HELP Study


Principal Investigators

NIAAA: Richard Saitz, MD, MPH

NIDA: Jeffrey Samet, MD, MA, MPH

Key Personnel

Ken Freedberg, MD, MSc

Nick Horton, PhD

Suzette Levenson, MPH

Jane Liebschutz, MD, MPH

Lisa Sullivan, MA, PhD


Saitz R, Horton NJ, Larson MJ, Winter M, Samet JH.  Primary medical care and reductions in addiction severity: a prospective cohort study. Addiction. 2005; 100;70-78.

Shanahan CW, Lincoln A, Horton NJ, Saitz R, Winter M, Samet JH. Relationship of Depressive Symptoms and Mental Health to Repeat Detoxification. J. Sub Abuse Treatment. 2005; 29;117-123.

DeAlba I, Samet JH, Saitz R.  Burden of medical illness in drug- and alcohol- dependent persons without primary care. Am J Addictions. 2004; 13:33-45.

Sweeney LP, Samet JH, Larson MJ, Saitz R.  Establishment of a multidisciplinary health evaluation and linkage to primary care (HELP) clinic in a detoxification unit. J Addict Dis. 2004; 23:33-45.

Saitz R, Larson MJ, Horton NJ, Winter M, Samet JH.  Linkage with primary medical care in a prospective cohort of adults with addictions in inpatient detoxification: room for improvement. Health Services Res. 2004; 39:587-606. PMCID: PMC1361026

Wines JD, Saitz R, Horton NJ, Lloyd-Travaglini C, Samet JH.  Suicidal behavior, drug use, and depressive symptoms after detoxification: A two year prospective study. Drug Alc Depend. 2004; 76:S21-S29.

Samet JH, Larson MJ, Horton NJ, Doyle K, Winter M, Saitz R.  Linking alcohol and drug dependent adults to primary medical care: a randomized controlled trial of a multidisciplinary health intervention in a detoxification unit. Addiction. 2003; 98:509-516.

Liebschutz JM, Finley E, Braslins P, Christiansen D, Horton NJ, Samet JH.  Screening for sexually transmitted infections in substance abuse treatment programs. Drug Alc Depend. 2003; 70:93-99.

Rees V, Horton N, Hingson R, Saitz R, Samet JH.  Injury among detoxification patients: alcohol users’ greater risk. Alc Clin Exp Res. 2002; 26:212-217.

Saitz R, Friedmann PD, Sullivan LM, Winter MR, Lloyd-Travaglini C, Moskowitz MA, Samet JH.Professional satisfaction experienced when caring for substance-abusing patients: faculty and resident physician perspectives. J Gen Intern Med. 2002; 17:373-376. PMCID: PMC1495049

Liebschutz JM, Savetsky JB, Saitz R, Horton N, Lloyd-Travaglini C, Samet JH.  The relationship between sexual and physical abuse and substance abuse consequences. J Substance Abuse Treat. 2002; 22:121-128.

Samet JH, Friedmann R, Saitz R.  Benefits of linking primary medical care and substance abuse services: patient, provider, and societal perspectives. Arch Intern Med. 2001; 161:85-91.

Samet JH.  Engaging the HIV-infected substance abuser–the classic academic approach to changing clinical practice: excruciatingly slow, extraneous, and/or effective? Med Gen Med. March 30, 2001.

Friedmann R, Saitz R, Samet JH.  Management of adults recovering from alcohol or other drug problems: relapse prevention in primary care. JAMA. 1998; 279:1227-1231.

Saitz R, Mulvey KP, Samet JH.  The substance-abusing patient and primary care: linkage via the addiction treatment system? Substance Abuse. 1997; 18:187-195.