New Publication – Contextualized Protein-Protein Interactions
Source: Patterns Highlights We present PPI Context: contextualization of existing literature-curated PPIs A resource for filtering PPIs by cell-line information mined from reporting studies A fast and flexible pipeline implementing the presented data mining method The Bigger Picture Existing literature-curated protein-protein interaction (PPI) databases usually aggregate cell-type-agnostic interactions, yet PPIs are dependent on environmental conditions. […]
Evans Days of Research – Dr. Vijaya Kolachalama Receives Outstanding Research Collaborator Award
Vijaya B. Kolachalama, PhD, FAHA, Assistant Professor of Medicine in the Section of Computational Biomedicine was awarded an Outstanding Research Collaborator Award as part of the Annual Department of Medicine Evans Days. Dr. Kolachalama’s research interests include phenotyping neurodegeneration, digital pathology, as well as musculoskeletal and cardiovascular diseases, with a specific focus on machine learning. […]
Dr. Joshua Campbell Receives Shipley Prostate Cancer Pilot Grant Award
Source: BU School of Medicine Dr. Joshua Campbell, Assistant Professor Medicine/Computational Biomedicine, received a Shipley Prostate Cancer Pilot Grant Award. Please see below for more information on Dr. Campbell’s joint project with Drs. Gerald Denis and Andrew Emili: Protein-protein interactions (PPIs), which constitute an essential step in cell biology that, when disrupted, can cause profound […]
Bioinformatics Analyst – Darren Chiu
Darren Chiu, of the Mazzilli Lab, recently transitioned from Research Technician to Bioinformatics Analyst. Before joining the lab, Darren completed his master’s degree in Immunology at Harvard University, where his research focused on discovering non-coding functional single nucleotide polymorphisms (SNPs) associated with autoimmune diseases and investigating the regulatory mechanism of each SNP on gene expression. […]
New Hire – Jing Yu
Jing Yu recently joined the Section as a Research Study Assistant, working with Dr. Jennifer Beane and Dr. Vijaya Kolachalama. Jing graduated from Boston University in May of 2020, with a degree in Computer Science and Mathematics. Currently she is working on projects pertaining to deep learning approaches to semantic segmentation of the epithelial regions […]
Largest-Ever Study of Prostate Cancer Genomics in Black Patients IDs Potential Targets for Precision Therapies
Source: BU School of Medicine Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities. Now, in the largest study of its kind to date, researchers from BUSM, UC San Francisco […]
BU Scientists Awarded $1.9 Million to Accelerate Coronavirus Research
Source: The Brink Since the novel and fast-spreading SARS-CoV-2 coronavirus first upended life in the United States and around the world, scientists at Boston University’s National Emerging Infectious Diseases Laboratories (NEIDL) have dropped nearly every other research project to focus on understanding and combating the virus. Now, BU scientists have received nearly $1.9 million in […]
Deep Learning Algorithm Outperforms Experts in Making Alzheimer’s Diagnosis
Source: The Brink Alzheimer’s disease is the sixth leading cause of death in the United States. Today, more than five million Americans are living with the neurodegenerative disorder, and that number is predicted to rise to 14 million by 2050. Yet, because different people have different symptoms, it can be hard to get a clear […]
AI Algorithm Can Accurately Predict Risk, Diagnose Alzheimer’s Disease
Source: BU School of Medicine Researchers have developed a computer algorithm based on Artificial Intelligence (AI) that can accurately predict the risk for and diagnose Alzheimer’s disease using a combination of brain magnetic resonance imaging (MRI), testing to measure cognitive impairment, along with data on age and gender. The AI strategy, based on a deep […]
Boston University Investigators and Staff Attend 2020 Stand Up to Cancer Scientific Summit
Investigators and staff from BU recently attended the 2020 Stand up to Cancer Scientific Summit on behalf of our SU2C-LUNGevity-ALA-AACR Lung Cancer Interception Dream Team. Dr. Avi Spira (principal investigator), Dr. Sarah Mazzilli (junior investigator) and Dr. Liz Moses (project manager), as well as collaborators from UCLA, co-lead Dr. Steve Dubinett and Roswell Park Cancer […]