Toby C. Chai, MD

Richard K. Babayan, MD Professor, Urology

Toby Chai


Toby C. Chai, MD, is Chief of Urology at Boston Medical Center, and Professor and Chair of the Department of Urology at Chobanian and Avedisian School of Medicine. He also serves as President of Boston University Medical Center Urologists, Inc.

Dr. Chai was previously Professor of Urology and Obstetrics, Gynecology, and Reproductive Sciences at Yale University School of Medicine. He served as Vice Chair of Research in the Department of Urology and Co-Director of the Female Pelvic Medicine and Reconstructive Surgery Program at Yale New Haven Hospital.

Dr. Chai completed his medical degree at Indiana University School of Medicine, his urology residency at University of Michigan Medical Center, and a fellowship at University of Virginia. Prior to joining Yale, he held the John D. Young Professorship in Urology at the University of Maryland School of Medicine.

Dr. Chai has been PI on NIH R01, P20 and U01 grants. He has published 150 papers, reviews, and medical texts. He serves on the editorial board of the American Journal of Physiology – Renal, and is Co-Editor-in-Chief of Bladder and Associate Editor for Journal of Urology. His peers have recognized his significant contributions to the field by honoring him with the American Urological Association’s Victor A. Politano Award for outstanding work in treatment of urinary incontinence and innovations in bladder research and the Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction’s Distinguished Service Award for outstanding contributions to urodynamics, female urology and voiding dysfunction, and exemplary service to the Society.

Other Positions

  • Chair, Urology, Boston University Chobanian & Avedisian School of Medicine
  • Chief, Urology, Boston Medical Center
  • President, Boston University Medical Center Urologists, Inc.


  • Indiana University School of Medicine, MD
  • Yale University, MA
  • Johns Hopkins University, BA


  • Published on 4/5/2024

    Donohoo N, Orlando A, Chai TC. Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is Imprecise-Time to Cleave into IC and BPS as Separate Conditions. J Urol. 2024 Apr 05; 101097JU0000000000003953. PMID: 38578287.

    Read at: PubMed
  • Published on 6/24/2022

    Assel M, Chai TC. When Is Using a Prediction Model Better Than No Model to Inform Clinical Decision Making? J Urol. 2022 09; 208(3):530-533. PMID: 35748649.

    Read at: PubMed
  • Published on 7/1/2021

    Chai TC. RE: Intraoperative Evaluation of Urinary Tract Injuries at the Time of Pelvic Surgery: A Systematic Review. Female Pelvic Med Reconstr Surg. 2021 07 01; 27(7):e605. PMID: 33411453.

    Read at: PubMed
  • Published on 5/16/2021

    Zhu K, Hill WG, Li F, Shi B, Chai TC. Urine and Tissue Bacterial Loads Correlate With Voiding Behaviors in a Murine Urinary Tract Infection Model. Urology. 2021 08; 154:344.e1-344.e7. PMID: 34010680.

    Read at: PubMed
  • Published on 5/4/2021

    Powell T, Staib L, Liu B, Bhatia S, Chai T, Ayyagari R. Voiding and Storage Domain-Specific Symptom Score Outcomes After Prostate Artery Embolization for Lower Urinary Tract Symptoms and Urinary Retention. Urology. 2021 10; 156:216-224. PMID: 33961894.

    Read at: PubMed
  • Published on 4/1/2021

    Biebel MG, Pate WR, Chai TC. Transurethral resection of prostatic abscess. Can J Urol. 2021 04; 28(2):10638-10642. PMID: 33872565.

    Read at: PubMed
  • Published on 2/3/2021

    Li Y, Liu Y, Gao Z, Zhang L, Chen L, Wu Z, Liu Q, Wang S, Zhou N, Chai TC, Shi B. Single-cell transcriptomes of mouse bladder urothelium uncover novel cell type markers and urothelial differentiation characteristics. Cell Prolif. 2021 Apr; 54(4):e13007. PMID: 33538002.

    Read at: PubMed
  • Published on 3/19/2020

    Zhu K, Hill WG, Li F, Shi B, Chai TC. Early Increased Urinary IL-2 and IL-10 Levels Were Associated With Development of Chronic UTI in a Murine Model. Urology. 2020 07; 141:188.e1-188.e6. PMID: 32201154.

    Read at: PubMed
  • Published on 1/16/2020

    Rovner E, Chai TC, Jacobs S, Christ G, Andersson KE, Efros M, Nitti V, Davies K, McCullough AR, Melman A. Evaluating the safety and potential activity of URO-902 (hMaxi-K) gene transfer by intravesical instillation or direct injection into the bladder wall in female participants with idiopathic (non-neurogenic) overactive bladder syndrome and detrusor overactivity from two double-blind, imbalanced, placebo-controlled randomized phase 1 trials. Neurourol Urodyn. 2020 02; 39(2):744-753. PMID: 31945197.

    Read at: PubMed
  • Published on 11/23/2019

    Ayyagari R, Powell T, Staib L, Chapiro J, Raja A, Bhatia S, Chai T, Schoenberger S, Devito R. Prostatic Artery Embolization Using 100-300-µm Trisacryl Gelatin Microspheres to Treat Lower Urinary Tract Symptoms Attributable to Benign Prostatic Hyperplasia: A Single-Center Outcomes Analysis with Medium-Term Follow-up. J Vasc Interv Radiol. 2020 Jan; 31(1):99-107. PMID: 31771896.

    Read at: PubMed

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