Matthew G. Nayor, MD, MPH
Associate Professor, Medicine
Biography
Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women’s Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.
Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.
Other Positions
- Assistant Professor, Preventive Medicine & Epidemiology, Medicine, Boston University Chobanian & Avedisian School of Medicine
Education
- New York University School of Medicine, MD
- Harvard School of Public Health, MPH
- University of Michigan at Ann Arbor, BA
Publications
- Published on 6/28/2024
Miller PE, Gajjar P, Mitchell GF, Khan SS, Vasan RS, Larson MG, Lewis GD, Shah RV, Nayor M. Clusters of multidimensional exercise response patterns and estimated heart failure risk in the Framingham Heart Study. ESC Heart Fail. 2024 Jun 28. PMID: 38943268.
Read at: PubMed - Published on 6/24/2024
Grech J, Nkambule BB, Thibord F, Chan M, Lachapelle A, Vasan R, Spartano N, Chen MH, Nayor M, Lewis GD, Johnson AD. Cardiorespiratory Fitness Is Associated with Decreased Platelet Reactivity. Med Sci Sports Exerc. 2024 Jun 24. PMID: 38913957.
Read at: PubMed - Published on 6/13/2024
Zhang Y, Wang X, Pathiravasan CH, Spartano NL, Lin H, Borrelli B, Benjamin EJ, McManus DD, Larson MG, Vasan RS, Shah RV, Lewis GD, Liu C, Murabito JM, Nayor M. Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study. J Med Internet Res. 2024 Jun 13; 26:e56676. PMID: 38870519.
Read at: PubMed - Published on 6/4/2024
Perry AS, Farber-Eger E, Gonzales T, Tanaka T, Robbins JM, Murthy VL, Stolze LK, Zhao S, Huang S, Colangelo LA, Deng S, Hou L, Lloyd-Jones DM, Walker KA, Ferrucci L, Watts EL, Barber JL, Rao P, Mi MY, Gabriel KP, Hornikel B, Sidney S, Houstis N, Lewis GD, Liu GY, Thyagarajan B, Khan SS, Choi B, Washko G, Kalhan R, Wareham N, Bouchard C, Sarzynski MA, Gerszten RE, Brage S, Wells QS, Nayor M, Shah RV. Proteomic analysis of cardiorespiratory fitness for prediction of mortality and multisystem disease risks. Nat Med. 2024 Jun; 30(6):1711-1721. PMID: 38834850.
Read at: PubMed - Published on 5/14/2024
Kosyakovsky LB, Liu EE, Wang JK, Myers L, Parekh JK, Knauss H, Lewis GD, Malhotra R, Nayor M, Robbins JM, Gerszten RE, Hamburg NM, McNeill JN, Lau ES, Ho JE. Uncovering Unrecognized Heart Failure With Preserved Ejection Fraction Among Individuals With Obesity and Dyspnea. Circ Heart Fail. 2024 May; 17(5):e011366. PMID: 38742409.
Read at: PubMed - Published on 5/3/2024
Ravichandran S, Gajjar P, Walker ME, Prescott B, Tsao CW, Jha M, Rao P, Miller P, Larson MG, Vasan RS, Shah RV, Xanthakis V, Lewis GD, Nayor M. Life's Essential 8 Cardiovascular Health Score and Cardiorespiratory Fitness in the Community. J Am Heart Assoc. 2024 May 07; 13(9):e032944. PMID: 38700001.
Read at: PubMed - Published on 5/3/2024
Murthy VL, Mosley JD, Perry AS, Jacobs DR, Tanriverdi K, Zhao S, Sawicki KT, Carnethon M, Wilkins JT, Nayor M, Das S, Abel ED, Freedman JE, Clish CB, Shah RV. Metabolic liability for weight gain in early adulthood. Cell Rep Med. 2024 May 21; 5(5):101548. PMID: 38703763.
Read at: PubMed - Published on 4/25/2024
Perry AS, Zhang K, Murthy VL, Choi B, Zhao S, Gajjar P, Colangelo LA, Hou L, Rice MB, Carr JJ, Carson AP, Nigra AE, Vasan RS, Gerszten RE, Khan SS, Kalhan R, Nayor M, Shah RV. Proteomics, Human Environmental Exposure, and Cardiometabolic Risk. Circ Res. 2024 Jun 21; 135(1):138-154. PMID: 38662804.
Read at: PubMed - Published on 4/10/2024
Perry AS, Piaggi P, Huang S, Nayor M, Freedman J, North K, Below J, Clish C, Murthy VL, Krakoff J, Shah RV. Human metabolic chambers reveal a coordinated metabolic-physiologic response to nutrition. medRxiv. 2024 Apr 10. PMID: 38645000.
Read at: PubMed - Published on 2/7/2024
Shah RV, Zhong J, Massier L, Tanriverdi K, Hwang SJ, Haessler J, Nayor M, Zhao S, Perry AS, Wilkins JT, Shadyab AH, Manson JE, Martin L, Levy D, Kooperberg C, Freedman JE, Rydén M, Murthy VL. Targeted Proteomics Reveals Functional Targets for Early Diabetes Susceptibility in Young Adults. Circ Genom Precis Med. 2024 Feb; 17(1):e004192. PMID: 38323454.
Read at: PubMed
View 71 more publications: View full profile at BUMC