Microbiologist with extensive experience in bacteriology, immunology, molecularbiology, animal model of bacterial infection, in vivo and in vitro cell assays. Technical skills include detection of bacterial pathogens, serotyping, microbial inhibitory concencentartions (MIC) of clinical samples under GCP (good clinical practices) guidelines, microarrays, Luminex based multiplex immuno assays, protein expression, purification and characterization.
Specialties: Bacterial biofilms and pathogenesis, anaerobic bacteria, pro bacteria, gene discovery, immune response.
- Boston Medical Center
- Madurai Kamaraj University, PhD
- Sri Krishnadevaraya University, MPhil
- Sri Krishnadevaraya University, MS
- V.R. College, BS
- Published on 1/5/2022
Patel SM, Shaik-Dasthagirisaheb YB, Congdon M, Young RR, Patel MZ, Mazhani T, Boiditswe S, Leburu T, Lechiile K, Arscott-Mills T, Steenhoff AP, Feemster KA, Shah SS, Cunningham CK, Pelton SI, Kelly MS. Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine. PLoS One. 2022; 17(1):e0262225. PMID: 34986196.
- Published on 8/22/2018
Francis IP, Islam EA, Gower AC, Shaik-Dasthagirisaheb YB, Gray-Owen SD, Wetzler LM. Murine host response to Neisseria gonorrhoeae upper genital tract infection reveals a common transcriptional signature, plus distinct inflammatory responses that vary between reproductive cycle phases. BMC Genomics. 2018 Aug 22; 19(1):627. PMID: 30134832.
- Published on 7/23/2018
Islam EA, Anipindi VC, Francis I, Shaik-Dasthagirisaheb Y, Xu S, Leung N, Sintsova A, Amin M, Kaushic C, Wetzler LM, Gray-Owen SD. Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract. Infect Immun. 2018 08; 86(8). PMID: 29760215.
- Published on 9/16/2016
Agosto LM, Hirnet JB, Michaels DH, Shaik-Dasthagirisaheb YB, Gibson FC, Viglianti G, Henderson AJ. Porphyromonas gingivalis-mediated signaling through TLR4 mediates persistent HIV infection of primary macrophages. Virology. 2016 Dec; 499:72-81. PMID: 27639573.
- Published on 8/26/2016
Papadopoulos G, Shaik-Dasthagirisaheb YB, Huang N, Viglianti GA, Henderson AJ, Kantarci A, Gibson FC. Immunologic environment influences macrophage response to Porphyromonas gingivalis. Mol Oral Microbiol. 2017 Jun; 32(3):250-261. PMID: 27346827.
- Published on 7/31/2016
Shaik-Dasthagirisaheb YB, Mekasha S, He X, Gibson FC, Ingalls RR. Signaling events in pathogen-induced macrophage foam cell formation. Pathog Dis. 2016 08; 74(6). PMID: 27481727.
- Published on 7/1/2016
Shaik-Dasthagirisaheb YB, Conti P. The Role of Mast Cells in Alzheimer's Disease. Adv Clin Exp Med. 2016 Jul-Aug; 25(4):781-7. PMID: 27629855.
- Published on 12/23/2015
Islam EA, Shaik-Dasthagirisaheb Y, Kaushic C, Wetzler LM, Gray-Owen SD. The reproductive cycle is a pathogenic determinant during gonococcal pelvic inflammatory disease in mice. Mucosal Immunol. 2016 Jul; 9(4):1051-64. PMID: 26693700.
- Published on 6/9/2015
Huang N, Shaik-Dasthagirisaheb YB, LaValley MP, Gibson FC. Liver X receptors contribute to periodontal pathogen-elicited inflammation and oral bone loss. Mol Oral Microbiol. 2015 Dec; 30(6):438-50. PMID: 25946408.
- Published on 6/3/2015
Conti P, Shaik-Dasthagirisaheb YB. Mast Cell Serotonin Immunoregulatory Effects Impacting on Neuronal Function: Implications for Neurodegenerative and Psychiatric Disorders. Neurotox Res. 2015 Aug; 28(2):147-53. PMID: 26038194.
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