Yazdani B. Shaik-Dasthagirisheb, PhD
Research Assistant Professor, Pediatrics
Biography
Microbiologist with extensive experience in bacteriology, immunology, molecularbiology, animal model of bacterial infection, in vivo and in vitro cell assays. Technical skills include detection of bacterial pathogens, serotyping, microbial inhibitory concencentartions (MIC) of clinical samples under GCP (good clinical practices) guidelines, microarrays, Luminex based multiplex immuno assays, protein expression, purification and characterization.
Specialties: Bacterial biofilms and pathogenesis, anaerobic bacteria, pro bacteria, gene discovery, immune response.
Other Positions
- Boston Medical Center
Websites
Education
- Madurai Kamaraj University, PhD
- Sri Krishnadevaraya University, MPhil
- Sri Krishnadevaraya University, MS
- V.R. College, BS
Publications
- Published on 5/2/2025
Zhang Z, Yildirim M, Keskinocak P, Dasthagirisaheb YBS, Hinderstein S, Tran K, Crockett M, Burns M, Johnson H, Popstefanija M, Madoff LC, Pelton SI, Yildirim I. Serotype specific pneumococcal vaccine effectiveness in children with sickle cell disease: A two-decade analysis. Vaccine. 2025 May 02; 56:127193. PMID: 40318350.
Read at: PubMed - Published on 10/4/2024
Kochis EJ, Shaik-Dasthagirisaheb YB, Munarriz N, Kretzmann I, Nahm M, Pelton SI, Lapidot R. Serotype 15C Streptococcus pneumoniae resistant to classical complement deposition and agglutination by polyclonal rabbit anti-capsular 15B sera. Vaccine. 2024 Dec 02; 42(26):126419. PMID: 39368131.
Read at: PubMed - Published on 5/24/2024
Hurst JH, Shaik-Dasthagirisaheb YB, Truong L, Boiditswe SC, Patel SM, Gilchrist J, Maciejewski J, Luinstra K, Smieja M, Steenhoff AP, Cunningham CK, Pelton SI, Kelly MS. Serotype epidemiology and antibiotic resistance of pneumococcal isolates colonizing infants in Botswana (2016-2019). PLoS One. 2024; 19(5):e0302400. PMID: 38787847.
Read at: PubMed - Published on 1/1/2024
Yildirim I, Lapidot R, Shaik-Dasthagirisaheb YB, Hinderstein S, Lee H, Klevens M, Grant L, Arguedas Mohs AG, Cane A, Madoff L, Johnson H, Ivanof C, Burns M, Pelton S. Invasive Pneumococcal Disease After 2 Decades of Pneumococcal Conjugate Vaccine Use. Pediatrics. 2024 Jan 01; 153(1). PMID: 38087952.
Read at: PubMed - Published on 9/29/2023
Sabharwal V, Taglauer E, Demos R, Snyder-Cappione J, Shaik-Dasthagirisaheb YB, Parker-Kelleher S, Hunnewell J, Boateng J, Clarke K, Yuen R, Barnett ED, Wachman EM, Yarrington CD. Comparison of Anti-SARS-CoV-2-Specific Antibody Signatures in Maternal and Infant Blood after COVID-19 Infection versus COVID-19 Vaccination during Pregnancy. Am J Perinatol. 2024 May; 41(S 01):e2970-e2977. PMID: 37774748.
Read at: PubMed - Published on 1/29/2023
Sabharwal V, Demos R, Snyder-Cappione J, Parker SE, Shaik-Dasthagirisaheb Y, Hunnewell J, Boateng J, Clarke K, Yuen R, Barnett E, Yarrington C, Taglauer E, Wachman EM. Cytokine levels in maternal and infant blood after COVID-19 vaccination during pregnancy in comparison with unvaccinated controls. J Reprod Immunol. 2023 Mar; 156:103821. PMID: 36764228.
Read at: PubMed - Published on 1/5/2022
Patel SM, Shaik-Dasthagirisaheb YB, Congdon M, Young RR, Patel MZ, Mazhani T, Boiditswe S, Leburu T, Lechiile K, Arscott-Mills T, Steenhoff AP, Feemster KA, Shah SS, Cunningham CK, Pelton SI, Kelly MS. Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine. PLoS One. 2022; 17(1):e0262225. PMID: 34986196.
Read at: PubMed - Published on 12/31/2018
Shaik Y, Caraffa A, Ronconi G, Lessiani G, Conti P. Impact of polyphenols on mast cells with special emphasis on the effect of quercetin and luteolin. Cent Eur J Immunol. 2018; 43(4):476-481. PMID: 30799996.
Read at: PubMed - Published on 8/22/2018
Francis IP, Islam EA, Gower AC, Shaik-Dasthagirisaheb YB, Gray-Owen SD, Wetzler LM. Murine host response to Neisseria gonorrhoeae upper genital tract infection reveals a common transcriptional signature, plus distinct inflammatory responses that vary between reproductive cycle phases. BMC Genomics. 2018 Aug 22; 19(1):627. PMID: 30134832.
Read at: PubMed - Published on 7/23/2018
Islam EA, Anipindi VC, Francis I, Shaik-Dasthagirisaheb Y, Xu S, Leung N, Sintsova A, Amin M, Kaushic C, Wetzler LM, Gray-Owen SD. Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract. Infect Immun. 2018 08; 86(8). PMID: 29760215.
Read at: PubMed
View 39 more publications: View full profile at BUMC