Vijaya B. Kolachalama, PhD, FAHA

Associate Professor, Medicine

Vijaya Kolachalama
72 East Concord Street, Evans 636


Our mission is to create methods to fit the science and not make science fit the methods.

Specifically, we are interested in the following questions that have clinical relevance:
— Neurodegeneration: How can we develop software frameworks that can assist neurology practitioners in various real-world settings?
— Digital pathology: How can we build clinical-grade software tools to complement the pathologist workflow?

We are also interested in the following frameworks that have computational relevance:
— Multimodal learning: Efficient design of generalist AI models that can process multiple modalities of data.
— Representation learning: Construction of efficient neural models on high resolution data to process local and contextual information.

Other Positions

  • Member, Whitaker Cardiovascular Institute, Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Assistant Professor, Computing & Data Sciences Administration, Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences


  • Indian Institute of Technology, Kharagpur, India, BS
  • University of Southampton, UK, PhD


  • Published on 3/24/2024

    Bacon KL, Felson DT, Jafarzadeh SR, Kolachalama VB, Hausdorff JM, Gazit E, Stefanik JJ, Corrigan P, Segal NA, Lewis CE, Nevitt MC, Kumar D. Gait alterations associated with worsening knee pain and physical function: a machine-learning approach with wearable sensors in the Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2024 Mar 24. PMID: 38523250.

    Read at: PubMed
  • Published on 2/22/2024

    Surendran T, Park LK, Lauber MV, Cha B, Jhun RS, Capellini TD, Kumar D, Felson DT, Kolachalama VB. Survival analysis on subchondral bone length for total knee replacement. Skeletal Radiol. 2024 Feb 22. PMID: 38388702.

    Read at: PubMed
  • Published on 2/15/2024

    Ding H, Kim M, Searls E, Sunderaraman P, De Anda-Duran I, Low S, Popp Z, Hwang PH, Li Z, Goyal K, Hathaway L, Monteverde J, Rahman S, Igwe A, Kolachalama VB, Au R, Lin H. Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates. Front Neurol. 2024; 15:1340710. PMID: 38426173.

    Read at: PubMed
  • Published on 2/5/2024

    Ahangaran M, Sun E, Le K, Sun J, Wang WM, Tan TH, Burdine LJ, Dvanajscak Z, Cassol CA, Sharma S, Kolachalama VB. A web-based tool for real-time adequacy assessment of kidney biopsies. medRxiv. 2024 Feb 05. PMID: 38370740.

    Read at: PubMed
  • Published on 1/16/2024

    Popp Z, Low S, Igwe A, Rahman MS, Kim M, Khan R, Oh E, Kumar A, De Anda-Duran I, Ding H, Hwang PH, Sunderaraman P, Shih LC, Lin H, Kolachalama VB, Au R. Shifting From Active to Passive Monitoring of Alzheimer Disease: The State of the Research. J Am Heart Assoc. 2024 Jan 16; 13(2):e031247. PMID: 38226518.

    Read at: PubMed
  • Published on 1/16/2024

    De Anda-Duran I, Sunderaraman P, Searls E, Moukaled S, Jin X, Popp Z, Karjadi C, Hwang PH, Ding H, Devine S, Shih LC, Low S, Lin H, Kolachalama VB, Bazzano L, Libon DJ, Au R. Comparing Cognitive Tests and Smartphone-Based Assessment in 2 US Community-Based Cohorts. J Am Heart Assoc. 2024 Jan 16; 13(2):e032733. PMID: 38226519.

    Read at: PubMed
  • Published on 1/16/2024

    Sunderaraman P, De Anda-Duran I, Karjadi C, Peterson J, Ding H, Devine SA, Shih LC, Popp Z, Low S, Hwang PH, Goyal K, Hathaway L, Monteverde J, Lin H, Kolachalama VB, Au R. Design and Feasibility Analysis of a Smartphone-Based Digital Cognitive Assessment Study in the Framingham Heart Study. J Am Heart Assoc. 2024 Jan 16; 13(2):e031348. PMID: 38226510.

    Read at: PubMed
  • Published on 12/4/2023

    Romano MF, Shih LC, Paschalidis IC, Au R, Kolachalama VB. Large Language Models in Neurology Research and Future Practice. Neurology. 2023 Dec 04; 101(23):1058-1067. PMID: 37816646.

    Read at: PubMed
  • Published on 12/1/2023

    Shazly T, Uline M, Webb C, Pederson B, Eberth JF, Kolachalama VB. Novel Payloads to Mitigate Maladaptive Inward Arterial Remodeling in Drug-Coated Balloon Therapy. J Biomech Eng. 2023 Dec 01; 145(12). PMID: 37542712.

    Read at: PubMed
  • Published on 9/25/2023

    Lteif D, Sreerama S, Bargal SA, Plummer BA, Au R, Kolachalama VB. Disease-driven domain generalization for neuroimaging-based assessment of Alzheimer's disease. medRxiv. 2023 Sep 25. PMID: 37808872.

    Read at: PubMed

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