Tuhina Neogi, MD, PhD
Professor, Medicine
Biography
I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 300 peer-reviewed publications to date. I am a past chair of the FDA Arthritis Advisory Committee, serve(d) on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year), and the 2022 OARSI Clinical Research Award (in recognition of important contributions to OA research). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I also developed and led the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.
Expertise includes:
– Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
– Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
– Classification criteria and outcome measures in rheumatic diseases.
– Novel methodology to address challenging epidemiologic issues
Other Positions
- Professor, Epidemiology, Boston University School of Public Health
- Chief, Rheumatology, Medicine, Boston Medical Center
- Investigator, Framingham Heart Study
- Member, Arthritis & Autoimmune Diseases Research Center, Boston University
- Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
- Section Chief of Rheumatology, Rheumatology, Medicine, Boston University Chobanian & Avedisian School of Medicine
Education
- University of Toronto, MD
- Boston University School of Public Health, PhD
- McMaster University, BS
Publications
- Published on 6/24/2024
Barry A, Helget LN, Androsenko M, Wu H, Kramer B, Newcomb JA, Brophy MT, Davis-Karim A, England BR, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, Merriman TR, O'Dell JR, Mikuls TR. Comparison of Gout Flares With the Initiation of Treat-to-Target Allopurinol and Febuxostat: A Post-Hoc Analysis of a Randomized Multicenter Trial. Arthritis Rheumatol. 2024 Jun 24. PMID: 38925627.
Read at: PubMed - Published on 6/23/2024
Aoyagi K, Neogi T. Reply. Arthritis Care Res (Hoboken). 2024 Jun 23. PMID: 38922766.
Read at: PubMed - Published on 6/19/2024
Helget LN, Davis-Karim A, O'Dell JR, Mikuls TR, Newcomb JA, Androsenko M, Brophy MT, England BR, Ferguson R, Pillinger MH, Neogi T, Wu H, Palevsky PM. Efficacy and Safety of Allopurinol and Febuxostat in Patients With Gout and CKD: Subgroup Analysis of the STOP Gout Trial. Am J Kidney Dis. 2024 Jun 19. PMID: 38906504.
Read at: PubMed - Published on 5/18/2024
Lee S, Neogi T, McGinley B, Wang N, Frey Law L, Torabian KA, Aoyagi K, Stefanik JJ, Carlesso LC, Hausdorff JM, Gazit E, Segal NA, Lewis CE, Nevitt MC, Kumar D. Associations of pain sensitivity and conditioned pain modulation with physical activity: findings from the Multicenter Osteoarthritis Study (MOST). Osteoarthritis Cartilage. 2024 May 18. PMID: 38763431.
Read at: PubMed - Published on 4/30/2024
Mulrooney E, Neogi T, Dagfinrud H, Hammer HB, Pettersen PS, Kvien TK, Magnusson K, Haugen IK. Hand osteoarthritis phenotypes based on a biopsychosocial approach, and their associations with cross-sectional and longitudinal pain. Osteoarthritis Cartilage. 2024 Apr 30. PMID: 38697510.
Read at: PubMed - Published on 4/2/2024
Liew JW, Jarraya M, Guermazi A, Lynch J, Felson D, Nevitt M, Lewis CE, Torner J, Roemer FW, Crema MD, Wang N, Becce F, Rabasa G, Pascart T, Neogi T. Intra-Articular Mineralization on Computerized Tomography of the Knee and Risk of Cartilage Damage: The Multicenter Osteoarthritis Study. Arthritis Rheumatol. 2024 Jul; 76(7):1054-1061. PMID: 38369918.
Read at: PubMed - Published on 3/2/2024
Mahmoudian A, King LK, Liew JW, Wang Q, Appleton CT, Englund M, Haugen IK, Lohmander LS, Runhaar J, Turkiewicz A, Neogi T, Hawker GA. Timing is everything: Towards classification criteria for early-stage symptomatic knee osteoarthritis. Osteoarthritis Cartilage. 2024 Jun; 32(6):649-653. PMID: 38437945.
Read at: PubMed - Published on 12/28/2023
Aoyagi K, Jafarzadeh SR, Carlesso L, Frey Law L, Lewis CE, Nevitt M, Neogi T. Mediating Effect of Pain Sensitization on the Paradoxical Relation of Taking Opioids to Pain Severity in Knee Osteoarthritis: The Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2024 Mar; 76(3):403-408. PMID: 37750238.
Read at: PubMed - Published on 12/26/2023
Helget LN, O'Dell JR, Newcomb JA, Androsenko M, Brophy MT, Davis-Karim A, England BR, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, Wu H, Kramer B, Mikuls TR. Determinants of Achieving Serum Urate Goal with Treat-to-Target Urate-Lowering Therapy in Gout. Arthritis Rheumatol. 2024 Apr; 76(4):638-646. PMID: 37842953.
Read at: PubMed - Published on 10/15/2023
Liew JW, Jarraya M, Guermazi A, Lynch J, Wang N, Rabasa G, Jafarzadeh SR, Nevitt M, Torner J, Lewis CE, Felson DT, Neogi T. Relation of Intra-Articular Mineralization to Knee Pain in Knee Osteoarthritis: A Longitudinal Analysis in the MOST Study. Arthritis Rheumatol. 2023 Dec; 75(12):2161-2168. PMID: 37410792.
Read at: PubMed
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