Vijaya B. Kolachalama, PhD, FAHA

Associate Professor, Medicine

Vijaya Kolachalama
72 East Concord Street, Evans 636


Our mission is to create methods to fit the science and not make science fit the methods.

Specifically, we are interested in the following questions that have clinical relevance:
— Neurodegeneration: How can we develop software frameworks that can assist neurology practitioners in various real-world settings?
— Digital pathology: How can we build clinical-grade software tools to complement the pathologist workflow?

We are also interested in the following frameworks that have computational relevance:
— Multimodal learning: Efficient design of generalist AI models that can process multiple modalities of data.
— Representation learning: Construction of efficient neural models on high resolution data to process local and contextual information.

Other Positions

  • Member, Whitaker Cardiovascular Institute, Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Assistant Professor, Computing & Data Sciences Administration, Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences


  • Indian Institute of Technology, Kharagpur, India, BS
  • University of Southampton, UK, PhD


  • Published on 7/4/2024

    Xue C, Kowshik SS, Lteif D, Puducheri S, Jasodanand VH, Zhou OT, Walia AS, Guney OB, Zhang JD, Pham ST, Kaliaev A, Andreu-Arasa VC, Dwyer BC, Farris CW, Hao H, Kedar S, Mian AZ, Murman DL, O'Shea SA, Paul AB, Rohatgi S, Saint-Hilaire MH, Sartor EA, Setty BN, Small JE, Swaminathan A, Taraschenko O, Yuan J, Zhou Y, Zhu S, Karjadi C, Alvin Ang TF, Bargal SA, Plummer BA, Poston KL, Ahangaran M, Au R, Kolachalama VB. AI-based differential diagnosis of dementia etiologies on multimodal data. Nat Med. 2024 Jul 04. PMID: 38965435.

    Read at: PubMed
  • Published on 6/25/2024

    Amini S, Hao B, Yang J, Karjadi C, Kolachalama VB, Au R, Paschalidis IC. Prediction of Alzheimer's disease progression within 6 years using speech: A novel approach leveraging language models. Alzheimers Dement. 2024 Jun 25. PMID: 38924662.

    Read at: PubMed
  • Published on 6/17/2024

    Laudon A, Zou A, Wang Z, Sharma R, Fan X, Ji J, Kim C, Qian Y, Ye Q, Chen H, Henderson JM, Zhang C, Kolachalama VB, Lu W. Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy. bioRxiv. 2024 Jun 17. PMID: 38948787.

    Read at: PubMed
  • Published on 6/4/2024

    Ahangaran M, Zhu H, Li R, Yin L, Jang J, Chaudhry AP, Farrer LA, Au R, Kolachalama VB. DREAMER: a computational framework to evaluate readiness of datasets for machine learning. BMC Med Inform Decis Mak. 2024 Jun 04; 24(1):152. PMID: 38831432.

    Read at: PubMed
  • Published on 6/1/2024

    Lteif D, Sreerama S, Bargal SA, Plummer BA, Au R, Kolachalama VB. Disease-driven domain generalization for neuroimaging-based assessment of Alzheimer's disease. Hum Brain Mapp. 2024 Jun 01; 45(8):e26707. PMID: 38798082.

    Read at: PubMed
  • Published on 5/29/2024

    Ding H, Kim M, Searls E, Sunderaraman P, Anda-Duran I, Low S, Popp Z, Hwang PH, Li Z, Goyal K, Hathaway L, Monteverde J, Rahman S, Igwe A, Kolachalama VB, Au R, Lin H. Corrigendum: Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates. Front Neurol. 2024; 15:1433972. PMID: 38867888.

    Read at: PubMed
  • Published on 4/25/2024

    Shazly T, Eberth JF, Kostelnik CJ, Uline MJ, Chitalia VC, Spinale FG, Alshareef A, Kolachalama VB. Hydrophilic Coating Microstructure Mediates Acute Drug Transfer in Drug-Coated Balloon Therapy. ACS Appl Bio Mater. 2024 May 20; 7(5):3041-3049. PMID: 38661721.

    Read at: PubMed
  • Published on 4/23/2024

    Cordella C, Di Filippo L, Kolachalama VB, Kiran S. Connected Speech Fluency in Poststroke and Progressive Aphasia: A Scoping Review of Quantitative Approaches and Features. Am J Speech Lang Pathol. 2024 Jul 03; 33(4):2091-2128. PMID: 38652820.

    Read at: PubMed
  • Published on 4/17/2024

    Bacon KL, Felson DT, Jafarzadeh SR, Kolachalama VB, Hausdorff JM, Gazit E, Stefanik JJ, Corrigan P, Segal NA, Lewis CE, Nevitt MC, Kumar D. Gait Alterations and Association With Worsening Knee Pain and Physical Function: A Machine Learning Approach With Wearable Sensors in the Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2024 Jul; 76(7):984-992. PMID: 38523250.

    Read at: PubMed
  • Published on 4/16/2024

    Zhang M, Lotfollahzadeh S, Elzinad N, Yang X, Elsadawi M, Gower AC, Belghasem M, Shazly T, Kolachalama VB, Chitalia VC. Alleviating iatrogenic effects of paclitaxel via antiinflammatory treatment. Vasc Med. 2024 Apr 16; 1358863X241231942. PMID: 38623630.

    Read at: PubMed

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