Cryogenic Electron Microscopy Core
The Boston University Cryogenic Electron Microscopy (BU Cryo-EM) Core Facility is a custom-designed microscope facility located at the Center for Advanced Biomedical Research on the BU Medical Campus. We are committed to providing exceptional instrumentation, training, and advice for researchers looking to answer their scientific questions using cryo-EM/cryo-ET techniques. Our goal is to provide technical and scientific support for the entire cryo-EM/cryo-ET workflow including sample preparation, data collection, and data processing.
Instruments and Services
Description
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Electron Microscope
Glacios-2 Cryo-TEM
- X-FEG electron source
- 12-slot sample autoloader
- Selectris energy filter
- Falcon 4i camera
- Ceta-D camera (for MicroED)
Rates
BU/BUMC Users:
- $28 per hour – Weekdays (Monday 9 a.m.- Friday 2 p.m.)
- $21 per hour – Weekend/Holidays (Friday 2 p.m. – Monday 9.m.)
External Academic Users:
- $75 per hour – Weekdays (Monday 9 a.m.- Friday 2 p.m.)
- $70 per hour – Weekend/Holidays (Friday 2 p.m. – Monday 9.m.)
External Industry Users:
- $264 per hour – Weekdays (Monday 9 a.m.- Friday 2 p.m.)
- $211 per hour – Weekend/Holidays (Friday 2 p.m. – Monday 9.m.)
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Other Instruments
- Vitrobot Mark IV – (two)
- Pelco easiGlow Glow Discharge Unit
- Grid Clipping Stations (two)
- Autoloader Cassette Loading Station
Rates
- BU/BUMC Users: $19 per hour
- External Academic Users: $35 per hour
- External Industry Users: $77 per hour
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Software
- EPU with Multigrid functionality
- CryoSPARC LIVE
- VNC access for remote grid screening and data collection
- SmartEPU with Quality Monitor
- TEM tomography data acquisition software
- SerialEM
- Maps 3 for S/TEM with Correlative Workflow
- MicroED software package
Software use is included with the microscope and instrument use rates.
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How to Schedule
Interested new users, please email the BU Cryo-EM Core Facility at cryoem@bu.edu to schedule an initial consultation to discuss how we can best meet your microscope needs and scientific goals.
Cryogenic Electron Microscopy
Contact
Esther Bullitt, PhD
Professor and Core Facility Director (Team Lead)
bullitt@bu.edu
Chad Hicks, PhD
Cryo-EM Scientist (Core Facility Manager)
hickscw@bu.edu
Christopher Akey, PhD
Professor (Core Facility Advisor)
cakey@bu.edu
Location
Center for Advanced Biomedical Research (CABR)
700 Albany St., Room W-110A
Boston, MA 02118
View BU MAPS