Sherral A. Devine, PhD

Research Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Devine earned her BA in psychology at DePauw University, and then her MA and PhD in clinical psychology at Bowling Green State University in Ohio. She completed her clinical internship at the Boston VA Medical Center/Tufts University Consortium and then completed a three-year postdoctoral program in clinical neuropsychology, providing services to veterans and civilians with a wide range of neurological and psychiatric disorders. Dr. Devine has worked in a research setting since completing her postdoctoral work, and she has also worked intermittently in clinical settings, evaluating individuals with a variety of cognitive disorders. These clients have been as young as 12, but Dr. Devine’s primary interest is in a geriatric population.

In 1999, Dr. Devine started working as a clinical neuropsychologist at the Framingham Heart Study (FHS), where research on cognitive functioning was greatly expanding. Through the years, she has collaborated with Dr. Rhoda Au in applying the Boston Process Approach (BPA) to research using neuropsychological tests. BPA goes beyond the typically used quantitative scores, adding the wealth of information available in qualitative aspects of an individual’s performance on cognitive tests. Although widely used in clinical settings, research using BPA is severely limited, given the challenges of operationalizing qualitative aspects of an individual’s behavior while taking cognitive tests. Dr. Devine has especially enjoyed this challenge, as well as providing training and supervision to testers to ensure reliable and consistent coding of behavior. This has been important because of the large number of testers who have been involved with FHS over the years. In addition to BPA generally, Dr. Devine been especially interested in examining the extensive information that can be gleaned from the Clock Drawing Test, a quick and simple task that involves asking an individual to draw a clock and set the hands to a specified time, and to copy a pre-drawn clock. Dr. Devine is involved with the research at FHS into identification of cognitive biomarkers, especially those caught digitally (i.e., with audio recorders and digital pens), that may reveal risk in the very early (i.e., pre- pre-clinical) stages of dementia.

Publications

  • Published 4/1/2025

    Ding H, Lyu C, Karjadi C, Sunderaraman P, Young CB, Mormino EC, Low S, Devine S, Gifford K, Au R, Lin H. Association of the digital clock drawing test with amyloid and tau PET biomarkers in low age risk adults. Sci Rep. 2025 Apr 01; 15(1):11104. PMID: 40169870.

    Read at: PubMed

  • Published 3/2/2025

    Yang J, Ding H, Li Y, Ang TFA, Devine S, Liu Y, Qiu W, Au R, Ma J, Liu C. Association of mid-age Life's Essential 8 score with digital cognitive performance and incident Alzheimer's disease: The Framingham Heart Study. J Alzheimers Dis. 2025 Mar; 104(2):498-508. PMID: 40025717.

    Read at: PubMed

  • Published 2/13/2025

    Kang M, Ang TFA, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi SE, Klinedinst B, Nakano C, Dumitrescu LC, Hohman TJ, Cuccaro ML, Saykin AJ, Kukull WA, Bennett DA, Wang LS, Mayeux RP, Haines JL, Pericak-Vance MA, Schellenberg GD, Crane PK, Au R, Lunetta KL, Mez J, Farrer LA. Genome-wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measures. medRxiv. 2025 Feb 13. PMID: 39990565.

    Read at: PubMed

  • Published 10/15/2024

    Yuan J, Tao Q, Ang TFA, Liu C, Devine S, Auerbach SH, Mez J, Farrer LA, Qiu WQ, Au R. The Relationship between Framingham Stroke Risk Profile on Incident Dementia and Alzheimer's Disease: A 40-Year Follow-Up Study Highlighting Female Vulnerability. Ann Neurol. 2024 Dec; 96(6):1124-1134. PMID: 39404028.

    Read at: PubMed

  • Published 10/1/2024

    Kang M, Li C, Mahajan A, Spat-Lemus J, Durape S, Chen J, Gurnani AS, Devine S, Auerbach SH, Ang TFA, Sherva R, Qiu WQ, Lunetta KL, Au R, Farrer LA, Mez J. Subjective Cognitive Decline Plus and Longitudinal Assessment and Risk for Cognitive Impairment. JAMA Psychiatry. 2024 Oct 01; 81(10):993-1002. PMID: 38959008.

    Read at: PubMed

Other Positions

  • Research Assistant Professor, Neurology
    Boston University Chobanian & Avedisian School of Medicine
  • Center Faculty Member, Anatomy & Neurobiology
    Boston University Chobanian & Avedisian School of Medicine

Education

  • Bowling Green State University, PhD
  • Bowling Green State University, MA
  • DePauw University, BA