Victor E. Alvarez

Assistant Professor, Neurology

Victor Alvarez
781.687.3393

Biography

Dr. Alvarez completed his undergraduate degree at Boston College and earned his MD from St. George’s University. He completed residency training in Anatomic and Clinical Pathology at the University of Rochester School of Medicine, fellowship training in Oncologic Surgical Pathology at Roswell Park Cancer Institute, General Surgical Pathology fellowship training at Danbury Hospital, and Neuropathology fellowship training at Brown University. Dr. Alvarez is an Assistant Professor of Neurology at Boston University and manages laboratory and Brain Bank operations at the Bedford VA Hospital and the Boston VA Hospital, Jamaica Plain. He is a member of the New England Veterans Administration Medical Centers (VISN-1) Brain Banks and the Brain Banks for the Boston University Alzheimer’s Disease Center, Center for the Study of Traumatic Encephalopathy, and Framingham Heart Study.

Dr. Alvarez’s research interests center on the relationship between neurotrauma and neurodegenerative diseases. Much of his current work centers on standardizing Brain Banking protocols between the various centers. He is an acting neuropathologist involved with the brain banks for the Boston University Alzheimer Disease Center, CTE Center, and Framingham Heart Study as well as the PTSD brain bank. Dr. Alvarez is a member of the College of American Pathologists and the American Society of Clinical Pathologists.

Other Positions

  • Investigator, Framingham Heart Study
  • Investigator, Alzheimer's Disease Research Center, Boston University
  • Investigator, Chronic Traumatic Encephalopathy Center, Boston University Chobanian & Avedisian School of Medicine
  • Investigator, PTSD Brain Bank, VA Healthcare System

Publications

  • Published on 7/25/2023

    Rosen G, Kirsch D, Horowitz S, Cherry JD, Nicks R, Kelley H, Uretsky M, Dell'Aquila K, Mathias R, Cormier KA, Kubilus CA, Mez J, Tripodis Y, Stein TD, Alvarez VE, Alosco ML, McKee AC, Huber BR. Three dimensional evaluation of cerebrovascular density and branching in chronic traumatic encephalopathy. Acta Neuropathol Commun. 2023 Jul 25; 11(1):123. PMID: 37491342.

    Read at: PubMed
  • Published on 6/20/2023

    Daneshvar DH, Nair ES, Baucom ZH, Rasch A, Abdolmohammadi B, Uretsky M, Saltiel N, Shah A, Jarnagin J, Baugh CM, Martin BM, Palmisano JN, Cherry JD, Alvarez VE, Huber BR, Weuve J, Nowinski CJ, Cantu RC, Zafonte RD, Dwyer B, Crary JF, Goldstein LE, Kowall NW, Katz DI, Stern RA, Tripodis Y, Stein TD, McClean MD, Alosco ML, McKee AC, Mez J. Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males. Nat Commun. 2023 Jun 20; 14(1):3470. PMID: 37340004.

    Read at: PubMed
  • Published on 3/6/2023

    Alosco ML, Ly M, Mosaheb S, Saltiel N, Uretsky M, Tripodis Y, Martin B, Palmisano J, Delano-Wood L, Bondi MW, Meng G, Xia W, Daley S, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Stern RA, Alvarez VE, Mez J, Huber BR, McKee AC, Stein TD. Decreased myelin proteins in brain donors exposed to football-related repetitive head impacts. Brain Commun. 2023; 5(2):fcad019. PMID: 36895961.

    Read at: PubMed
  • Published on 2/10/2023

    McKee AC, Stein TD, Huber BR, Crary JF, Bieniek K, Dickson D, Alvarez VE, Cherry JD, Farrell K, Butler M, Uretsky M, Abdolmohammadi B, Alosco ML, Tripodis Y, Mez J, Daneshvar DH. Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts. Acta Neuropathol. 2023 Apr; 145(4):371-394. PMID: 36759368.

    Read at: PubMed
  • Published on 1/21/2023

    Nicks R, Clement NF, Alvarez VE, Tripodis Y, Baucom ZH, Huber BR, Mez J, Alosco ML, Aytan N, Cherry JD, Cormier KA, Kubilius C, Mathias R, Svirsky SE, Pothast MJ, Hildebrandt AM, Chung J, Han X, Crary JF, McKee AC, Frosch MP, Stein TD. Repetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis. Acta Neuropathol. 2023 Apr; 145(4):395-408. PMID: 36681782.

    Read at: PubMed
  • Published on 1/20/2023

    Kirsch D, Shah A, Dixon E, Kelley H, Cherry JD, Xia W, Daley S, Aytan N, Cormier K, Kubilus C, Mathias R, Alvarez VE, Huber BR, McKee AC, Stein TD. Vascular injury is associated with repetitive head impacts and tau pathology in chronic traumatic encephalopathy. J Neuropathol Exp Neurol. 2023 Jan 20; 82(2):127-139. PMID: 36617181.

    Read at: PubMed
  • Published on 1/1/2023

    Vig V, Garg I, Tuz-Zahra F, Xu J, Tripodis Y, Nicks R, Xia W, Alvarez VE, Alosco ML, Stein TD, Subramanian ML. Vitreous Humor Biomarkers Reflect Pathological Changes in the Brain for Alzheimer's Disease and Chronic Traumatic Encephalopathy. J Alzheimers Dis. 2023; 93(3):1181-1193. PMID: 37182888.

    Read at: PubMed
  • Published on 9/19/2022

    Farrell K, Iida MA, Cherry JD, Casella A, Stein TD, Bieniek KF, Walker JM, Richardson TE, White CL, Alvarez VE, Huber BR, Dickson DW, Insausti R, Dams-O'Connor K, McKee AC, Crary JF. Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy. J Neuropathol Exp Neurol. 2022 Sep 19; 81(10):781-789. PMID: 36004533.

    Read at: PubMed
  • Published on 9/19/2022

    Butler MLMD, Dixon E, Stein TD, Alvarez VE, Huber B, Buckland ME, McKee AC, Cherry JD. Tau Pathology in Chronic Traumatic Encephalopathy is Primarily Neuronal. J Neuropathol Exp Neurol. 2022 Sep 19; 81(10):773-780. PMID: 35903039.

    Read at: PubMed
  • Published on 8/1/2022

    Atherton K, Han X, Chung J, Cherry JD, Baucom Z, Saltiel N, Nair E, Abdolmohammadi B, Uretsky M, Khan MM, Shea C, Durape S, Martin BM, Palmisano JN, Farrell K, Nowinski CJ, Alvarez VE, Dwyer B, Daneshvar DH, Katz DI, Goldstein LE, Cantu RC, Kowall NW, Alosco ML, Huber BR, Tripodis Y, Crary JF, Farrer L, Stern RA, Stein TD, McKee AC, Mez J. Association of APOE Genotypes and Chronic Traumatic Encephalopathy. JAMA Neurol. 2022 Aug 01; 79(8):787-796. PMID: 35759276.

    Read at: PubMed

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