Yazdani B. Shaik-Dasthagirisaheb, PhD

Research Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Microbiologist with extensive experience in bacteriology, immunology, molecularbiology, animal model of bacterial infection, in vivo and in vitro cell assays. Technical skills include detection of bacterial pathogens, serotyping, microbial inhibitory concencentartions (MIC) of clinical samples under GCP (good clinical practices) guidelines, microarrays, Luminex based multiplex immuno assays, protein expression, purification and characterization.

Specialties: Bacterial biofilms and pathogenesis, anaerobic bacteria, pro bacteria, gene discovery, immune response.

Publications

  • Published 5/2/2025

    Zhang Z, Yildirim M, Keskinocak P, Dasthagirisaheb YBS, Hinderstein S, Tran K, Crockett M, Burns M, Johnson H, Popstefanija M, Madoff LC, Pelton SI, Yildirim I. Serotype specific pneumococcal vaccine effectiveness in children with sickle cell disease: A two-decade analysis. Vaccine. 2025 May 22; 56:127193. PMID: 40318350.

    Read at: PubMed

  • Published 1/7/2025

    Yildirim M, Keskinocak P, Hinderstein S, Tran K, Dasthagirisaheb YBS, Madoff L, Pelton S, Yildirim I. A comprehensive analysis of serotype-specific invasive capacity, clinical presentations, and mortality trends of invasive pneumococcal disease. Vaccine. 2025 Feb 15; 47:126692. PMID: 39778476.

    Read at: PubMed

  • Published 10/4/2024

    Kochis EJ, Shaik-Dasthagirisaheb YB, Munarriz N, Kretzmann I, Nahm M, Pelton SI, Lapidot R. Serotype 15C Streptococcus pneumoniae resistant to classical complement deposition and agglutination by polyclonal rabbit anti-capsular 15B sera. Vaccine. 2024 Dec 02; 42(26):126419. PMID: 39368131.

    Read at: PubMed

  • Published 5/24/2024

    Hurst JH, Shaik-Dasthagirisaheb YB, Truong L, Boiditswe SC, Patel SM, Gilchrist J, Maciejewski J, Luinstra K, Smieja M, Steenhoff AP, Cunningham CK, Pelton SI, Kelly MS. Serotype epidemiology and antibiotic resistance of pneumococcal isolates colonizing infants in Botswana (2016-2019). PLoS One. 2024; 19(5):e0302400. PMID: 38787847.

    Read at: PubMed

  • Published 1/1/2024

    Yildirim I, Lapidot R, Shaik-Dasthagirisaheb YB, Hinderstein S, Lee H, Klevens M, Grant L, Arguedas Mohs AG, Cane A, Madoff L, Johnson H, Ivanof C, Burns M, Pelton S. Invasive Pneumococcal Disease After 2 Decades of Pneumococcal Conjugate Vaccine Use. Pediatrics. 2024 Jan 01; 153(1). PMID: 38087952.

    Read at: PubMed

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Websites

Education

  • Madurai Kamaraj University, PhD
  • Sri Krishnadevaraya University, MPhil
  • Sri Krishnadevaraya University, MS
  • V.R. College, BS

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