Matthew G. Nayor, MD, MPH

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women's Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.

Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.

Publications

  • Published 4/23/2026

    Qian F, Gajjar P, Prescott B, Mitchell GF, Xanthakis V, Rade JJ, Nayor M. Modifiable Correlates With Systemic Thromboxane Generation and Association With Cardiovascular Outcomes: Results From the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2026 Jun; 46(6):e324561. PMID: 42021731.

    Read at: PubMed

  • Published 4/7/2026

    Landsteiner I, Stolze LK, Peterson TE, Perry A, Lin P, Sheng Q, Zhao S, Amancherla K, Mi MY, Ikoma T, Cohen LP, Giverts I, Campain J, Lima JAC, Post WS, Taylor KD, Gerszten R, Rich SS, Tracy R, Durda P, Wood AC, Malhotra R, Rotter JI, Clish C, Nayor M, Gamazon ER, Shah RV, Lewis GD. Multi-Organ Physiologic Deficits During Exercise Identify Clinical and Molecular Predisposition to Heart Failure with Preserved Ejection Fraction. Circulation. 2026 Apr 07; 153(18):1362-84. PMID: 41944041.

    Read at: PubMed

  • Published 4/2/2026

    El-Sabawi B, Huang X, Lin P, Anwar MY, Betti M, Kim N, Perry AS, Perera BLA, Gajjar P, Colangelo LA, Amancherla K, Sheng Q, Zhao S, Stolze LK, Farber-Eger E, Landman JM, Miller PE, Liu GY, Das S, Wells QS, Terry JG, Lloyd-Jones D, Das S, Khan SS, North KE, Below J, Nayor M, Kalhan R, Carr JJ, Gamazon ER, Shah RV. Proteogenomic Analysis of Coronary Artery Calcification in Human Populations. Arterioscler Thromb Vasc Biol. 2026 Jun; 46(6):e324171. PMID: 41924874.

    Read at: PubMed

  • Published 3/2/2026

    Qian F, Davis DN, Nayor M. Healthy Lifestyle After Hypertension-A Call to Action. JAMA Netw Open. 2026 Mar 02; 9(3):e260927. PMID: 41842902.

    Read at: PubMed

  • Published 2/17/2026

    Perry AS, O'Connor C, Pavicic M, Sheng Q, Farber-Eger E, Sarkar A, Lin P, Evans P, Tanriverdi K, Risitano A, Peters AE, Chen H, Upadhya B, Whellan DJ, Pastva A, Mentz RJ, Bertoni A, Semelka C, Brubaker PH, Molina AJA, Newland R, Nelson B, Lane M, Sullivan KA, Townsend A, Vlot A, Nsoh B, Allen PD, Wells Q, Reeves GR, Jacobson D, Kitzman DW, Gamazon ER, Nayor M, Shah RV. A multi-layered approach to elucidate mechanisms of physical function in response to rehabilitation in heart failure with preserved ejection fraction. medRxiv. 2026 Feb 17. PMID: 41757200.

    Read at: PubMed

Other Positions

  • Assistant Professor, Medicine
    Boston University Chobanian & Avedisian School of Medicine

Education

  • New York University School of Medicine, MD
  • Harvard School of Public Health, MPH
  • University of Michigan at Ann Arbor, BA