• Ongoing studies

Health Outreach Program for the Elderly (HOPE)

The Health Outreach Program for the Elderly (HOPE) study, funded by the National Institute on Aging (NIA), is a long-term study of memory and aging. HOPE is a community-based resource that is intended for people with and without memory concerns. Participants will complete annual visits to assess their memory and other thinking skills. Following their visit, participants will receive feedback about their results and will have the opportunity to speak with a clinician. HOPE allows participants to play a more active role in their own healthcare. This study aims to collect a longitudinal set of data on a large, diverse group to advance our knowledge on the diagnosis, prevention and treatment of Alzheimer’s disease and related disorders. We are also recruiting participants with a history of contact sports to help us understand how repetitive head impacts affect a person’s risk of developing later-life neurologic disorders. Locations in Boston and Needham

You may be eligible to participate if you:

  • Are 65 years of age or older without memory concerns or
  • Are 50 years or older with memory concerns
  • Have a caregiver or study partner who can accompany you to your annual study visit


  • Public Data Sets

At the CBI much of our research on Alzheimer’s Disease is done using two publicly available research data sets, which we are also involved in contributing to.




  • Ongoing trials

We are involved in several studies coordinated by Boston University’s Alzheimer’s Disease Center

Alzheimers Disease NeuroImaging Initiative (ADNI)

Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4 Study)



  • Finished trials