Marie-Helene Saint-Hilaire, MD
Professor, Neurology
Biography
Dr. Saint-Hilaire received her MD from the Université de Montréal, Canada in 1980 and completed her Neurology residency at the Montréal Neurological Institute (MNI). She then completed a year of fellowship in epilepsy at the MNI, followed by a 3-year movement disorders fellowship working in varied institutions consisting of one year in Paris with Pr. Yves Agid, one year in New York at Columbia Presbyterian Hospital with Dr. Stanley Fahn, and one year at Boston University with Dr. Robert Feldman. In 1988, she joined Boston University Department of Neurology.
Dr. Saint-Hilaire is board-certified in Neurology and is fellowship trained in Movement Disorders. She is dedicated to the delivery of highly specialized and compassionate care. This care is aimed at improving the quality of life of Parkinson’s disease patients and their families. Her clinical practice includes the diagnosis and management of all of the neurological movement disorders.
Additionally, she is the Director of the American Parkinson Disease Association Center for Advanced Research at Boston University. She has participated in more than 100 research trials and has written more than 100 articles and book chapters. Her research interests include studying new therapies that may modify disease progression and/or treat symptoms and complications of therapy. Additionally, she is interested in research investigating environmental and genetic causes of PD. She frequently collaborates with other disciplines to design and implement clinical trials. She is a member of the Parkinson Study Group (PSG), the Huntington Study Group (HSG), and the Movement Disorder Society. She currently is a member of the PSG Scientific Review Committee. She has served on the Scientific Advisory Board for the American Parkinson Disease Association since 2007.
Dr. Saint-Hilaire directs the movement disorders fellowship at BUSM. She is actively involved in the training of residents and medical students at BUSM. She has received the Teaching Award on three occasions, and the Mentorship Award on one occasion, both presented by Neurology Residents.
As the Medical Director of the American Parkinson Disease Association Information and Referral Center, she is dedicated to the New England Parkinson community and has provided over 200 presentations to health professional and lay groups. She is an advisor to the APDA Massachusetts Chapter. In 2016, she received the Shawn Thornton Award for Excellence in Support of the Parkinson’s Community.
Other Positions
- Ad Interim Chair, Neurology, Boston University Chobanian & Avedisian School of Medicine
Education
- Université de Montréal, MD
- Collège Marie de France, BA
Publications
- Published on 7/4/2024
Xue C, Kowshik SS, Lteif D, Puducheri S, Jasodanand VH, Zhou OT, Walia AS, Guney OB, Zhang JD, Pham ST, Kaliaev A, Andreu-Arasa VC, Dwyer BC, Farris CW, Hao H, Kedar S, Mian AZ, Murman DL, O'Shea SA, Paul AB, Rohatgi S, Saint-Hilaire MH, Sartor EA, Setty BN, Small JE, Swaminathan A, Taraschenko O, Yuan J, Zhou Y, Zhu S, Karjadi C, Alvin Ang TF, Bargal SA, Plummer BA, Poston KL, Ahangaran M, Au R, Kolachalama VB. AI-based differential diagnosis of dementia etiologies on multimodal data. Nat Med. 2024 Oct; 30(10):2977-2989. PMID: 38965435.
Read at: PubMed - Published on 3/26/2024
Xue C, Kowshik SS, Lteif D, Puducheri S, Jasodanand VH, Zhou OT, Walia AS, Guney OB, Zhang JD, Pham ST, Kaliaev A, Andreu-Arasa VC, Dwyer BC, Farris CW, Hao H, Kedar S, Mian AZ, Murman DL, O'Shea SA, Paul AB, Rohatgi S, Saint-Hilaire MH, Sartor EA, Setty BN, Small JE, Swaminathan A, Taraschenko O, Yuan J, Zhou Y, Zhu S, Karjadi C, Ang TFA, Bargal SA, Plummer BA, Poston KL, Ahangaran M, Au R, Kolachalama VB. AI-based differential diagnosis of dementia etiologies on multimodal data. medRxiv. 2024 Mar 26. PMID: 38585870.
Read at: PubMed - Published on 4/4/2023
Girnis JL, Cavanaugh JT, Baker TC, Duncan RP, Fulford D, LaValley MP, Lawrence M, Nordahl T, Porciuncula F, Rawson KS, Saint-Hilaire M, Thomas CA, Zajac JA, Earhart GM, Ellis TD. Natural Walking Intensity in Persons With Parkinson Disease. J Neurol Phys Ther. 2023 Jul 01; 47(3):146-154. PMID: 37016469.
Read at: PubMed - Published on 2/28/2023
Saint-Hilaire MH, Thomas CA. Delivering a Diagnosis of Parkinson's Disease and Parkinsonism with Wisdom and Sensitivity. Semin Neurol. 2023 Feb; 43(1):178-184. PMID: 36854395.
Read at: PubMed - Published on 11/15/2022
Zajac JA, Cavanaugh JT, Baker T, Duncan RP, Fulford D, Girnis J, LaValley M, Nordahl T, Porciuncula F, Rawson KS, Saint-Hilaire M, Thomas CA, Earhart GM, Ellis TD. Does clinically measured walking capacity contribute to real-world walking performance in Parkinson's disease? Parkinsonism Relat Disord. 2022 Dec; 105:123-127. PMID: 36423521.
Read at: PubMed - Published on 6/20/2022
Qiu S, Miller MI, Joshi PS, Lee JC, Xue C, Ni Y, Wang Y, De Anda-Duran I, Hwang PH, Cramer JA, Dwyer BC, Hao H, Kaku MC, Kedar S, Lee PH, Mian AZ, Murman DL, O'Shea S, Paul AB, Saint-Hilaire MH, Alton Sartor E, Saxena AR, Shih LC, Small JE, Smith MJ, Swaminathan A, Takahashi CE, Taraschenko O, You H, Yuan J, Zhou Y, Zhu S, Alosco ML, Mez J, Stein TD, Poston KL, Au R, Kolachalama VB. Multimodal deep learning for Alzheimer's disease dementia assessment. Nat Commun. 2022 Jun 20; 13(1):3404. PMID: 35725739.
Read at: PubMed - Published on 10/1/2021
Zajac JA, Cavanaugh JT, Baker T, Colón-Semenza C, DeAngelis TR, Duncan RP, Fulford D, LaValley M, Nordahl T, Rawson KS, Saint-Hilaire M, Thomas CA, Earhart GM, Ellis TD. Are Mobile Persons With Parkinson Disease Necessarily More Active? J Neurol Phys Ther. 2021 10 01; 45(4):259-265. PMID: 34091569.
Read at: PubMed - Published on 9/14/2021
Schwarzschild MA, Ascherio A, Casaceli C, Curhan GC, Fitzgerald R, Kamp C, Lungu C, Macklin EA, Marek K, Mozaffarian D, Oakes D, Rudolph A, Shoulson I, Videnovic A, Scott B, Gauger L, Aldred J, Bixby M, Ciccarello J, Gunzler SA, Henchcliffe C, Brodsky M, Keith K, Hauser RA, Goetz C, LeDoux MS, Hinson V, Kumar R, Espay AJ, Jimenez-Shahed J, Hunter C, Christine C, Daley A, Leehey M, de Marcaida JA, Friedman JH, Hung A, Bwala G, Litvan I, Simon DK, Simuni T, Poon C, Schiess MC, Chou K, Park A, Bhatti D, Peterson C, Criswell SR, Rosenthal L, Durphy J, Shill HA, Mehta SH, Ahmed A, Deik AF, Fang JY, Stover N, Zhang L, Dewey RB, Gerald A, Boyd JT, Houston E, Suski V, Mosovsky S, Cloud L, Shah BB, Saint-Hilaire M, James R, Zauber SE, Reich S, Shprecher D, Pahwa R, Langhammer A, LaFaver K, LeWitt PA, Kaminski P, Goudreau J, Russell D, Houghton DJ, Laroche A, Thomas K, McGraw M, Mari Z, Serrano C, Blindauer K, Rabin M, Kurlan R, Morgan JC, Soileau M, Ainslie M, Bodis-Wollner I, Schneider RB, Waters C, Ratel AS, Beck CA, Bolger P, Callahan KF, Crotty GF, Klements D, Kostrzebski M, McMahon GM, Pothier L, Waikar SS, Lang A, Mestre T. Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial. JAMA. 2021 09 14; 326(10):926-939. PMID: 34519802.
Read at: PubMed - Published on 4/15/2021
Irwin D, Saint-Hilaire M. In Vivo Detection of Underlying Synucleinopathies: Are We There Yet? Neurology. 2021 05 18; 96(20):925-926. PMID: 33858996.
Read at: PubMed - Published on 9/20/2020
Mills KA, Schneider RB, Saint-Hilaire M, Ross GW, Hauser RA, Lang AE, Halverson MJ, Oakes D, Eberly S, Litvan I, Blindauer K, Aquino C, Simuni T, Marras C. Cognitive impairment in Parkinson's disease: Associations between subjective and objective cognitive decline in a large longitudinal study. Parkinsonism Relat Disord. 2020 11; 80:127-132. PMID: 32987359.
Read at: PubMed
View 71 more publications: View full profile at BUMC