Philipp Mews, PhD

Assistant Professor, Physiology & Biophysics

Philipp Mews
617.358.1111

Education

  • University of Pennsylvania School of Medicine, PhD
  • Freie Universität Berlin, BS

Publications

  • Published on 9/19/2023

    Browne CJ, Mews P, Zhou X, Holt LM, Estill M, Futamura R, Schaefer A, Kenny PJ, Hurd YL, Shen L, Zhang B, Nestler EJ. Shared and divergent transcriptomic regulation in nucleus accumbens D1 and D2 medium spiny neurons by cocaine and morphine. bioRxiv. 2023 Sep 19. PMID: 37781621.

    Read at: PubMed
  • Published on 3/7/2023

    Godino A, Salery M, Durand-de Cuttoli R, Estill MS, Holt LM, Futamura R, Browne CJ, Mews P, Hamilton PJ, Neve RL, Shen L, Russo SJ, Nestler EJ. Transcriptional control of nucleus accumbens neuronal excitability by retinoid X receptor alpha tunes sensitivity to drug rewards. Neuron. 2023 May 03; 111(9):1453-1467.e7. PMID: 36889314.

    Read at: PubMed
  • Published on 3/1/2023

    Emerson SD, Chevée M, Mews P, Calipari ES. The transcriptional response to acute cocaine is inverted in male mice with a history of cocaine self-administration and withdrawal throughout the mesocorticolimbic system. Mol Cell Neurosci. 2023 Jun; 125:103823. PMID: 36868542.

    Read at: PubMed
  • Published on 2/10/2023

    Mews P, Cunningham AM, Scarpa J, Ramakrishnan A, Hicks EM, Bolnick S, Garamszegi S, Shen L, Mash DC, Nestler EJ. Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models. Sci Adv. 2023 Feb 10; 9(6):eadd8946. PMID: 36763659.

    Read at: PubMed
  • Published on 8/3/2022

    Alexander DC, Corman T, Mendoza M, Glass A, Belity T, Wu R, Campbell RR, Han J, Keiser AA, Winkler J, Wood MA, Kim T, Garcia BA, Cohen H, Mews P, Egervari G, Berger SL. Targeting acetyl-CoA metabolism attenuates the formation of fear memories through reduced activity-dependent histone acetylation. Proc Natl Acad Sci U S A. 2022 Aug 09; 119(32):e2114758119. PMID: 35921439.

    Read at: PubMed
  • Published on 7/28/2022

    van der Zee YY, Eijssen LMT, Mews P, Ramakrishnan A, Alvarez K, Lardner CK, Cates HM, Walker DM, Torres-Berrío A, Browne CJ, Cunningham A, Cathomas F, Kronman H, Parise EM, de Nijs L, Shen L, Murrough JW, Rutten BPF, Nestler EJ, Issler O. Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression. Mol Psychiatry. 2022 Nov; 27(11):4536-4549. PMID: 35902629.

    Read at: PubMed
  • Published on 4/7/2022

    Mews P. Targeting memories to treat trauma. Science. 2022 Apr 08; 376(6589):147. PMID: 35389804.

    Read at: PubMed
  • Published on 5/1/2021

    Kronman H, Torres-Berrío A, Sidoli S, Issler O, Godino A, Ramakrishnan A, Mews P, Lardner CK, Parise EM, Walker DM, van der Zee YY, Browne CJ, Boyce BF, Neve R, Garcia BA, Shen L, Peña CJ, Nestler EJ. Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons. Nat Neurosci. 2021 May; 24(5):753-754. PMID: 33833436.

    Read at: PubMed
  • Published on 3/15/2021

    Kronman H, Torres-Berrío A, Sidoli S, Issler O, Godino A, Ramakrishnan A, Mews P, Lardner CK, Parise EM, Walker DM, van der Zee YY, Browne CJ, Boyce BF, Neve R, Garcia BA, Shen L, Peña CJ, Nestler EJ. Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons. Nat Neurosci. 2021 May; 24(5):667-676. PMID: 33723435.

    Read at: PubMed
  • Published on 2/27/2021

    van der Zee YY, Lardner CK, Parise EM, Mews P, Ramakrishnan A, Patel V, Teague CD, Salery M, Walker DM, Browne CJ, Labonté B, Parise LF, Kronman H, Penã CJ, Torres-Berrío A, Duffy JE, de Nijs L, Eijssen LMT, Shen L, Rutten B, Issler O, Nestler EJ. Sex-Specific Role for SLIT1 in Regulating Stress Susceptibility. Biol Psychiatry. 2022 Jan 01; 91(1):81-91. PMID: 33896623.

    Read at: PubMed

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