Vijaya B. Kolachalama, PhD, FAHA
Associate Professor, Medicine
Biography
Our mission is to create methods to fit the science and not make science fit the methods.
Specifically, we are interested in the following questions that have clinical relevance:
— Neurodegeneration: How can we develop software frameworks that can assist neurology practitioners in various real-world settings?
— Digital pathology: How can we build clinical-grade software tools to complement the pathologist workflow?
We are also interested in the following frameworks that have computational relevance:
— Multimodal machine learning: Efficient design of AI agents for multimodal data processing with incomplete information.
— Representation learning: Construction of efficient neural networks on high resolution data to process local and contextual information.
Other Positions
- Member, Whitaker Cardiovascular Institute, Boston University
- Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
- Assistant Professor, Computing & Data Sciences Administration, Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- Indian Institute of Technology, Kharagpur, India, BS
- University of Southampton, UK, PhD
Publications
- Published on 1/30/2025
Subramaniam S, Napoleon MA, Lotfollahzadeh S, Kamal MH, Kurniawan H, Elsadawi M, Kenney D, Douam F, Bosmann M, Whelan S, Cabral H, Burks EJ, Zhao G, Kolachalama V, Ravid K, Chitalia V. Tryptophan metabolism reprogramming contributes to the prothrombotic milieu in mice and humans infected with SARS-CoV-2. bioRxiv. 2025 Jan 30. PMID: 39896681.
Read at: PubMed - Published on 12/16/2024
Lauber MV, Bellitti M, Kapadia K, Jasodanand VH, Au R, Kolachalama VB. Global amyloid burden enhances network efficiency of tau propagation in the brain. J Alzheimers Dis. 2024 Dec 16; 13872877241294084. PMID: 39686595.
Read at: PubMed - Published on 11/28/2024
Ahangaran M, Dawalatabad N, Karjadi C, Glass J, Au R, Kolachalama VB. Obfuscation via pitch-shifting for balancing privacy and diagnostic utility in voice-based cognitive assessment. medRxiv. 2024 Nov 28. PMID: 39649616.
Read at: PubMed - Published on 11/18/2024
Ding H, Gifford K, Shih LC, Ho K, Rahman S, Igwe A, Low S, Popp Z, Searls E, Li Z, Madan S, Burk A, Hwang PH, Anda-Duran I, Kolachalama VB, Au R, Lin H. Exploring the Perspectives of Older Adults on a Digital Brain Health Platform Using Natural Language Processing: Cohort Study. JMIR Form Res. 2024 Nov 18; 8:e60453. PMID: 39556805.
Read at: PubMed - Published on 11/2/2024
Kapadia K, Ruwali S, Malav T, Seshadri S, Seidmann A, Press DZ, Kolachalama VB. Enhancing Efficiency with an AI-Augmented Clinician in Neurology. Aging Dis. 2024 Nov 02. PMID: 39500349.
Read at: PubMed - Published on 10/25/2024
Ding H, Ho K, Searls E, Low S, Li Z, Rahman S, Madan S, Igwe A, Popp Z, Burk A, Wu H, Ding Y, Hwang PH, Anda-Duran I, Kolachalama VB, Gifford KA, Shih LC, Au R, Lin H. Assessment of Wearable Device Adherence for Monitoring Physical Activity in Older Adults: Pilot Cohort Study. JMIR Aging. 2024 Oct 25; 7:e60209. PMID: 39454101.
Read at: PubMed - Published on 10/15/2024
Gunes I, Bernstein E, Cowper SE, Panse G, Pradhan N, Camacho LD, Page N, Bundschuh E, Williams A, Carns M, Aren K, Fantus S, Volkmann ER, Bukiri H, Correia C, Wang R, Kolachalama V, Wilson FP, Mawe S, Mahoney JM, Hinchcliff M. Neural network analysis as a novel skin outcome in a trial of belumosudil in patients with systemic sclerosis. Res Sq. 2024 Oct 15. PMID: 39483897.
Read at: PubMed - Published on 9/4/2024
Zheng Y, Conrad RD, Green EJ, Burks EJ, Betke M, Beane JE, Kolachalama VB. Graph Attention-Based Fusion of Pathology Images and Gene Expression for Prediction of Cancer Survival. IEEE Trans Med Imaging. 2024 Sep; 43(9):3085-3097. PMID: 38587959.
Read at: PubMed - Published on 7/12/2024
Jia S, Bit S, Searls E, Claus LA, Fan P, Jasodanand VH, Lauber MV, Veerapaneni D, Wang WM, Au R, Kolachalama VB. MedPodGPT: A multilingual audio-augmented large language model for medical research and education. medRxiv. 2024 Jul 12. PMID: 39040167.
Read at: PubMed - Published on 7/4/2024
Xue C, Kowshik SS, Lteif D, Puducheri S, Jasodanand VH, Zhou OT, Walia AS, Guney OB, Zhang JD, Pham ST, Kaliaev A, Andreu-Arasa VC, Dwyer BC, Farris CW, Hao H, Kedar S, Mian AZ, Murman DL, O'Shea SA, Paul AB, Rohatgi S, Saint-Hilaire MH, Sartor EA, Setty BN, Small JE, Swaminathan A, Taraschenko O, Yuan J, Zhou Y, Zhu S, Karjadi C, Alvin Ang TF, Bargal SA, Plummer BA, Poston KL, Ahangaran M, Au R, Kolachalama VB. AI-based differential diagnosis of dementia etiologies on multimodal data. Nat Med. 2024 Oct; 30(10):2977-2989. PMID: 38965435.
Read at: PubMed
View 95 more publications: View full profile at BUMC