Nicole Z Spence, MD

Assistant Professor, Anesthesiology

Nicole Spence


Dr. Nicole Spence is a board certified anesthesiologist. She received her medical degree from Rutgers-Robert Wood Johnson Medical School and completed her residency at New York-Presbyterian Hospital-Columbia University, New York, NY and an accredited regional anesthesiology/acute pain management fellowship at Massachusetts General Hospital, Boston, MA.

Dr. Spence is committed to improving perioperative pain control, patient satisfaction, encompassing regional anesthetic techniques, optimizing narcotic sparing modalities, exploring anesthesia and women’s health, and fostering patient and trainee education. She spends most of her clinical practice as an orthopedic, obstetric, regional, and perioperative pain anesthesiologist and is committed to teaching students and trainees.


  • Robert Wood Johnson Medical School, MD
  • Emory University, BS


  • Published on 5/19/2023

    Holland E, Gibbs L, Spence NZ, Young M, Werler MM, Guang Z, Saia K, Bateman BT, Achu R, Wachman EM. A comparison of postpartum opioid consumption and opioid discharge prescriptions among opioid-naïve patients and those with opioid use disorder. Am J Obstet Gynecol MFM. 2023 Aug; 5(8):101025. PMID: 37211090.

    Read at: PubMed
  • Published on 4/25/2023

    Wong ML, Achu RA, Spence NZ, White KO. Feasibility of methadone for pain relief in first trimester abortion (Boston, Massachusetts 2022). Contraception. 2023 Sep; 125:110052. PMID: 37105280.

    Read at: PubMed
  • Published on 6/2/2022

    Vasudevan A, Achu R, Perry A, Yarrington C, Norris M, Tracy L, Spence NZ. Impact of pregnancy on airway complications after intubation for COVID-19 infection: A case series. Am J Otolaryngol. 2022 Sep-Oct; 43(5):103522. PMID: 35696815.

    Read at: PubMed
  • Published on 1/1/2022

    Tabbara AK, Krishnan S, Vaynberg E, Spence NZ, Lambert DH. Intraoperative methadone: Proceed with care. J Opioid Manag. 2022; 18(4):377-383. PMID: 36052934.

    Read at: PubMed
  • Published on 8/1/2021

    Katz D, Bateman BT, Kjaer K, Turner DP, Spence NZ, Habib AS, George RB, Toledano RD, Grant G, Madden HE, Butwick AJ, Lynde G, Minehart RD, Beilin Y, Houle TT, Sharpe EE, Kodali B, Bharadwaj S, Farber MK, Palanisamy A, Prabhu M, Gonzales NY, Landau R, Leffert L. The Society for Obstetric Anesthesia and Perinatology Coronavirus Disease 2019 Registry: An Analysis of Outcomes Among Pregnant Women Delivering During the Initial Severe Acute Respiratory Syndrome Coronavirus-2 Outbreak in the United States. Anesth Analg. 2021 08 01; 133(2):462-473. PMID: 33830956.

    Read at: PubMed
  • Published on 3/16/2021

    Hyland SJ, Brockhaus KK, Vincent WR, Spence NZ, Lucki MM, Howkins MJ, Cleary RK. Perioperative Pain Management and Opioid Stewardship: A Practical Guide. Healthcare (Basel). 2021 Mar 16; 9(3). PMID: 33809571.

    Read at: PubMed
  • Published on 9/2/2020

    Spence NZ, Lu ME, Larson AR, Ortega R. COVID-19 and occupational skin hazards for anaesthetists. Br J Anaesth. 2020 12; 125(6):e476-e478. PMID: 32977956.

    Read at: PubMed
  • Published on 7/17/2020

    Canelli R, Spence N, Kumar N, Rodriguez G, Gonzalez M. The Ventilator Management Team: Repurposing Anesthesia Workstations and Personnel to Combat COVID-19. J Intensive Care Med. 2020 Sep; 35(9):927-932. PMID: 32677498.

    Read at: PubMed
  • Published on 1/1/2020

    Spence NZ. Specialty Imaging: Acute and Chronic Pain Intervention (McCarthy, Walker, Vazquez eds.). Various chapters. Elsevier. 2020.

  • Published on 1/1/2018

    Spence NZ. 1000 Questions to Blast the Anesthesiology Boards (Berg SM, Bittner EA, Schnur M eds.). Orthopedic Anesthesia. Lippincott Williams & Wilkins. Philadelphia. 2018.

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