Yuriy O. Alekseyev, PhD

Research Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Yuriy serves as director of BU Microarray Core Resource facility since 2007. Prior to joining BU, Yuriy was a post-doctoral associate with Dr. John Essigmann at MIT where he used animal models to study transcriptional networks affected by a human hepatocarcinogen Aflatoxin B1 and by chemoprevention agents that suppress aflatoxin-induced carcinogenesis.

Yuriy earned a Ph.D. in Biochemistry from the Department of Chemistry at Wayne State University in the laboratory of Dr. Romano, where he studied mechanisms of DNA replication, mutagenesis and repair of carcinogenic lesions. Prior to that he received a M.S. in biotechnology from Moscow Academy of Fine Chemical Technology and worked in Moscow State Scientific Center GNIIGenetica where he studied plant toxins and took part in development of immunotoxins for potential use in cancer therapy and organ transplantation.

Publications

  • Published 6/8/2026

    Kolling Iv FW, Podnar JW, Wilkins O, Fraser CJ, MacDonald ML, Polson SW, Hebert ZT, Chittur SV, Hayden A, Kuentzel M, Heinz M, Huerta GM, Stevenson HS, Karmakar A, Fronick C, Cook L, Vargas S, Xuei X, McGuire P, Zeller M, Zhang Y, Dai R, Wang X, Wai CM, Thimmapuram J, Arora D, Mesa T, Fan J, Alekseyev YO, Cervone F, Williams C, Gorham N, Lemenze A, Goodwin S, Preall J, Whittaker CA. Multisite Assessment of Methods for Cell Preservation Upstream of Single-Cell RNA Sequencing. J Biomol Tech. 2026; 37(2):9-27. PMID: 42281660.

    Read at: PubMed

  • Published 5/5/2026

    Souery W, Wong J, Diaz AA, Xu K, Xiao X, Liu H, Liu G, Gower AC, Alekseyev YO, Billatos E, Lenburg ME. Validation of bronchial airway gene expression associated with bronchiectasis in nasal epithelium. ERJ Open Res. 2026 May; 12(3). PMID: 42094231.

    Read at: PubMed

  • Published 3/24/2026

    Steiner D, Sultan L, Sullivan T, Liu H, Xiao X, LeClerc A, Melvin S, Alekseyev YO, Liu G, Mazzilli SA, Zhang J, Suzuki K, Rieger-Christ K, Burks EJ, Beane J, Lenburg ME. Vascular invasion-associated gene expression is detectable in pre-surgical biopsies of stage I lung adenocarcinoma. Nat Commun. 2026 Mar 24; 17(1). PMID: 41876493.

    Read at: PubMed

  • Published 10/24/2025

    Kolling FW, Podnar JW, Wilkins O, Fraser CJ, MacDonald ML, Polson SW, Herbert ZT, Chittur SV, Hayden A, Kuentzel M, Heinz M, Huerta GM, Stevenson HS, Karmakar A, Fronick C, Cook L, Vargas S, Xuei X, McGuire P, Zeller M, Zhang Y, Dai R, Wang X, Wai CM, Thimmapuram J, Arora D, Mesa T, Fan J, Alekseyev YO, Cervone F, Williams C, Gorham N, Lemenze A, Goodwin S, Preall J, Whittaker CA. Multi-site Assessment of Methods for Cell Preservation Upstream of Single Cell RNA Sequencing. bioRxiv. 2025 Oct 24. PMID: 41279168.

    Read at: PubMed

  • Published 10/2/2025

    Yabaji SM, Zhernovkov V, Araveti PB, Lata S, Rukhlenko OS, Abdullatif SA, Vanvalkenburg A, Alekseyev YO, Ma Q, Dayama G, Lau NC, Johnson WE, Bishai WR, Crossland NA, Campbell JD, Kholodenko BN, Gimelbrant AA, Kobzik L, Kramnik I. Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility. Elife. 2025 Oct 02; 14. PMID: 41037321.

    Read at: PubMed

View All 58 Publications:   View Full Profile in BUMC

Other Positions

  • Member, BU-BMC Cancer Center
    Boston University
  • Director, Microarray Resource Core
    Boston University Chobanian & Avedisian School of Medicine
  • Member, Genome Science Institute
    Boston University
  • Graduate Medical Sciences Educator and Mentor (Primary Mentor of Graduate Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Websites

Education

  • Wayne State University, PhD
  • Moscow State University of Fine Chem Technologies, MS
  • Moscow State University of Fine Chem Technologies, BS

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