SEMINARS “Characterizing the Trafficking and Fusion of Ebola Virus in the Endolysosomal System” Callie Donahue and “Comparative Analysis of Cellular Stress Responses in Filovirus Infections” Ellen Suder |
| October 12 | NO SEMINAR |
| October 19 | NO SEMINAR |
| October 26 | STUDENT SEMINARS “Effects of Liver Activity on the Lung Immune Landscape” Christine Odom, Quinton Lab and “Antibody Dependent Cellular Cytotoxicity (ADCC) as a Correlate of Protection against Mother-to-Child Transmission of HIV-1” Allison Thomas, Sagar Lab |
| November 2 | STUDENT SEMINARS “Data Wrangling, Making Sense of Giant Data” Fumiaki Aihara, Kepler Lab and “Lung Resident Memory B Cell Dynamics in Response to Pneumococcal Infection” Neelou Etesami, Mizgerd Lab |
| November 9 | JOURNAL CLUB Li, X., et al. 2018. H5N1 influenza virus-specific miRNA-like small RNA increases cytokine production and mouse mortality via targeting poly(rC)-binding protein 2. Cell Research 28:157-171. Presenter: Stephen Ross |
| November 16 | STUDENT SEMINARS “Recombinant RSV Containing a Cre Recombinase: A Tool to Study Previous Infection” Michael Breen, Fearns Lab and “Determining the Role of IL-7 Signaling in Type I Diabetes” Albert Jones, Dooms Lab |
| November 23 | SENIOR RESEARCH SCIENTIST “Establishment and Characterization of a SARS-CoV-2 Infection Model of iPSC-Derived Alveolar Type 2 Cells” Adam Hume, Mühlberger Lab |
| November 30 | JOURNAL CLUB Schultz, P. et al. 2018. MicroRNA-122 Amplifies Hepatitis C Virus Translation by Shaping the Structure of the Internal Ribosomal Entry Site. Nat. Comm. 9:2613. Presenter: Elizabeth Chavez |
| December 7 | STUDENT SEMINARS – REMOTE ONLY “Investigating the Role of Active Tuberculosis Co-Infection on Plasma Breadth and Potency in Chronic HIV-1 Patients” Bukola Adeoye, Sagar Lab and “T-Cell Landscape of Heterotypic Immune Lungs” Carolina Lyon De Ana, Mizgerd Lab |
| December 14 | STUDENT SEMINARS “Development of a Sudan Virus Minigenome System to Study Nucleoprotein Mutations” Laura Avena, Griffiths Lab and “Characterizing the Sudan ebolavirus Variant Swarm during Serial Passage” Jacquelyn Turcinovic, Connor Lab |
| Spring 2020 | |
| January 27 | STUDENT SEMINARS “The Influence of The Lung Virome on Pulmonary B cells” Fumiaki Aihara, Kepler Lab and “Characterizing the Lung B Memory Cell Population After Respiratory Viral Infection” Michael Breen, Fearns Lab |
| February 3 | JOURNAL CLUB Callie Donahue, Davey Lab Martini, F., Arone, C., Hasset, A., Hall, W. W. & Sheehy, N. The ESCRT-0 Protein HRS Interacts with the Human T Cell Leukemia Virus Type 2 Antisense Protein APH-2 and Suppresses Viral Replication. J. Virol. 94, e01311-19, 2019. PMID: 31597781 |
| February 10 | QUALIFYING EXAM SEMINAR “Characterization of PD-1+TIGIT+ CD4+ T Conventional Cells in Systemic Sclerosis and Their Contribution to Fibrosis” Victoria Volfson Sedletsky, Dooms Lab |
| February 24 | JOURNAL CLUB Josiane Fofana, Gummuluru Lab |
| Thurs, Feb 27 @ 9:00 AM Location: TBA |
DISSERTATION DEFENSE SEMINAR “Discovery, Characterization, and Ligand Specificity Engineering of a Novel Bacterial Transcription Factor Inducible by Progesterone” R Cooper Baer |
| March 2 | STUDENT SEMINARS “Investigating the Role of Tuberculosis Disease on Humoral Immunity in Ugandans Living with HIV-1” Bukola Adeoye, Sagar Lab and “STAT3-Induced Liver Activity Remodels the Lung Landscape to Fortify Pulmonary Disease” Christine Odom, Quinton Lab |
| March 16 | ***C A N C E L E D*** |
| March 23 | MOVED TO MAY 4 |
| March 30 | JOURNAL CLUB Victoria Volfson Sedletsky, Dooms Lab Taylor, DK et al. T Follicular Helper-Like Cells Contribute to Skin Fibrosis. Sci. Transl. Med. 10(431):eaaf5307, 2018. PMID 29514998 |
| April 6 | STUDENT SEMINARS “The Function of Extracellular Vesicles and their Cargo during Dengue Virus Infection” Alexander Gold, Colpitts Lab and “Memory CD4+ T Cell Landscape after Lung Recovery from Pneumococcal Pneumonia” Carolina Lyon de Ana, Mizgerd Lab |
| April 13 | STUDENT/RESEARCH TECHNICIAN SEMINARS “Investigation of Effect of Chronic Opioid Misuse on HIV Pathogenesis and Latency Establishment” Binita Bashukala, Henderson Lab and “Distinct Roles of Gamma Delta T Cell Subsets in HIV and Aging-Associated Inflammation” Riley Pihl, Flow Core |
| April 27 | NO SEMINAR |
| May 4 | STUDENT SEMINARS “Mechanisms of HIV-1 RNA-Induced Activation of Microglia” Sallieu Jalloh, Gummuluru Lab and “Regulation of Autoreactive T Cell Fitness and Cytokine-Subset Distribution by n-6 Polyunsaturated Fatty Acids” Jaileene Hernandez Escalante, Dooms Lab |
| Tuesday, May 12 @ 12:00 pm |
DISSERTATION DEFENSE SEMINAR “Ebola Virus Induces a Type I Interferon Response in Induced Pluripotent Stem Cell-Derived Hepatocytes” Whitney Manhart |
| Thursday, June 25 @ 1:00 pm |
DISSERTATION DEFENSE SEMINAR “Cell-to-Cell Transmission and Intrinsic Mechanisms that Influence HIV Infection” Kyle Pedro |
| Fall 2019 | |
| Thurs, Sept 12 @ 1:00 PM in L110 |
DISSERTATION DEFENSE SEMINAR Alexander Barron “Perivascular Fibroblast Activation States in Human Skin Diseases” |
| September 23 | JOURNAL CLUB Carolina Lyon de Ana Vesely, M.C.A. et al. 2019. Effector TH17 Cells Give Rise to Long-Lived TRM Cells that are Essential for an Immediate Response Against Bacterial Infection. Cell 178:1176-1188. |
| September 30 | STUDENT SEMINARS Whitney Manhart, Mostoslavsky and Mühlberger Labs “Comparison of Human and Rousettus aegyptiacus Host Responses to Filovirus Infection” and Aditya Mithal, Mostoslavsky Lab “iPSC modeling of Tissue Resident Macrophage Function in Crohn’s Disease Pathogenesis” |
| October 7 | NO SEMINAR |
| October 21 | STUDENT SEMINARS Kimberly Barker, Mizgerd Lab “Resident Memory B Cells are an Important Component of Lung Adaptive Immunity” and Allison Thomas, Sagar Lab “A New Cell Line more Amenable to Access HIV-1 Antibody Dependent Cellular Cytotoxicity Against Broad Range of Variants” |
| October 28 | JOURNAL CLUB Victoria Kleiner Gilman, M.S.A. et al. 2019. Structure of the Respiratory Syncytial Virus Polymerase Complex. Cell 179:193-204. |
| November 4 | STUDENT SEMINARS Albert Jones, Dooms Lab “Determining the Role of IL-7 Signaling in Type 1 Diabetes” and Sarah Nodder, Gummuluru Lab “HIV-2 Vpr Suprpresses a Type III IFN Response in Monocyte-Derived Dendritic Cells” |
| Friday, Nov 15 @ 12:30 PM in L110 |
DISSERTATION DEFENSE SEMINAR Tessa Cressey “RNA Synthesis Initiation by the Nonsegmented Negative-Sense RNA Virus Polymerases” |
| November 18 | JOURNAL CLUB Ellen Suder Nikolic, J. et al. 2017. Negri Bodies are Viral Factories with Properties of Liquid Organelles. Nat. Comm. 8:58-70 |
| Friday, Nov 22 @ 12:00 PM |
DISSERTATION DEFENSE SEMINAR Molly Braun “Multifunctional Roles of the Respiratory Syncytial Virus Transcription and Genome Replication Machinery” |
| November 25 | STUDENT SEMINARS Eric Brownhill, Kramnik Lab “Dysregulation of Type 1 Interferon Compromises Metabolic Function and Promotes Susceptibility in an in vitro Model of Tuberculosis Infection” and Rachel Yuen, Wetzler Lab “TLR-Based Adjuvant Enhancement of the Germinal Center Reaction” |
| December 9 | POSTDOC/RESEARCH SCIENTIST Adam Hume, Mühlberger Lab “Ender’s Game: Finding Functional Lloviu Virus Genome Ends” and Rebecca Johnson, Griffiths Lab “Characterization of Ebola Virus Defective Genomes” |
| Spring 2019 | ||||
| February | 4 | Journal Club | Alexander Gold | Beerli, C., et al. 2018. Vaccinia virus hijacks EGFR signalling to enhance virus spread through rapid and directed infected cell motility. Nat. Microbiol. [Epub ahead of print]. |
| 11 | Student Seminars | Whitney Manhart (Mostoslavsky and Mühlberger Labs) and Aditya Mithal (Mostoslavsky Lab) |
“Development of an Ebola Virus Infection Model using iPSC-Derived Hepatocytes” and “iPSC Modeling of Tissue Resident Macrophage Function in Crohn’s Disease Pathogenesis” |
|
| 18 | No Seminar | |||
| 25 | Journal Club | Sallieu Jalloh | Daniels, B.P. et al. 2019. The nucleotide sensor ZBP1 and kinase RIPK3 induce the enzyme IRG1 to promote an antiviral metabolic state in neurons. Immunity 50:64-76. | |
| March | 4 | No Seminar | ||
| 11 | Journal Club | Christine Odom | Pillponsky, A.M. et al. 2019. Basophil-Derived tumor necrosis factor can enhance survival in a sepsis model in mice. Nat. Immunol. 20:129-140. | |
| 18 | Student Seminars | Michael Breen (Fearns Lab) and Allison Thomas (Sagar Lab) |
“Characterizing the Lung B Memory Cell Population after Respiratory Viral Infection” and “Investigating the Role of ADCC in the Prevention of Mother-To-Child Transmission of HIV-1” |
|
| Friday, Mar 22, 12 PM in L110 |
Dissertation Defense Seminar |
Matthew Gagne | “Cellular Mechanisms that Establish HIV-1 Latency in CD4+ T Cells and the Potential for their Manipulation as a Therapeutic Strategy” | |
| 25 | Journal Club | Laura Avena | Santiana, M. et al. 2018. Vesicle-Cloaked Virus Clusters are Optimal Units for Inter-organismal Viral Transmission. Cell Host Microbe 24(2):208-220. | |
| April | 1 | Journal Club | Bukola Adeoye | Castellano, P. et al. 2019. HIV Infection and Latency Induce a Unique Metabolic Signature in Human Macrophages. Sci. Rep. 9(1):3941-3954. |
| 8 | No Seminar | |||
| 15 | No Seminar | |||
| 22 | Student Seminars | Fumiaki Aihara (Kepler Lab) and Albert Jones (Dooms Lab) |
“The Influence of the Lung Virome on Pulmonary B Cells” and “Determining the Role of IL-7 Signaling in Type 1 Diabetes” |
|
| 29 | Journal Club | Neelou Etesami | Velazquez, E., et al. 2019. Endogenous Enterobacteriaceae Underlie Variation in Susceptibility to Salmonella Infection. Nat. Microbiol. [epub ahead of print]. | |
| June | 12 at 11:00 a.m. |
Qualifying Exam Seminars | Sallieu Jalloh and Alexander Gold |
“Elucidating the Mechanism and Consequences of HIV-1-Induced Innate Immune Activation in Microglia” and “The Role of Exosomes in Human to Mosquito Transmission of Dengue Viruses” |
| 14 at 11:00 a.m. |
Qualifying Exam Seminars | Neelou Etesami, Jeffrey Kuniholm, and Carolina Lyon de Ana |
“Characterization of Outer Membrane Vesicles and PorB1B as Novel Gonococcal Vaccine Candidates,”
“The Effects of TLR Ligand Vaccine Adjuvants on T Cell Memory” |
|
| July | 1 | Qualifying Exam Seminar | Christine Odom | “Hepatocyte STAT3-Dependent Mechanisms of Limiting Pneumonia Susceptibility During Sepsis” |
| 10 | Qualifying Exam Seminar | Bukola Adeoye | “Mycobacterium tuberculosis (MTB) Infection Impacts Human Immunodeficiency Virus-1 (HIV-1) Specific Humoral Responses in HIV-1/MTB Coinfection” | |
| Fall 2018 | ||||
| September | 17 | Student Seminars | Alexander Barron (Browning Lab) and Matthew Gagne (Henderson Lab) |
“T Cell Accumulation Accompanies Vascular Adventitial Fibroblast Specialization in the Inflamed Human Dermis” and “Strength of T Cell Signaling Regulates HIV-1 Replication and Establishment of Latency” |
| 24 | No Seminar | |||
| October | 1 | Student Seminar | R Baer (Galagan Lab) |
“Development of a Cell-Based Steroid Biosensor for Directed Evolution of a Bacterial Progesterone Sensitive Transcription Factor” |
| 8 | No Seminar | |||
| 15 | Journal Club | Jaileene Hernandez Escalante | Akondy, R.S., et al. 2017. Origin and Differentiation of Human Memory CD8 T Cells after Vaccination. Nature 552:362-367. | |
| 22 | Student Seminars | Tessa Cressey (Fearns and Mühlberger Labs) and Kyle Pedro (Henderson Lab) |
“Structural Determinants of the RSV Polymerase Involved in Coordinating the RNA Synthesis Initiation Complex” and “Investigating the Role of Novel HIV-2 Transcription Factors” |
|
| 29 | Journal Club | Fumiaki Aihara | Onder, L. et al. 2017. Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity 47:80-92. | |
| November | 5 | Student Seminars | Molly Braun (Fearns Lab) and Rachel Yuen (Wetzler Lab) |
“RNA Binding Properties and Localizations of the RSV Transcription Elongation Factor, M2-1” and “T Follicular Helper Cell and Germinal Center B Cell Responses Induced by TLR-Based Adjuvants” |
| 12 | No Seminar | |||
| 19 | Journal Club | Jeffrey Kuniholm | Zhang, Q. et al. 2018. Blockade of the Checkpoint Receptor TIGIT Prevents NK cell Exhaustion and Elicits Potent Anti-Tumor Immunity. Nat. Immunol. 19:723-732. | |
| 26 | Student Seminars | Kimberly Barker (Mizgerd Lab) and Sarah Nodder (Gummuluru Lab) |
“Pneumococcal Exposures Elicit Lung Plasma Cells and Memory B Cells Poised to Secrete Class-Switched Antibodies” and “Investigating the Role of HIV-2/SIVmac Vpr in Monocyte-Derived Dendritic Cells” |
|
| December | 3 | Journal Club | Aditya Mithal | De Schepper, S. et al. 2018. Self-Maintaining Gut Macrophages are Essential for Intestinal Homeostasis. Cell 175:400-415. |
| 10 | Student Seminars | Eric Brownhill (Kramnik Lab) and Jaileene Hernandez Escalante (Dooms Lab) |
“Interferon Immunopathology: Evaluating the Role of RNA-Dependent Protein Kinase (PKR) in Susceptibility to Tuberculosis” and “Regulatino of IL-10 Producing T cells by Polyunsaturated Fatty Acids” |
|
| Spring 2018 | ||||
| January | 29 | Microbiology Journal Club | Michael Breen | McCarthy, K.R. et al. 2018. Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses are Abundant in Adult Human Repertoires. Immunity 48(1):174-184. |
| February | 5 | Immunology Journal Club | Fumiaki Aihara | Grist, J.T. et al. 2018. Extracellular Lactate: A Novel Measure of T Cell Proliferation. J. Immunol. |
| 12 | No Seminar | |||
| Friday, Feb 16, 12:00 PM in X714 |
Dissertation Defense Seminar | Ludy Registre | “Examination of the Role of Envelope Directed Antibodies on Co-Receptor Usage in HIV-1B Infection” | |
| 19 | No Seminar | |||
| Tuesday, Feb 20, 1:00 PM |
Dissertation Defense Seminar | Michelle Fleury | “Expression and Function of Co-Inhibitory Receptors PD-1, TIGIT, TIM-3, and LAG-3 in Systemic Sclerosis” | |
| 26 | Student Seminars | Whitney Manhart (Mostoslavsky and Mühlberber Labs) and Rachel Yuen (Wetzler Lab) |
“Investigating a Virus that Doesn’t Exist: Generating a Minigenome System for Lloviu Virus” and “The Effect of Adjuvants on the Germinal Center Response and Development of Humoral Immunological Memory” |
|
| March | 5 | Microbiology Journal Club | Allison Thomas | Turner, D.L. et al. 2018. Biased Generation and In Situ Activation of Lung Tissue-Resident Memory CD4 T Cells in the Pathogenesis of Allergic Asthma. J. Immunol. 200(5):1561-1569. |
| 12 | Student Seminars | Eric Brownhill (Kramnik Lab) and Jaileene Hernandez Escalante (Dooms Lab) |
“Interferon Immunopathology: Evaluating the Drivers of Susceptibility to M. tuberculosis Infection” and “Investigating the Influence of Fatty Acids on T1D Autoreactive Prone T Cells” |
|
| 19 | No Seminar | |||
| 26 | Student Seminars | Kimberly Barker (Mizgerd Lab) and Sarah Nodder (Gummuluru Lab) |
“Investigating B Cell Contributions to Heterotypic Anti-Pneumococcal Immunity” and “Unintegrated HIV DNA: Dead End or Secret Reservoir?” |
|
| April | 2 | No Seminar | ||
| Tuesday, Apr 3, 10:00 AM |
Dissertation Defense Seminar | Ian Francis | “The Characterization of Novel Transgenic Murine Models of Neisseria Gonorrhoeae Infection and Development of a Natural Outer Membrane Vesicle Anti-Gonococcal Vaccine Candidate” | |
| Thursday, Apr 5, 11:00 AM |
Dissertation Defense Seminar | Stephanie Pavlovich | “Genomic Analysis and Examination of Innate Antiviral Immunity in the Egyptian Rousette Bat” | |
| 9 | Immunology Journal Club | Alexander Barron | Viera, S.M. et al. Translocation of a gut Pathobiont Drives Autoimmunity in Mice and Humans. Science 359(6380):1156-1161.
Accompanying Perspective Article |
|
| 16 | No Seminar | |||
| 23 | Postdoctoral Seminars | John Ruedas (Connor Lab) and Barbara Ludeke (Fearns Lab) |
“Change is Happening: Investigation of a Series of Growth-Adaptive Mutations Emerging in the Ebola Makona Glycoprotein” and “Building Blocks for a Non-Isotopic Assay for RSV RNA Polymerase Activity” |
|
| Wednesday, Apr 25, 2:00 PM |
Dissertation Defense Seminar | Sila Ataca | “Biophysical Characterization of Affinity Maturation in the Human Response to Anthrax Vaccine” | |
| 30 | ||||
| May | 14 | Qualifying Exam Seminars | Albert Jones and Aditya Mithal, and Allison Thomas |
“Impacts of IL-7 Signaling Inhibition on Type 1 Diabetes” and “Defective Macrophages- Investigating a New Paradigm of Crohn’s Disease Pathogenesis” and “Investigating the Role of Antibodies Capable of Mediating Cellular Cytotoxicity in Mother-to-Child-Transmission of HIV-1” |
| Tuesday, May 15, 12:00 PM in L112 |
Qualifying Exam Seminars | Fumiaki Aihara and Michael Breen |
“The Influence of the Lung Virome on Pulmonary B Cells” and “Characterizing the Lung B Memory Cell Population after Respiratory Viral Infection” |
|
| Fall 2017 | ||||
| September | 25 | Microbiology Journal Club | Matthew Gagne | Foster TL, et al. 2016. Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction. Cell Host Microbe. 20(4):429-442. |
| October | 2 | Student Seminars | Alexander Barron (Browning Lab) and Matthew Gagne (Henderson Lab) |
“VCAM Expression by Vascular Adventitial Fibroblasts Correlates with Perivasicular T Cell Accummulation in Human Skin Diseases” and “The Effects of Differential T Cell Signaling on HIV Transcription and Latency” |
| 9 | No Seminar | |||
| 16 | Immunology Journal Club | Whitney Manhart | Jaitin DA, et al. 2016. Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq. Cell 167(7):1883-1869. | |
| 23 | No Seminar | |||
| 30 | Inflammation Journal Club | Molly Braun | Takata, MA et al. 2017. CG Dinucleotide Suprpression Enables Antiviral Defence Targeting non-self RNA. Nature 550(7674):124-127. | |
| November | 6 | Student Seminars | Tessa Cressey (Fearns/Muhlberger Labs) and Kyle Pedro (Henderson Lab) |
“Initiation Mechanisms of the RSV Polymerase” and “The Contribution of DC-Mediated and T Cell Receptor Signaling to HIV trans-infection” |
| 13 | Microbiology Journal Club | Albert Jones | Naik, S et al. 2017. Inflammatory Memory Sensitizes Skin Epithelial Stem Cells to Tissue Damage. Nature 26:550(7677):475-480. | |
| 20 | Postdoctoral Seminars | Leena Panneerseelan-Bharath (Microbiology) and Antoine Guillon (Pulmonary) |
“Metformin Treatment for Aging-Induced Immune Cell Dysfunction” and “Are Tissue-Resident Lung Macrophages Remodeled or Reprogrammed by Heterotopic Immunity?” |
|
| 27 | Immunology Journal Club | Gregory Hall | Rosshart, SP et al. Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance. Cell , Volume 171 , Issue 5 , 1015 – 1028.e13. | |
| December | 4 | Student Seminars | R Baer (Galagan Lab) and Molly Braun (Fearns Lab) |
“Discovery and Characterization of a Novel Progesterone Sensitive Bacterial Transcription Factor” and “Factors Affecting RNA Elongation by the RSV Polymerase” |
| 11 | Inflammation Journal Club | Eric Brownhill | Lachmandas E et al. Microbial Stimulation of Different Toll-like Receptor Signalling Pathways Induces Diverse Metabolic Programmes in Human Monocytes. Nat. Microbiol. 2:16246. | |
| Spring 2017 | ||||
| January | 9 | Microbiology Journal Club | Sila Ataca | Briney, B. et al. 2016. Tailored Immunogens Direct Affinity Maturation Toward HIV Neutralizing Antibodies. Cell 166:1459-1470. |
| 16 | No Seminar | |||
| 23 | Immunology Journal Club | Kyle Pedro | Park, R.J. et al. 2016. A Genome-Wide CRISPR Screen Identifies a Restricted set of HIV Host Dependency Factors. Nat. Genetics [Epub ahead of print]. | |
| 30 | Inflammation Journal Club | Christina Lisk | Hutton, A.J. et al. 2017. Human Lung Fibroblasts Present Bacterial Antigens to Autologous Lung Th Cells. J. Immunol. 198:110-118. | |
| February | 6 | Postdoctoral Fellow Seminars | John Ruedas (Connor Lab) and Sarah Shearer (Fearns Lab) |
“Common Occurrence of Tissue-Culture Adapted Ebola Viruses Caused by a Single Mutation in the Glycoprotein Fusion Loop” and “Initiation of Respiratory Syncytial Virus Transcription and Replication” |
| 13 | Student Seminars | Molly Braun (Fearns Lab) and Matthew Gagne (Henderson Lab) |
“The Multifunctional Role of a Domain in the RSV Polymerase” and “The Effects of Differential T Cell Stimulation on HIV Infection and Reactivation” |
|
| 20 | No Seminar | |||
| 27 | Microbiology Journal Club | Rachel Yuen | Deriu, E. et al. 2016. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS Pathogens 12(5): e1005572. | |
| March | 6 | Immunology Journal Club | Matthew Gagne | Druzd, D. et al. 2017. Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses. Immunity 46:120-132. |
| 13 | Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar | |||
| 20 | Postdoctoral Fellow Seminar | Dequina Nicholas (Nikolajczyk Lab) and Judith Olejnik (Mühlberger Lab) |
“Fatty Acid Uptake Unexpectedly Supports a Th17 Cytokine Signature in Type 2 Diabetes (T2D) Inflammation” and “Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Response in Human Macrophages” |
|
| 27 | Student Seminars | Tessa Cressey (Fearns and Muhlberger Labs) and Ludy Registre (Sagar Lab) |
“Relating Polymerase Structure to Initiation of RNA Synthesis” and “CXCR4 Variants are Neutralization Resistant Compared to CCR5-Using Viruses in HIV-1B” |
|
| April | 3 | Microbiology Journal Club | Kimberley Barker | Zipperer, A. et al. 2016. Human Commensals Producing a Novel Antibiotic Impair Pathogen Colonization. Nature 353:511-529. |
| 10 | Immunology Journal Club | Ian Francis | Gury-BenAri, M., et al. 2016. The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome. Cell 166(5):1231-1246. | |
| 17 | No Seminar | |||
| 24 | Student Seminars | R Baer (Galagan Lab) and Kyle Pedro (Henderson Lab) |
“Discovery and Characterization of a Novel Steroid-Sensing Transcription Factor from a Bacterium” and “The Contribution of DC-Mediated and T Cell Receptor Signaling to HIV trans-infection” |
|
| May | 1 | Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar | ||
| 8 | Postdoctoral Fellow Seminars | Luis Agosto (Henderson Lab) and Michael Reiser (Wetzler Lab) |
“HIV Latency after Cell-to-Cell Transmission to Restin gCD4+ T Cells” and “The TLR Ligand Based Adjuvant, Neisserial Porin PorB, and its Mechanism of Adjuvant Activity” |
|
| Monday May 22 @ 10:00 a.m. |
Dissertation Defense Seminar | Kaitlin Sawatzki | “Examination of the Immunoglobulin Repertoire Before and After Anthrax Vaccine Adsorbed Immunization” | |
| Tuesday May 23 @ 10:00 a.m. |
Qualifying Exam Seminars | Jaileene Hernandez-Escalante and Rachel Yuen |
“Investigating the Lipid Metabolic Dysregulation of T1D Autoreactive T Cells” and “Investigating the Role of Adjuvants in the Development of Humoral Immunological Memory” |
|
| Thursday May 25 @ 1:00 p.m. | Qualifying Exam Seminars | Eric Brownhill and Whitney Manhart |
“Macrophages in TB: A Study in Stress Management” and “Development of an Ebola Virus Pathogenesis Model using iPSC-Derived Hepatocytes” |
|
| Thursday June 1 @ 10:00 a.m. | Qualifying Exam Seminar | Sarah Nodder | “Investigating Vpr-Mediated DNA Damage Responses during HIV Infection” | |
| Thursday June 22 @ 12:00 p.m. | Qualifying Exam Seminar | Kimberly Barker | “Investigating B Cell Contributions to Naturally-Acquired Heterotypic Immunity to Pneumococcus” | |
| Fall 2016 | ||||
| September | 26 at 11:30 AM |
Microbiology Student Qualifying Exam Seminar | Alexander Barron (Browning Lab) |
“Regulation of Inflammation-Stimulated Protein Transport in Dermal Fibroblasts by Doublecortin-Like Kinase 1” |
| October | 3 | Microbiology Journal Club | Whitney Manhart | Chuong, E.B. et al. 2016. Regulatory Evolution of Innate Immunity Through Co-Option of Endogenous Retroviruses. Science 351:1083-1087. |
| 10 | No Seminar | |||
| 17 | Student Seminars | Michelle Fleury (Dooms Lab) and Ian Francis (Wetzler Lab) |
“Characterizing Immune Dysfunction in Systemic Sclerosis” and “Host Response to Neisseria gonorrhoeae Infection in Female Wild Type Mice is Dictated by the Dominant Sex Hormone” |
|
| 24 | Inflammation Journal Club | Cari Meisel | Li, W.A. et al. 2016. The Effect of Surface Modification of Mesoporous Silica Micro-Rod Scaffold on Immune Cell Activation and Infiltration. Biomaterials 83:249-256. | |
| 31 | Immunology Journal Club | Emad Arafa | Xiong, H. et al. 2016. Innate Lymphocyte/Ly6Chi Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance. Cell 165:679-689. | |
| November | 7 | Student Seminars | Sila Ataca (Kepler Lab) and Stephanie D’Souza (Kepler Lab) |
“Biophysical Characterization of Immunoglobulins during Affinity Maturation in the Human Response to Anthrax Vaccine” and “Immunogenomics of the Egyptian Fruit Bat, an Important Viral Reservoir” |
| 14 | Microbiology Journal Club | Sarah Nodder | Muenchhoff, M et al. 2016. Nonprogressing HIV-infected Children Share Fundamental Immunological Features of Nonpathogenic SIV Infection. Sci Transl Med 8:358ra125.Supplementary Materials. | |
| 21 | Postdoctoral Seminar | Michelle Olsen (Connor Lab) and Kristen Peters (Connor Lab) |
“Mechanisms of Ebolavirus Dependence on Polyamines and Hypusinated-eIF5A” and “Early Term Placental Explants as an ex vivo Model of Zika Virus Infection” |
|
| 28 | Inflammation Journal Club | Jaileene Hernandez | Bengsch, B. et al. 2016. Bioenergetic Insufficiencies due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 are an Early Driver of CD8+ T Cell Exhaustion. Immunity 45:1-16. | |
| December | 5 | Sr. Research Scientist |
Hisashi Akiyama | “Role of Myeloid Cells in HIV-1 Pathogenesis” |
| 12 | Immunology Journal Club | Gregory Hall | Meyer zu Horste, G. et al. 2016. RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression. Cell Reports 16:392-404. | |
| Spring 2016 | ||||
| February | 1 | Microbiology Journal Club | Tessa Cressey | Long, J.S. et al. 2016. Species difference in ANP32A underlies influenza A virus polymerase host restriction. Nature, 529(7584), 101–104. |
| 8 | No Seminar | |||
| Friday, Feb 12 @ 12:00 PM | DISSERTATION DEFENSE SEMINAR | Krishna Moody | “Attenuation of BCR-TLR Responses by FcγRIIB” | |
| 15 | No Seminar | |||
| 22 | Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar | |||
| 29 | Student Seminars | Michelle Fleury and Ludy Registre |
“Role of Immunoregulatory Pathways in Systemic Sclerosis” and “Neutralization Differences Between CCR5 and CXCR4 Tropic Viruses in HIV-1B Infection” |
|
| March | Friday, Mar 4 @ 12:00 PM | DISSERTATION DEFENSE SEMINAR | Emily Nelson | “Examination of the Cellular Stress Response and Post-transcriptional Regulation of RNA during Ebola Virus Infection” |
| 7 | Inflammation Journal Club | Christina Lisk | Weisel, F.J. et al. 2016. A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells. Immunity 44: 116-130. | |
| 14 | No Seminar | |||
| 21 | Immunology Journal Club | Barry Horne | Lood, C., et al. 2015. Neutrophil Extracellular Traps Enriched in Oxidized Mitochondrial DNA are Interferogenic and Contribute to Lupus-like Disease. Nat. Med. 22:146-153. | |
| Friday, Mar 25 @ 11:00 AM | DISSERTATION DEFENSE SEMINAR | Gregory Wasserman | “A Discrete Population of Ciliated Cells Express the piRNA Binding Protein MIWI2 to Regulate Lung Inflammation” | |
| 28 | Student Seminars | Matthew Gagne and Grace Olinger |
“Effects of Differential T Cell-associated Signals on HIV Infection” and “Investigating the Duplication Within the Attachment Glycoprotein Gene of Human Respiratory Syncytial Virus (HRSV)” |
|
| April | 4 | Microbiology Journal Club | R Baer | Westerman, A.J. et al. 2016. Dual RNA-seq Unveils Noncoding RNA Functions in Host-pathogen Interactions. Nature 529:496-501. |
| 11 | No Seminar | |||
| 18 | No Seminar | |||
| 25 | No Seminar | |||
| May | 2 | Inflammation Journal Club | Margaret Baker | Almeida et al. 2015. The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease. Immunity 43:264-276. |
| Thursday, May 5 @ 1:00 PM | DISSERTATION DEFENSE SEMINAR | Munir Mosaheb | “Immunological Responses and Mechanisms of Action of the TLR2-ligand Neisserial PorB Vaccine Adjuvant” | |
| 9 | Immunology Journal Club | Matthew Gagne | Wang, Z. et al. 2016. CRISPR/Cas9-derived Mutations both Inhibit HIV-1 Replication and Accelerate Viral Escape. Cell Reports 15:481-489. | |
| June | Wednesday, June 1 @ 12:00 PM |
Qualifying Exam Seminars | Kyle Pedro | “The Impact of Signaling from the Infectious Synapse on HIV-1 Infection and the Establishment of Latency” |
| 6 | Qualifying Exam Seminars | R Baer and Molly Braun and Tessa Cressey |
“Characterization and Directed Evolution of Hormone Sensitive Bacterial Transcription Factors for use in Biosensing Applications” and “Factors Affecting Viral Transcription during Respiratory Syncytial Virus Infection” and “Investigating Filovirus Replication and Transcription Mechanisms” |
|
| 13 | Trainee Travel Award Seminars | Matthew Gagne and Kaitlin Sawatzki |
Cold Spring Harbor Meeting on Retrovirus and Gordon Conference on Antibody Biology and Engineering |
|
| Fall 2015 | ||||
| September NOTE: Seminar is 12:00-1:30 pm |
21 | Microbiology Student Qualifying Exam Seminars | Sila Ataca | “Biophysical Characterization of Immunoglobulins during Affinity Maturation in the Human Response to Anthrax Vaccine” |
| Stephanie D’Souza | “Immunogenomics of the Egyptian Fruit Bat, an Important Viral Reservoir” | |||
| Ian Francis | “Evaluation of Neisseria gonorrhoeae outer Membrane Vesicles as a Vaccine Candidate for Gonococcal Infection using a Novel Transgenic Mouse Model” | |||
| 28 | Immunology Journal Club | Caitlin Miller | Grow E.J. et al. Intrinsic Retroviral Reactivation in Human Preimplantation Embryos and Pluripotent Cells. Nature 522(7555):221-225, 2015. | |
| Tuesday 29 @ 11:00 AM |
DISSERTATION DEFENSE | Fadie Coleman | “Influence of Macrophage NF-kB Activation on Pneumococcal Pneumonia” | |
| October | 5 | Microbiology Journal Club | Molly Braun | Leung, D.W. et al. An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions. Cell Reports 11(3):376-389, 2015. |
| 11 | No Seminar | |||
| 19 | Research Scientist Seminar | Hisashi Akiyama | “Role of CD169/Siglec-1 in HIV-1 Dissemination and Evasion from Antiviral Immune Responses” | |
| 26 | No Seminar | |||
| November | 2 | Inflammation Journal Club | George Papadopoulos | Warnatsch, A. et al. Neutrophil Extracellular Traps License Macrophages for Cytokine Production in Atherosclerosis. Science 349:316-320, 2015. |
| 9 | Immunology Journal Club | Alexander Barron | Brunham, R.D. A Chlamydia Vaccine on the Horizon. Science 348:1322-1323, 2015.Stary, G. et al. Vaccines. A Mucosal Vaccine Against Chlamydia trachomatis Generates two Waves of Protective Memory T Cells. Science 348:aaa8205 | |
| 16 | Student Seminars | Kaitlin Sawatzki and Gregory Wasserman |
“Non-Specific Activation of Autoreactive B Cells after Anthrax Vaccination Delays Protection” and “Miwi2 Exerts piRNA Independent Regulation of Innate Immunity during Bacterial Pneumonia” |
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| 23 | Research Scientist Seminar | Adam Hume | “Marburg Virus VP35 Function in Human and Bat Cells” | |
| 30 | Inflammation Journal Club | Christina Lisk | Gaudet, R.G. et al. Cytosolic Detection of the Bacterial Metabolite HBP Activates TIFA-Dependent Innate Immunity. Science 348:1251-1256, 2015. | |
| December | 7 | No Seminar | ||
| 14 | No Seminar | |||
| Spring 2015 | ||||
| January | 26 | Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar | ||
| February | 9 | Immunology Journal Club | Cancelled – Snow | |
| 16 | No Seminar | |||
| 23 | Microbiology Journal Club | Grace Olinger | Hotard, A.L. et al. 2015. Identification of Residues in the Human Respiratory Syncytial Virus Fusion Protein that Modulates Fusion Activity and Pathogenesis. J. Virol. 89:512-522 | |
| March | 2 | Microbiology Journal Club | Matthew Gagne | Gardner, M.R. et al. 2015. AAV-Expressed eCD4-Ig Provides Durable Protection from Multiple SHIV Challenges. Nature [Epub ahead of print]. |
| 9 | Student Seminar | Kaitlin Sawatzki (Kepler Lab) |
“An Assessment of Immunoglobulin Repertoire Sequencing: Getting Real with Big Data” | |
| 16 | Immunology Journal Club | Raquel Rodriguez | Nice, T.J. et al. 2015. Interferon-gamma Cures Persistent Murine Norovirus Infection in the Absence of Adaptive Immunity. Science 347:269-73. | |
| 23 | Postdoctoral Seminar | Anna Belkina (Snyder-Cappione Lab) |
“New Insights into Immune Exhaustion Using 16-Color Flow Cytometry” | |
| 30 | Microbiology Journal Club | Stephanie D’Souza | Selinger, C. et al. 2014. Cytokine Systems Approach Demonstrates Differences in Innate and Pro-Inflammatory host Responses Between Genetically Distinct MERS-CoV Isolates. BMC Genomics 15:1161-1176. | |
| April | 6 | Student Seminars | Michelle Fleury (Dooms Lab) and Ludy Registre (Sagar Lab) |
“Role of Immune Cell Dysfunction in Scleroderma Pathogenesis” and “The Role of Anti-V3 Loop Neutralizing Antibodies on the Emergence of CXCR4 Tropism in HIV-1B” |
| 13 | Microbiology Journal Club | Kaitlin Sawatzki | McHeyzer-Williams, L.J. et al. 2015. Class-Switched Memory B cells Remodel BCRs within Secondary Germinal Centers. Nat. Immunol. 16:296-307. | |
| 20 | No Seminar | |||
| 27 | Postdoctoral Seminar | Tathagat Ray (Ingalls Lab) |
“Cross Talk Between Complement System and Toll-like Receptors: Implication in Inflammation and Immunity” | |
| May | 4 | Immunology Journal Club | Alicia Wooten | Li, D. et al. 2014. IL-33 Promotes ST2-Dependent Lung Fibrosis by the Induction of Alternatively Activated Macrophages and Innate Lymphoid Cells in Mice. J. Allergy Clin. Immunol. 134:1422-1432 |
| 11 | Postdoctoral Seminar | Luis Agosto (Henderson Lab) |
“HIV Replication in Macrophages during P. gingivalis Co-Infection” | |
| 13 | DISSERTATION DEFENSE | Kristie Hilliard | “The Functional Significance of the Lung-Liver Axis During Pneumonia” | |
| 27 | Qualifying Exam Seminars | Matthew Gagne and Grace Olinger and Sila Ataca |
“Interrogating the Effects of Differential Signaling on HIV Transcription using a Tunable System” and “Investigating the Effects of Duplications within the Attachment Glycoprotein Gene of Clinically Isolated Human Respiratory Syncytial Virus (HRSV) Strains” and “Characterization of Antibodies during Affinity Maturation in the Human Response to Anthrax Vaccine” |
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| July | 16 10:00 AM | DISSERTATION DEFENSE | Suzanne Kijewski | “Mechanistic Differences in Interactions of HIV-1 and HIV-2 with Dendritic Cells” |