Nicole L Spartano, PhD

Assistant Professor, Medicine

Nicole Spartano
75 E. Newton St

Biography

Nicole Spartano, PhD is an Assistant Professor of Medicine in Endocrinology, Diabetes, Nutrition and Weight Management at the Chobanian and Avedisian School of Medicine. She serves as the Director of the Glucose Monitoring Station at the Framingham Heart Study. This study is funded through an R01 from the National Institute of Diabetes and Digestive and Kidney Diseases (Spartano, PI) to use continuous glucose monitors in a non-diabetic population to measure glucose patterns that may predict the development of diabetes. She also serves as the Co-Director of the Physical Activity Station at the Framingham Heart Study, overseeing data collection using accelerometers (fitness trackers). She has received funding from the American Heart Association and Alzheimer’s Association to understand the impact of physical activity throughout the lifecourse on brain health and the risk for dementia and Alzheimer’s disease.

Dr. Spartano also has a major research interest in using mobile health technology to improve health in underserved patient populations at Boston Medical Center. She is exploring the use of continuous glucose monitors as a tool for enhancing lifestyle interventions in patients with and without diabetes mellitus. She shares a MPI role on a Focused Research Project funded by Boston University’s Hariri Institute, which facilitates collaborations of clinical and computational investigators. This team is developing a software platform that can continuously collect mobile health data from research participants and patients. The goal of creating this platform is to address challenges in privacy and in providing timely communication to medically vulnerable patients.

Dr. Spartano also teaches courses for Boston University Graduate Medical Sciences, School of Public Health, and Sargent College of Health Sciences.

Other Positions

  • Investigator, Framingham Heart Study
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Education

  • Tufts University, PhD
  • Tufts University, MS
  • Syracuse University, BS

Classes Taught

  • GMSNU620
  • GMSNU711
  • SARHS742
  • SPHEP758

Publications

  • Published on 6/24/2024

    Grech J, Nkambule BB, Thibord F, Chan M, Lachapelle A, Vasan R, Spartano N, Chen MH, Nayor M, Lewis GD, Johnson AD. Cardiorespiratory Fitness Is Associated with Decreased Platelet Reactivity. Med Sci Sports Exerc. 2024 Jun 24. PMID: 38913957.

    Read at: PubMed
  • Published on 6/13/2024

    Zhang Y, Wang X, Pathiravasan CH, Spartano NL, Lin H, Borrelli B, Benjamin EJ, McManus DD, Larson MG, Vasan RS, Shah RV, Lewis GD, Liu C, Murabito JM, Nayor M. Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study. J Med Internet Res. 2024 Jun 13; 26:e56676. PMID: 38870519.

    Read at: PubMed
  • Published on 6/3/2024

    Alver SK, Pan S, Mossavar-Rahmani Y, Sotres-Alvarez D, Evenson KR, Floyd JS, Xanthakis V, Lin J, Cuthbertson C, Gallo LC, Cai J, Penedo FJ, Llabre MM, Matsushita K, Talavera GA, Pirzada A, Spartano N, Daviglus ML, Vasan RS, Kaplan RC. Physical Activity, Cardiovascular Status, Mortality, and Prediabetes in Hispanic and Non-Hispanic Adults. JAMA Netw Open. 2024 Jun 03; 7(6):e2415094. PMID: 38842811.

    Read at: PubMed
  • Published on 8/24/2023

    Mossavar-Rahmani Y, Lin J, Pan S, Song RJ, Xue X, Spartano NL, Xanthakis V, Sotres-Alvarez D, Marquez DX, Daviglus M, Carlson JA, Parada H, Evenson KR, Talavera AC, Gellman M, Perreira KM, Gallo LC, Vasan RS, Kaplan RC. Characterizing longitudinal change in accelerometry-based moderate-to-vigorous physical activity in the Hispanic Community Health Study/Study of Latinos and the Framingham Heart Study. BMC Public Health. 2023 Aug 24; 23(1):1614. PMID: 37620824.

    Read at: PubMed
  • Published on 7/14/2023

    Wang X, Pathiravasan CH, Zhang Y, Trinquart L, Borrelli B, Spartano NL, Lin H, Nowak C, Kheterpal V, Benjamin EJ, McManus DD, Murabito JM, Liu C. Association of Depressive Symptom Trajectory With Physical Activity Collected by mHealth Devices in the Electronic Framingham Heart Study: Cohort Study. JMIR Ment Health. 2023 Jul 14; 10:e44529. PMID: 37450333.

    Read at: PubMed
  • Published on 6/8/2023

    Perry AS, Dooley EE, Master H, Spartano NL, Brittain EL, Pettee Gabriel K. Physical Activity Over the Lifecourse and Cardiovascular Disease. Circ Res. 2023 Jun 09; 132(12):1725-1740. PMID: 37289900.

    Read at: PubMed
  • Published on 3/6/2023

    Shapira-Daniels A, Kornej J, Spartano NL, Wang X, Zhang Y, Pathiravasan CH, Liu C, Trinquart L, Borrelli B, McManus DD, Murabito JM, Benjamin EJ, Lin H. Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis. J Med Internet Res. 2023 Mar 06; 25:e43123. PMID: 36877540.

    Read at: PubMed
  • Published on 1/20/2023

    Trinquart L, Liu C, McManus DD, Nowak C, Lin H, Spartano NL, Borrelli B, Benjamin EJ, Murabito JM. Increasing Engagement in the Electronic Framingham Heart Study: Factorial Randomized Controlled Trial. J Med Internet Res. 2023 Jan 20; 25:e40784. PMID: 36662544.

    Read at: PubMed
  • Published on 1/1/2023

    Spartano NL, Wang R, Yang Q, Chernofsky A, Murabito JM, Levy D, Vasan RS, DeCarli C, Maillard P, Seshadri S, Beiser AS. Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors. J Alzheimers Dis. 2023; 95(2):561-572. PMID: 37574733.

    Read at: PubMed
  • Published on 12/27/2022

    Pathiravasan CH, Zhang Y, Wang X, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Spartano NL, Schramm E, Liu C, Murabito JM. Factors associated with long-term use of digital devices in the electronic Framingham Heart Study. NPJ Digit Med. 2022 Dec 27; 5(1):195. PMID: 36572707.

    Read at: PubMed

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