Largest-Ever Study of Prostate Cancer Genomics in Black Patients IDs Potential Targets for Precision Therapies
Source: BU School of Medicine
Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.
Now, in the largest study of its kind to date, researchers from BUSM, UC San Francisco (UCSF), and Northwestern University have identified genes that are more frequently altered in prostate tumors from men with African ancestry compared to other racial groups, though the reasons for these differences is not known, the authors say. None of the individual tumor genetic differences that were identified are likely to explain significant differences in health outcomes or to prevent Black patients from benefiting from a new generation of precision prostate cancer therapies, the authors say, as long as the therapies are applied equitably.
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