Saran Lotfollahzadeh

Instructor, Boston University Chobanian & Avedisian School of Medicine

Biography

I am a physician-scientist. I underwent medical school training and embarked on an integrated five-year general and vascular surgery residency program followed by a clinical fellowship in Pediatric and Vascular Surgery focusing on cardiovascular complications and hemodialysis access in patients with end-stage kidney disease. In doing so, I developed a deep appreciation of the impact of vascular morbidities on overall disease burden. During my clinical training, I performed epidemiological research in an interdisciplinary setup as a country lead with a group in King’s College, UK. However, I was not exposed to the power of translational research. Upon joining the lab of Dr. Chitalia at the Boston University School of Medicine, I was exposed to how to bring clinically relevant problems to testing them bench and dissect mechanistically. With my clinical experience in vascular medicine, oncosurgery, and research experience in thrombosis, I was granted an AHA SFRN fellowship on cardio-oncology. I have developed various animal models, such as different models of femoral artery ligation for hind limb ischemia and inferior vena cava ligation assays in mice as a model of deep vein thrombosis. My passion is to understand molecular pathobiology driving such fundamental processes and amalgamate the clinical experience with translational science focusing on cardiometabolic risk factors.

Publications

  • Published 3/24/2026

    Lotfollahzadeh S, Jalihal P, A'amar O, Chung JY, Howard M, Oros E, Rodriguez-Diaz E, Belghasem M, Kumar A, Malik S, Francis J, Chitalia VC, Bigio IJ. Quantitative Assessment of Kidney Interstitial Fibrosis Using an Intrarenal Optical Spectroscopy. Kidney360. 2026 Mar 24. PMID: 41874566.

    Read at: PubMed

  • Published 2/13/2026

    Decker JW, BaniHani D, HonShideler C, Lotfollahzadeh S, Wu Wong DJ, Farber A, Siracuse JJ, Idrees N, Dember L, Bader M, Ganguli S, Kolachalama V, Shazly T, Chitalia VC. Intravascular Ultrasound is More Accurate Than Angiography in Arteriovenous Vascular Access Lesions. Kidney360. 2026 Feb 13. PMID: 41686504.

    Read at: PubMed

  • Published 1/5/2026

    Subramaniam S, Napoleon MA, Lotfollahzadeh S, Kamal MH, Kurniawan H, Francis C, Elsadawi M, Wu Wong DJ, Kenney D, Douam F, Bosmann M, Whelan SA, Cabral H, Burks EJ, Zhao G, Kolachalama VB, Ravid K, Chitalia VC. Tryptophan metabolism reprogramming potentially contributes to the prothrombotic milieu in mice and humans with SARS-CoV-2. Blood Vessel Thromb Hemost. 2026 Feb; 3(1):100128. PMID: 41743170.

    Read at: PubMed

  • Published 11/3/2025

    Saran Lotfollahzadeh, MD,MSc, Jeffrey Siracuse, BA, MD, Howard Cabral, PhD, MPH, Marina Malikova, PhD,MBA, Nazish Sayed, MD, PhD, and Vipul Chitalia, MD, PhD. A murine model of cardiovascular-kidney-metabolic syndrome demonstrates compromised limb function in the ischemic hind limb. 2025.

    Read at: Custom

  • Published 10/14/2025

    Lotfollahzadeh S, Jose A, Yang X, Bathla T, Lazowski A, Hoekstra I, Sethuraman K, Potluri S, Dulberger KN, La J, Fillmore NR, Piqueras MDC, Lee N, Cabral H, Ravid K, Chitalia VC. Dietary tryptophan augments cancer-associated venous thrombogenicity mitigated by indoleamine 2,3-dioxygenase 1 inhibition. Blood Adv. 2025 Oct 14; 9(19):4910-4923. PMID: 40668615.

    Read at: PubMed

View All 44 Publications:   View Full Profile in BUMC

Websites

View all profiles