Mary Fisher, MD, PhD

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Fisher’s work has been instrumental in establishing the zebrafish as a model organism for the study of skeletal dysplasias, including her identical for a zebrafish model for Osteogenesis Imperfection and publication of the first osteoblast markers. She pioneered the use of zebrafish to analyze transcriptional and regulatory elements from the human genome, and has identified and studied dozens of enhancers associated with skeletal genes. Her most recent efforts are focused on skull development, an area of tremendous clinical relevance not well studied in zebrafish.

Publications

  • Published 6/10/2016

    Brinkley JF, Fisher S, Harris MP, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Maas RL, Marazita ML, Selleri L, Spritz RA, van Bakel H, Visel A, Williams TJ, Wysocka J, Chai Y. The FaceBase Consortium: a comprehensive resource for craniofacial researchers. Development. 2016 Jul 15; 143(14):2677-88. PMID: 27287806.

    Read at: PubMed

  • Published 3/16/2016

    Kague E, Roy P, Asselin G, Hu G, Simonet J, Stanley A, Albertson C, Fisher S. Osterix/Sp7 limits cranial bone initiation sites and is required for formation of sutures. Dev Biol. 2016 May 15; 413(2):160-72. PMID: 26992365.

    Read at: PubMed

  • Published 9/11/2014

    Esteves FF, Springhorn A, Kague E, Taylor E, Pyrowolakis G, Fisher S, Bier E. BMPs regulate msx gene expression in the dorsal neuroectoderm of Drosophila and vertebrates by distinct mechanisms. PLoS Genet. 2014 Sep; 10(9):e1004625. PMID: 25210771.

    Read at: PubMed

  • Published 7/1/2013

    Costa AM, Pereira-Castro I, Ricardo E, Spencer F, Fisher S, da Costa LT. GRG5/AES interacts with T-cell factor 4 (TCF4) and downregulates Wnt signaling in human cells and zebrafish embryos. PLoS One. 2013; 8(7):e67694. PMID: 23840876.

    Read at: PubMed

  • Published 11/14/2012

    Kague E, Gallagher M, Burke S, Parsons M, Franz-Odendaal T, Fisher S. Skeletogenic fate of zebrafish cranial and trunk neural crest. PLoS One. 2012; 7(11):e47394. PMID: 23155370.

    Read at: PubMed

View All 30 Publications:   View Full Profile in BUMC

Other Positions

  • Member, Genome Science Institute
    Boston University
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Websites

Education

  • Johns Hopkins University School of Medicine, MD
  • Johns Hopkins University School of Medicine, PhD
  • Purdue University, BS

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