Vladimir A. Botchkarev, MD, PhD

Professor, Dermatology

Vladimir Botchkarev
609 Albany St (J Bldg)


Vladimir Botchkarev, MD, PhD is Research Associate Professor in the Department of Dermatology. He received his medical training at Chuvash State University in Cheboksary, Russian and his doctoral training at People’s Friendship University in Moscow, Russia. He was a recipient of the Research Career Development Award from the Dermatology Foundation and Independent Scientist Award from the National Institutes of Health. He is also a recipient of the research grants from the NIAMS and NCI. His name was included in the books 2000 Outstanding Scientists of the 21st Century, Great Minds of the 21st Century and Who is Who in Medicine. His primary research interests are the molecular mechanisms of hair growth and pathobiology of different forms of hair loss.

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
  • Adjunct Professor, Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine


  • Chuvash State University, MD
  • Peoples' Friendship University of Russia, PhD


  • Published on 4/11/2023

    Botchkarev VA, Fessing MY, Sharov AA. Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation. J Invest Dermatol. 2023 Jul; 143(7):1117-1120. PMID: 37045617.

    Read at: PubMed
  • Published on 1/11/2023

    Chen GD, Fatima I, Xu Q, Rozhkova E, Fessing MY, Mardaryev AN, Sharov AA, Xu GL, Botchkarev VA. DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation. Sci Adv. 2023 Jan 13; 9(2):eabo7605. PMID: 36630508.

    Read at: PubMed
  • Published on 6/9/2022

    Fatima I, Chen G, Botchkareva NV, Sharov AA, Thornton D, Wilkinson HN, Hardman MJ, Grutzkau A, Pedro de Magalhaes J, Seluanov A, Smith ESJ, Gorbunova V, Mardaryev AN, Faulkes CG, Botchkarev VA. Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes. J Invest Dermatol. 2022 Nov; 142(11):2853-2863.e4. PMID: 35691364.

    Read at: PubMed
  • Published on 2/15/2022

    Crouch J, Shvedova M, Thanapaul RJRS, Botchkarev V, Roh D. Epigenetic Regulation of Cellular Senescence. Cells. 2022 02 15; 11(4). PMID: 35203320.

    Read at: PubMed
  • Published on 9/23/2021

    Botchkarev VA, Sharov AA. Histone Deacetylases in the Control of Epidermal Homeostasis: From Chromatin Biology toward Therapy. J Invest Dermatol. 2022 01; 142(1):12-14. PMID: 34565558.

    Read at: PubMed
  • Published on 6/27/2019

    Ahmed MI, Pickup ME, Rimmer AG, Alam M, Mardaryev AN, Poterlowicz K, Botchkareva NV, Botchkarev VA. Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes during Skin Aging. J Invest Dermatol. 2019 12; 139(12):2538-2542.e2. PMID: 31255698.

    Read at: PubMed
  • Published on 8/31/2018

    Castellano-Pellicena I, Uzunbajakava NE, Mignon C, Raafs B, Botchkarev VA, Thornton MJ. Does blue light restore human epidermal barrier function via activation of Opsin during cutaneous wound healing? Lasers Surg Med. 2019 04; 51(4):370-382. PMID: 30168605.

    Read at: PubMed
  • Published on 9/1/2017

    Poterlowicz K, Yarker JL, Malashchuk I, Lajoie BR, Mardaryev AN, Gdula MR, Sharov AA, Kohwi-Shigematsu T, Botchkarev VA, Fessing MY. 5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells. PLoS Genet. 2017 Sep; 13(9):e1006966. PMID: 28863138.

    Read at: PubMed
  • Published on 6/6/2017

    Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A. p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct; 137(10):2157-2167. PMID: 28595999.

    Read at: PubMed
  • Published on 6/2/2017

    Botchkarev VA. Second International Symposium-Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases. J Invest Dermatol. 2017 08; 137(8):1604-1608. PMID: 28583676.

    Read at: PubMed

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